The Relationship between Resilience and Mental Health: the Mediating Effect of Positive Emotions

To investigate the relationship of resilience, positive emotions and mental health, and the relationship of resilience, positive emotion and three sub-dimensions of mental health: self-affirmation, depression and anxiety. In this study, the existing cross-sectional data, select the Beijing Forestry University data as samples. In this study, questionnaire survey a random sample of 199 undergraduate students of Beijing Forestry University, they uniform application three Scale Surveying, PANAS, CD-RISC, GHQ-20. According from the study, (1) resilience, positive mood and general health are related where resilience and positive emotions between the resilience. General psychological health, positive emotions and general mental health?it is positively correlated. (2) Resilience and self-affirmation exists, positive correlation with depression and anxiety, respectively negative correlation. Between positive emotions and self-affirmation the positive correlation with anxiety negative correlation. (3) Part mediating effect of positive emotions exist between resilience and self-affirmation, resilience can be made to self-affirmation prediction coefficient from 0.042 down to 0.036. Therefore, this study concluded that resilience undergraduates can have an impact on mental health through the intermediary variable positive emotions

Research on the Relationship between Positive Emotions, Psychological Capital and Job Burnout in Enterprises’ Employees: Based on the Broaden-and-Build Theory of Positive Emotions

At present, the research on the positive emotions of employees in management scholars is a little inadequate. This study uses a questionnaire survey to measure 385 employees from Chinese Enterprises, focusing on the relationship between positive emotions and job burnout, and emphatically examines the mediating effect of psychological capital. The results show that positive emotions of employees are positively correlated with psychological capital and negatively correlated with job burnout. Psychological capital plays a complete mediator between positive emotions and job burnout. This study has some guiding significance for the construction of healthy society and organization

Cross-Modality Perturbation Synergy Attack for Person Re-identification

In recent years, there has been significant research focusing on addressing security concerns in single-modal person re-identification (ReID) systems that are based on RGB images. However, the safety of cross-modality scenarios, which are more commonly encountered in practical applications involving images captured by infrared cameras, has not received adequate attention. The main challenge in cross-modality ReID lies in effectively dealing with visual differences between different modalities. For instance, infrared images are typically grayscale, unlike visible images that contain color information. Existing attack methods have primarily focused on the characteristics of the visible image modality, overlooking the features of other modalities and the variations in data distribution among different modalities. This oversight can potentially undermine the effectiveness of these methods in image retrieval across diverse modalities. This study represents the first exploration into the security of cross-modality ReID models and proposes a universal perturbation attack specifically designed for cross-modality ReID. This attack optimizes perturbations by leveraging gradients from diverse modality data, thereby disrupting the discriminator and reinforcing the differences between modalities. We conducted experiments on two widely used cross-modality datasets, namely RegDB and SYSU, which not only demonstrated the effectiveness of our method but also provided insights for future enhancements in the robustness of cross-modality ReID systems

Hydrogen Sulfide Attenuated Tumor Necrosis Factor-α-Induced Inflammatory Signaling and Dysfunction in Vascular Endothelial Cells

S donor) on tumor necrosis factor (TNF)-α-induced human umbilical vein endothelial cells (HUVEC) dysfunction.Application of NaHS concentration-dependently suppressed TNF-α-induced mRNA and proteins expressions of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), mRNA expression of P-selectin and E-selectin as well as U937 monocytes adhesion to HUVEC. Western blot analysis revealed that the expression of the cytoprotective enzyme, heme oxygenase-1 (HO-1), was induced and coincident with the anti-inflammatory action of NaHS. Furthermore, TNF-α-induced NF-κB activation assessed by IκBα degradation and p65 phosphorylation and nuclear translocation and ROS production were diminished in cells subjected to treatment with NaHS.S can exert an anti-inflammatory effect in endothelial cells through a mechanism that involves the up-regulation of HO-1

Post-capitalist property

When writing about property and property rights in his imagined post-capitalist society of the future, Marx seemed to envisage ‘individual property’ co-existing with ‘socialized property’ in the means of production. As the social and political consequences of faltering growth and increasing inequality, debt and insecurity gradually manifest themselves, and with automation and artificial intelligence lurking in the wings, the future of capitalism, at least in its current form, looks increasingly uncertain. With this, the question of what property and property rights might look like in the future, in a potentially post-capitalist society, is becoming ever more pertinent. Is the choice simply between private property and markets, and public (state-owned) property and planning? Or can individual and social property in the (same) means of production co-exist, as Marx suggested? This paper explores ways in which they might, through an examination of the Chinese household responsibility system (HRS) and the ‘fuzzy’ and seemingly confusing regime of land ownership that it instituted. It examines the HRS against the backdrop of Marx’s ideas about property and subsequent (post-Marx) theorizing about the legal nature of property in which property has come widely to be conceptualized not as a single, unitary ‘ownership’ right to a thing (or, indeed, as the thing itself) but as a ‘bundle of rights’. The bundle-of-rights idea of property, it suggests, enables us to see not only that ‘individual’ and ‘socialized’ property’ in the (same) means of production might indeed co-exist, but that the range of institutional possibility is far greater than that between capitalism and socialism/communism as traditionally conceived

Effects of Personality on Risky Driving Behavior and Accident Involvement for Chinese Drivers

Objective: Motor vehicle accidents are the leading cause of injury-related fatalities in China and pose the most serious threat to driving safety. Driver personality is considered as an effective predictor for risky driving behavior and accident liability. Previous studies have focused on the relationship between personality and risky driving behavior, but only a few of them have explored the effects of personality variables on accident involvement. In addition, few studies have examined the effects of personality on Chinese drivers' risky driving and accident involvement. The present study aimed to examine the effects of personality variables on Chinese drivers' unsafe driving behaviors and accident involvement. Methods: Two hundred and twenty-four Chinese drivers aged 20 to 50 were required to complete questionnaires assessing their personality traits (anger, sensation-seeking, altruism, and normlessness), risky driving behaviors (aggressive violations, ordinary violations), and accident involvement (all accidents, serious accidents, at-fault accidents). Multivariate regression analyses, adjusting for gender, age, and overall mileage, were conducted to identify the personality traits related to risky driving behaviors and accident involvement. Results: Participants' personality traits were found to be significantly correlated with both risky driving behavior and accident involvement. Specifically, the traits of anger and normlessness were effective predictors for aggressive violations. The traits of anger, sensation-seeking, normlessness, and altruism were effective predictors for ordinary violations. Moreover, altruism and normlessness were significant predictors for the total number of accidents participants had during the past 3years. Conclusions: Consistent with previous studies, the present study revealed that personality traits play an important role in predicting Chinese drivers' risky driving behaviors. In addition, Chinese drivers' personality characteristics were also associated with accident involvement. Supplemental materials are available for this article. Go to the publisher's online edition of Traffic Injury Prevention to view the supplemental file

Cooperative co-evolutionary algorithm for multi-objective optimization problems with changing decision variables

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Multi-objective optimization problems (MOPs) with changing decision variables exist in the actual industrial production and daily life, which have changing Pareto sets and complex relations among decision variables and are difficult to solve. In this study, we present a cooperative co-evolutionary algorithm by dynamically grouping decision variables to effectively tackle MOPs with changing decision variables. In the presented algorithm, decision variables are grouped into a series of groups using maximum entropic epistasis (MEE) at first, with decision variables in different groups owning a weak dependency. Subsequently, a sub-population is generated to solve decision variables in each group with an existing multi-objective evolutionary algorithm (MOEA). Further, a complete solution including all the decision variables is achieved through the cooperation among sub-populations. Finally, when a decision variable is added or deleted from the existing problem, the grouping of decision variables is dynamically adjusted based on the correlation between the changed decision variable and existing groups. To verify the performance of the developed method, the presented method is compared with five popular methods by tackling eight benchmark optimization problems. The experimental results reveal that the presented method is superior in terms of diversity, convergence, and spread of solutions on most benchmark optimization problems

ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway

Abstract Background Osteosarcoma is a diverse and aggressive bone tumor. Driver genes regulating osteosarcoma initiation and progression remains incompletely defined. Zinc finger protein 692 (ZNF692), a kind of Krüppel C2H2 zinc finger transcription factor, exhibited abnormal expression in different types of malignancies and showed a correlation with the clinical prognosis of patients as well as the aggressive characteristics of cancer cells. Nevertheless, its specific role in osteosarcoma is still not well understood. Methods We investigated the dysregulation and clinical significance of ZNF692 in osteosarcoma through bioinformatic method and experimental validation. A range of in vitro assays, including CCK-8, colony formation, EdU incorporation, wound healing, and transwell invasion tests, were conducted to assess the impact of ZNF692 on cell proliferation, migration, and invasion in osteosarcoma. A xenograft mouse model was established to evaluate the effect of ZNF692 on tumor growth in vivo. Western blot assay was used to measure the protein levels of MEK1/2, P-MEK1/2, ERK1/2, and P-ERK1/2 in cells that had been genetically modified to either reduce or increase the expression of ZNF692. The relationship between ZNF692 and tyrosine kinase non-receptor 2 (TNK2) were validated by qRT-PCR, chromatin immunoprecipitation and luciferase reporter assays. Results Expression of ZNF692 was increased in both human osteosarcoma tissues and cell lines. Furthermore, the expression of ZNF692 served as an independent predictive biomarker in osteosarcoma. The results of the survival analysis indicated that increased expression of ZNF692 was associated with worse outcome. Downregulation of ZNF692 inhibits the proliferation, migration, and invasion of osteosarcoma cells, whereas upregulation of ZNF692 has the opposite impact. Western blot assay indicates that reducing ZNF692 decreases phosphorylation of MEK1/2 and ERK1/2, whereas increasing ZNF692 expression enhances their phosphorylation. U0126, a potent inhibitor specifically targeting the MEK/ERK signaling pathway, partially counteracts the impact of ZNF692 overexpression on the proliferation, migration, and invasion of osteosarcoma cells. In addition, ZNF692 specifically interacts with the promoter region of TNK2 and stimulates the transcription of TNK2 in osteosarcoma cells. Forcing the expression of TNK2 weakens the inhibitory impact of ZNF692 knockdown on P-MEK1/2 and P-ERK1/2. Similarly, partly inhibiting TNK2 counteracts the enhancing impact of ZNF692 overexpression on the phosphorylation of MEK1/2 and ERK1/2. Functional tests demonstrate that the suppressive effects of ZNF692 knockdown on cell proliferation, migration, and invasion are greatly reduced when TNK2 is overexpressed. In contrast, the reduction of TNK2 hinders the ability of ZNF692 overexpression to enhance cell proliferation, migration, and invasion. Conclusion ZNF692 promotes the proliferation, migration, and invasion of osteosarcoma cells via the TNK2-dependent stimulation of the MEK/ERK signaling pathway. The ZNF692-TNK2 axis might potentially function as a possible predictive biomarker and a promising target for novel therapeutics in osteosarcoma

Additional file 1 of ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway

Supplementary Material