1 research outputs found
Experimental Model of Pancreonecrosis Induced by Auto-bile Injection
AIM: The aim of the study is to create an easily reproducible experimental model of pancreonecrosis with the least aggressive technique of the operation.
METHODS: Twenty-two outbred rabbits of comparable weight and age were included in the study. The animals were removed from the experiment 12, 24, and 48 h after the injection of auto-bile into the parenchyma of the pancreas.
RESULTS: After completion of the experiment, rabbit pancreas was extracted, macroscopic and microscopic description was given.
CONCLUSION: According to the results of the study, the proposed model is considered as consistent for reproducing pancreonecrosis in an experiment with less aggressive surgical technique