1,207 research outputs found

    VALUE CREATION THROUGH INTER-ORGANIZATIONAL SYSTEMS (IOS): FROM GOVERNANCE PROCESS VIEW

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    In this study, we seek to reveal the mechanism of value creation between firms and their partners in B2B context. An integrated conceptual model is constructed grounded in the co-creation theory and the process view, which proposes the interaction between relational assets, IOS support and governance process, as well as their impacts on co-created value. It differs from previous studies by highlighting the mediating effect of governance on value creation. Using a sample of 181 collected from China, our analysis indicates the contribution of governance to co-created value, which is generated through IOS and relational assets. In fact, the IOS support and relational assets alone don’t hold the answer to value co-creation, but they affect the mediating process and enable governance to create value. Especially, the IOS could accommodate the use of relational assets and significantly affect governance process, which is found to be fundamental in value creation. While commodity-like resources have diminishing value in co-creation, governance process with causal ambiguity, social complexity and organizational interconnectedness, becomes the main source of co-created value. Overall, our research sheds light on the key drivers of value co-creation, and provides insights to their impacts on value creation

    Bis(1,10-phenanthroline-κ2 N,N′)(sulfato-κ2 O,O′)nickel(II) ethane-1,2-diol solvate

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    In the title compound, [Ni(SO4)(C12H8N2)2]·C2H6O2, the coordination polyhedron around the Ni2+ ion is a distorted octahedron, with four N atoms from two phenanthroline groups and two O atoms from a bidentate sulfate ligand. The Ni2+ ion lies on a special position of site symmetry 2. Inter­molecular O—H⋯O hydrogen bonds help to stabilize the structure. The OH group of the ethane-1,2-diol solvent is disordered over two positions with equal occupancy

    Assessment of cardiac dysfunction by dissipative energy loss derived from vector flow mapping

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    Prevalence survey on pterygium among people aged 40 and above in Hengli Town of Dongguan

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    AIM:To investigate the prevalence of pterygium of the household population aged 40 and above in Hengli Town of Dongguan.<p>METHODS: Using the method of cluster random sampling, select 3 628 people aged 40 and above in four villages and one community for visual examination, intraocular pressure check, slit lamp examination and questionnaire.<p>RESULTS: The actual number of subjects was 3 393 people, and examination rate was 93.52%. We detected 843 patients with pterygium. The prevalence of pterygium was 24.85%.<p>CONCLUSION: There is high prevalence of pterygium in Dongguan area. The prevalence of pterygium is related with age and working environment, but has no relation with gender

    The chaperone activity of trigger factor is distinct from its isomerase activity during co-expression with adenylate kinase in Escherichia coli

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    AbstractTo investigate the molecular chaperone function of trigger factor (TF) and its relationship with isomerase activity in vivo, the assisted folding of adenylate kinase (AK) by TF in Escherichia coli was examined by measuring the amounts of soluble AK produced during co-expression. When the mutant of chicken AK, P17G, is expressed in plasmid pBVAK, 95% of the protein is found in inclusion bodies. Co-expression of AK with TF was achieved using a plasmid pBVAT that allowed expression of TF and AK in the same plasmid under separate control. Co-expression with TF resulted in an increase in the amount of soluble AK, with a higher increase when TF was expressed at higher levels in the cell. Co-expression of AK with the two TF mutants, Y221G and F233Y, in which peptidyl-prolyl cis/trans isomerase activity was 1% of wild-type, gave the same results as wild-type TF. This provides in vivo evidence that the molecular chaperone activity of TF is distinct from its isomerase activity

    1,4-Dibromo-2,5-dimeth­oxy­benzene

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    The asymmetric unit of the title compound, C8H8Br2O2, contains one half-mol­ecule, the complete mol­ecule being generated by inversion symmetry

    The cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments

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    <p>Abstract</p> <p>Background</p> <p>EV71 occasionally cause a series of severe neurological symptoms, including aseptic meningitis, encephalitis, and poliomyelitis-like paralysis. However, the neurological destruction mechanism was remained to be clarified. This study described the cross reaction between EV71 induced IgG and human brain tissue.</p> <p>Results</p> <p>Cross reaction of the IgG from 30 EV71 infected patients' sera to human tissues of cerebra was observed, which suggested that some EV71 antigens could induce IgG cross-reactivity to human cerebra. To identify the regions of EV71 virus that containing above antigens, the polypeptide of virus was divided into 19 peptides by expression in prokaryotes cell. Mouse anti-sera of these peptides was prepared and applied in immunohistochemical staining with human adult and fetus brain tissue, respectively. The result indicated the 19 peptides can be classified into three groups: strong cross-reactivity, weak cross-reactivity and no cross-reactivity with human brain tissue according the cross reaction activity. Then, the increased Blood Brain Barrier (BBB) permeability and permits IgG entry in neonatal mice after EV71 infection was determined.</p> <p>Conclusion</p> <p>EV71 induced IgG could enter BBB and cross-reacted with brain tissue in EV71 infected neonatal mice, and then the peptides of EV71 that could induce cross-reactivity with brain tissue were identified, which should be avoided in future vaccine designing.</p

    Research progress on degradative solvent extraction of low-rank coals

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    The degradative solvent extraction of low rank coal is the use of solvents to extract low rank coal under mild conditions, through the dehydration and multi-stage separation of the raw coal: the extraction products with no water content, no ash content, high calorific value properties and excellent thermoplastic properties, and low moisture of the extractive residual coal can be obtained. At the same time, the products have practical application advantages in many fields such as coal coking, advanced fuel and carbon material preparation, which have high added value, and the solvent in this technology has the advantage of being recyclable. Therefore, degradative solvent extraction is one of the effective ways to realize the graded fractionated conversion and utilization of low-rank coal. This review firstly introduces the existing low rank coal upgrading methods, and then reviews the development of degradative solvent extraction, focusing on the various influencing factors, reaction mechanisms, existing processes and product utilization of low rank coal upgrading by degradative solvent extraction. Finally, using the "Web of Science core collection" as the data source, the knowledge graph of coal solvent extraction was carved using CiteSpace scientometric software, and the research themes were analyzed to summarize the research directions and predict the research hotspots, providing some reference value for the research of degradative solution extraction of low-rank coal. The comprehensive analysis shows that: the selection of new low-cost green solvents, structural characterization and high-value utilization of extraction products have high research trends, while in-depth research on extraction mechanism and targeted regulation of extractant properties is needed to further promote the process of large-scale production
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