CoCoFormer: A controllable feature-rich polyphonic music generation method

This paper explores the modeling method of polyphonic music sequence. Due to the great potential of Transformer models in music generation, controllable music generation is receiving more attention. In the task of polyphonic music, current controllable generation research focuses on controlling the generation of chords, but lacks precise adjustment for the controllable generation of choral music textures. This paper proposed Condition Choir Transformer (CoCoFormer) which controls the output of the model by controlling the chord and rhythm inputs at a fine-grained level. In this paper, the self-supervised method improves the loss function and performs joint training through conditional control input and unconditional input training. In order to alleviate the lack of diversity on generated samples caused by the teacher forcing training, this paper added an adversarial training method. CoCoFormer enhances model performance with explicit and implicit inputs to chords and rhythms. In this paper, the experiments proves that CoCoFormer has reached the current better level than current models. On the premise of specifying the polyphonic music texture, the same melody can also be generated in a variety of ways

3,5-Di-O-benzoyl-1,2-O-isopropyl­idene-α-d-ribo-hexos-3-ulo-1,4:3,6-difuran­ose

The title compound, C23H22O8, is a binary benzoyl ester whose nucleus consists of a fused system made up of a methyl­enedi­oxy ring and two tetra­hydro­furan rings. One of the benzoyl ester groups is attached at the junction of the two tetra­hydro­furan rings. The other is attached to the outer tetra­furan ring. Both the benzoyl ester groups are in an axial conformation with respect to the outer tetrhydro­furan ring. In the crystal, mol­ecules are linked by two weak C—H⋯O hydrogen bonds, forming a chain running parallel to the a axis

The correlation between the expression of differentiated embryo-chondrocyte expressed gene l and oral squamous cell carcinoma

BACKGROUND: This study aims to explore the correlation between expression of differentiated embryo-chondrocyte expressed gene l (DEC1) and oral squamous cell carcinoma (OSCC), which could provide the reference for treatment and prognosis assessment of OSCC. METHODS: The expression of DEC1 in tissues from 56 primary OSCC patients and 20 normal oral mucosa samples were detected using real-time polymerase chain reaction and immunohistochemical methods, respectively. RESULTS: The results showed that the positive expression rate of DEC1 in the OSCC group was significantly higher than that in the normal group (P <0.05); further, the expression of DEC1 in different OSCC groups was statistically significant (P <0.05). The expression of DEC1 in the 1-year recurrence OSCC group was significantly higher than other groups. The expression of DEC1 in the 3-years no recurrence OSCC group was the lowest. CONCLUSIONS: The expression of DEC1 was associated with the incidence of OSCC and there was a negative correlation between the expression of DEC1 and the prognosis of OSCC

Developmental potential of non- and mono-pronuclear zygotes and associated clinical outcomes in IVF cycles

PurposeThis study aims to evaluate the developmental potential of 0PN, 1PN, and 2PN zygotes in IVF cycles and compare their clinical outcomes.MethodsWe conducted a retrospective cohort study involving IVF patients. Blastocyst formation rates were assessed with 0PN, 1PN, and 2PN zygotes. Subsequently, we collected clinical outcome data following the transfer of these zygotes.ResultsThe overall blastulation rate was similar between 0PN (29.6%) and 2PN (32.1%) zygotes, but 1PN zygotes exhibited a significantly lower blastulation rate (17.0%) compared to both 0PN and 2PN zygotes. Similarly, the overall rate of good-quality blastulation was comparable between 0PN (15.3%) and 2PN (17.5%) zygotes, while 1PN zygotes showed a significantly lower rate (7.0%) compared to both 0PN and 2PN. Clinical pregnancy, ectopic pregnancy, implantation, and live birth rates were similar among single blastocyst frozen embryo transfers (FET) of 0PN, 1PN, and 2PN. Additionally, no significant differences were observed between single- and double-blastocyst FET of 0PN and 2PN.ConclusionsOur findings suggest that 0PN and 2PN zygotes have comparable developmental potential, while 1PN embryos exhibit lower developmental potential. Blastocyst FET outcomes appear similar among 0PN, 1PN, and 2PN zygotes