197 research outputs found
Intrinsic spin Hall effect in monolayers of group-VI dichalcogenides: A first-principles study
Using first-principles calculations within density functional theory, we
investigate the intrinsic spin Hall effect in monolayers of group-VI
transition-metal dichalcogenides MX2 (M = Mo, W and X = S, Se). MX2 monolayers
are direct band-gap semiconductors with two degenerate valleys located at the
corners of the hexagonal Brillouin zone. Because of the inversion symmetry
breaking and the strong spin-orbit coupling, charge carriers in opposite
valleys carry opposite Berry curvature and spin moment, giving rise to both a
valley- and a spin-Hall effect. The intrinsic spin Hall conductivity (ISHC) in
p-doped samples is found to be much larger than the ISHC in n-doped samples due
to the large spin-splitting at the valence band maximum. We also show that the
ISHC in inversion-symmetric bulk dichalcogenides is an order of magnitude
smaller compared to monolayers. Our result demonstrates monolayer
dichalcogenides as an ideal platform for the integration of valleytronics and
spintronics.Comment: published version (7 pages, 6 figures
The Role of SPARC Protein Expression in the Progress of Gastric Cancer
We aimed to investigate the expression of SPARC (secreted protein, acidic and rich in cysteine) in gastric cancer and its relationship with tumor angiogenesis and cancer cells proliferation. Protein expression of SPARC, VEGF, CD34 and Ki-67 in 80 cases of gastric cancer and 30 cases of normal gastric tissue was evaluated by immunohistochemistry. CD34 staining was used as an indicator of microvessel density (MVD). Ki-67 labeling Index (LI) indicated cancer cells proliferation. Statistical analysis was used to investigate its relationship with clinical characteristics, tumor angiogenesis and cancer cells proliferation. SPARC expression was mainly in the stromal cells surrounding the gastric cancer cells, and was statistically significant differences between gastric cancer and normal gastric tissue (P < 0.05). Both the expression of SPARC and VEGF were related to differentiation degree, clinical stage, Lauren classification and lymph node metastasis (P < 0.05). Expression of SPARC was significantly negatively correlated with the expression of VEGF and MVD in gastric cancer tissues. Expression of SPARC was also negatively correlated with Ki-67-LI. Our findings suggest that both the expression of SPARC and VEGF are closed to tumor angiogenesis in gastric cancer, SPARC inhibited tumor angiogenesis but VEGF promoted tumor angiogenesis. SPARC also inhibited cells proliferation of gastric cancer
Hyperbranched PEG-based multi-NHS polymer and bioconjugation with BSA
Star-shaped poly(ethylene glycol)-N-hydroxysuccinimide (star- PEG-NHS) has shown great promise in a variety of biomedical applications owing to its non-toxicity, innate non-immunogenic properties and versatile, multifunctional end groups. However, its complex and sophisticated synthetic methods, as well as high costs, have significantly impeded its wide application. Here, we report the design and synthesis of a hyperbranched PEG-based polymer with multiple NHS functional groups (>12). The hyper- branched PEG-based multi-NHS polymer can react easily with a protein (bovine serum albumin, BSA) to form a PEG-protein hydro- gel that displays great potential for biomedical applications
Treatment of Nutrient-rich Municipal Wastewater Using Mixotrophic Strain Chlorella kessleri GXLB-9
Growing algae on wastewaters offers a promising way for effective N and P recycling as well as low-cost algal biofuel feedstock accumulation. In this study, a locally isolated microalgae strain Chlorella kessleri GXLB-9 (C. kessleri GXLB-9), was evaluated for growth and nutrient removal efficiency grown in nutrient-rich wastewater centrifuged from activated sludge (NWCAS). And 3-(3, 4-dichlorophenyl)-1, 1-dimethyl urea (DCMU), one chemical that could block microalgae-based photosynthetic pathway, was used to evaluate the growth mode (autotrophy, heterotrophy or mixotrophy) of C. kessleri GXLB-9. The results showed that C. kessleri GXLB-9 was a facultative heterotrophic strain and 7-day batch cultivation idicated that the maximal removal efficiencies for total nitrogen, total phosphorus, and chemical oxygen demand (COD) were over 59%, 81%, and 88%, respectively, with high growth rate (0.490 d-1) and high biomass productivity (269 mg L-1 d-1). In addition, the impact of light-dark cycle on algae growth and nutrient removal was minimal while pH has significant impact on both algae growth and nutrient removal efficiency
Prognostic significance of XIAP and NF-κB expression in esophageal carcinoma with postoperative radiotherapy
A hybrid injectable hydrogel from hyperbranched PEG macromer as a stem cell delivery and retention platform for diabetic wound healing
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