Study of physical, chemical and consumer properties for development of dental gel basis aimed to cure of parodont diseases

The modern range of products for cure of parodont diseases is mostly represented by liquid medical forms (solutions, tinctures, liquid spirit extracts) and by ointments and gels. This article provides the results of the technology development of gel based on apple pectin. Physical, chemical and consumers properties of the gel were also studied in the framework of this articl

Polyphenolic Compounds Composition Study in Ocimum basilicum L. Herb and the Development of Their Quantification Assessment

The article demonstrates the study results of the garden basil chemical composition - Ocimum basilicum L. It is established that the basic polyphenols of a plant are hydroxycinnamic acids - rosemary, caftaric, chlorogenic. Flavonoids, the dominant of which is routine, are presented in smaller quantities. An optimal method for the quantitative determination of O. basilicum L. polyphenols is offere

Simplified mathematical modeling of the distribution process of licuroside and glycyram between the extractant and Glycyrrhizae radices

Theoretical development of the extraction process is an important task for further modeling and calculation of optimal conditions for extraction of biologically active compounds from the plant raw material. The aim of the study was to propose and test a theoretical model to describe the process of Licuroside and Glycyram distribution between the solid phase of Glycyrrhiza radices and the extractant. For studies, we used Glycyrrhiza radices (Liquorice roots). For extraction, we used plant raw material with particle size of 0.1-0.5 mm, and ethanol-water solution 70 % v/v was used as an extractan

Prospects for the use of Etafilcon a soft contact lenses and Betaxolol hydrochloride in the ophthalmic therapeutic system for treatment of glaucoma combined with myopia

In this article the short description of soft contact lenses materials in terms of their use in the ophthalmic therapeutic systems and experimental results of their adsorptive properties in combination with the ophthalmic solution of Betaxolol hydrochloride are presente

Development of the technology for obtaining a thick extract from fruits of milk thistle with the stage of ultrasonic influence

This article presents the results of the development of technology for obtaining a thick extract of milk thistle fruits using ultrasonic treatment of plant material and extractant in the soaking stage. Materials and Methods: For the research, crushed fruits of milk thistle from “Biokor” Ltd, Penza, Russia, series 011216 were used, and the shelf life is 2 year

The study of the chemical composition of sorption substances

The article presents a study of the chemical composition of sorption substances. The chemical composition is established, the main prevailing elements and impurities are revealed. The crystal-chemical structure of sorption substances is proposed. A comparative analysis of the chemical composition and the classification of sorption substances, depending on the origi

Study of sedative tea phytocomplex within the framework of studies aimed at creation of a rectal dosage form with antihistaminic effect

We designed a new complex drug with antiallergic effect containing, in addition to the main component loratadine, a phytocomplex for an extra therapeutic effect. A collection of plants with sedative activity is chosen and the optimal agent for extraction of bioactive compound

Study of antimicrobial activity and technology optimization of Calendulae flos galenicals

The article presents materials on optimization of manufacture technology for Calendulae flos galenicals with medium level of antibacterial activity. For antibacterial study of extracts, we used agar well diffusion method. In our research, we utilized six test-strain microorganisms: E. coli ATCC 25922, S. aureus ATCC 25923, P. vulgaris ATCC 4636, P. aeruginosa ATCC 27853, C. albicans ATCC 885/653, and B. subtilis ATCC 6633. We have found that the maximum level of extracts’ antimicrobial activity is achieved in the range of ethanol content in the extractant from 70 to 97 % v/

New approach to drug delivery in ophthalmological practice: development of composite ophthalmological solution for drug loading of soft contact lenses

The aim of the research is to develop the composition of the ophthalmic transport system for the treatment of glaucoma. Also, the proposed manufacturing algorithms were proposed for drug loading ophthalmological solution

An innovative way for extraction of essential oil components from Pimpinella Anisum L. fruits

The aim of this article was to test the hypothesis about the possibility for extraction of essential oil components from the plant raw material (PRM) by the example of Pimpinella anisum L. fruits with two different perfluoro organic solvents, Novec 1230 and Novec 710