Neural Contourlet Network for Monocular 360 Depth Estimation

For a monocular 360 image, depth estimation is a challenging because the distortion increases along the latitude. To perceive the distortion, existing methods devote to designing a deep and complex network architecture. In this paper, we provide a new perspective that constructs an interpretable and sparse representation for a 360 image. Considering the importance of the geometric structure in depth estimation, we utilize the contourlet transform to capture an explicit geometric cue in the spectral domain and integrate it with an implicit cue in the spatial domain. Specifically, we propose a neural contourlet network consisting of a convolutional neural network and a contourlet transform branch. In the encoder stage, we design a spatial-spectral fusion module to effectively fuse two types of cues. Contrary to the encoder, we employ the inverse contourlet transform with learned low-pass subbands and band-pass directional subbands to compose the depth in the decoder. Experiments on the three popular panoramic image datasets demonstrate that the proposed approach outperforms the state-of-the-art schemes with faster convergence. Code is available at https://github.com/zhijieshen-bjtu/Neural-Contourlet-Network-for-MODE.Comment: IEEE Transactions on Circuits and Systems for Video Technolog

Gentle Handling Attenuates Innate Defensive Responses to Visual Threats

Innate defensive responses to threats are essential for animal survival. The complexity and variability of innate defensive behaviors can be due to individual experiences, environmental factors, and internal states. However, it is not completely understood if the gentle handling involved in sensory processing affects innate defensive responses to visual threats. Here, we report attenuation of innate defensive responses after gentle handling accompanied by de-excitation of the intermediate layer (IL) and deep layer (DL) of the superior colliculus (SC) but not of the superficial layer (SL). Our theoretical analysis of the c-Fos network revealed an increased correlation in module 1, which maybe generally functionally associated with fear emotional, a decreased correlation in module 2, which maybe generally functionally associated with sensory processing. The IL of the SC appeared to have the highest correlation with the two modules. We verified the dynamic activities of the IL of SC in response to overhead looming stimulus using fiber photometry. Retrograde labeling of 18 regions of interest (ROIs) showed that the IL received significant inputs from the cortical areas, thalamus, hypothalamus, and brainstem. These data suggest the sensory processing involved in the modulatory roles of the SC in innate fear processing

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

CD4+CD25+Foxp3+ regulatory T cells (Tregs) accumulate in bone marrow microenvironment in acute myeloid leukemia (AML). However, little is known about how the tumor environment including tumor cells themselves affects this process. Here we demonstrated that AML cells expressed inducible T-cell costimulator ligand (ICOSL) that can provide costimulation through ICOS for the conversion and expansion of Tregs sustaining high Foxp3 and CD25 expression as well as a suppressive function. TNF-a stimulation up-regulated the expression of ICOSL. Furthermore, both the conversion and expansion of CD4+CD25+Foxp3+ T cells and CD4+ICOS+Foxp3+ T cells were induced by co-culture with AML cells overexpressed ICOSL. CD4+CD25+ICOS+ T cells possessed stronger ability to secrete IL-10 than CD4+CD25+ICOS− T cells. The mechanism by which IL-10 promoted the proliferation of AML cells was dependent on the activation of the Akt, Erk1/2, p38, and Stat3 signaling pathways. Blockade of ICOS signaling using anti-ICOSL antibody impaired the generation of Tregs and retarded the progression of an AML mice model injected with C1498 cells. The expression of ICOSL of patient AML cells and ICOS+ Tregs were found to be predictors for overall survival and disease-free survival in patients with AML, with ICOS+ Treg cell subset being a stronger predictor than total Tregs. These results suggest that ICOSL expression by AML cells may directly drive Treg expansion as a mechanism of immune evasion and ICOS+ Treg cell frequency is a better prognostic predictor in patients with AML

Extraction of Amorphous Silicon from Fly Ash and High Value Utilization of Silicon Products

Coal-based energy structure of China has not only guaranteed energy supply, but also brought a lot of fly ash, because of the low utilization rate of fly ash has caused serious environmental pollution and farmland occupation problems, especially in Northwest China. At present, the extraction of useful components has become a research hotspot of high-value utilization of fly ash, especially the extraction of amorphous silicon in it an important means to improve the value of resource utilization of fly ash. In this paper, two main processes of extracting amorphous silicon from fly a share described, namely alkali leaching and acid leaching. The principle and characteristics of the process are analyzed and the application of products by silicon extraction in the insulation material, silica black, molecular sieve, filling of paper and rubber is discussed. Compared with the products of traditional silicon-based, the various of silicon-based products prepared by fly ash have the advantages of better performance, lower cost and more wider application, which can be regarded as an effective way to realize the high-value, fine and cascade utilization of fly ash