7 research outputs found
The Effect of HOPSCA on Residential Property Values: Exploratory Findings from Wuhan, China
Mixed-use development is theoretically considered to enhance the residential value of an area. However, limited empirical research has focused on European and North American cities. HOPSCA is a real estate project that integrates hotels, offices, parks, shopping malls, conference centers, and apartments. As an important mixed-use development project in Chinese cities, HOPSCA is designed to improve the quality of urban life and to enhance the residential value of an area. Few studies have explicitly examined the effect of HOPSCA on residential property values, let alone linked this question to particular types of HOPSCA. To bridge this research gap, we selected Wuhan City in China as a case study to explore the effects of HOPSCA on residential property values. Specifically, we used the potential model to quantify the effects of HOPSCA and used the geographically weighted regression (GWR) method to estimate the relationship between HOPSCA variables and residential property values. The results are as follows: (1) the effects of HOPSCA on residential property values are statistically significant with positive and negative effects. The balanced-development HOPSCA generated the greatest effects, with the highest premium of 10.76% placed on residential properties. Moderate price premiums of 3.57% and 1.83% were generated under the influence of the commerce-oriented HOPSCA and housing-oriented HOPSCA, respectively. By contrast, the business-oriented HOPSCA exerted a negative effect on residential property (−2.43%). (2) Significant spatial heterogeneity exists on the effect of HOPSCA on residential property values. The results showed that the influence of different types of HOPSCA, viz. the higher the compatibility between the HOPSCA type and the socioeconomic context of Wuhan, the higher the premium captured by residential properties within the city areas. HOPSCA benefits the improvement of the quality of urban life, which promotes urban development. For policy makers and real estate developers, our findings suggest that matching the development types and the spatial layouts of HOPSCA with the regional socioeconomic contexts is critical for enhancing the value performance of such projects
Association between tumor necrosis factor alpha-238G/a polymorphism and tuberculosis susceptibility: a meta-analysis study
Abstract Background Tumor necrosis factor alpha (TNF-α) plays a key role in the containment of tuberculosis. The relationship between the TNF -238G/A polymorphism and tuberculosis susceptibility remains inconclusive. A comprehensive meta-analysis was made to provide a more precise estimate of the relationship between them. Methods Multiple search strategies were used. A fixed effect model was takentook to estimate pooled OR with 95% confidence interval (CI) for the association between the TNF -238G/A polymorphism and tuberculosis susceptibility. The Chi-squared-based Q-test and I-squaredI2 statistic were calculated to examine heterogeneity. Begg’s funnel plot and Egger’s test were used to assess publication bias. Results 9 case-control studies were included in this meta-analysis. No significant heterogeneity was demonstrated, and no obvious publication bias was detected among the included studies. The meta-analysis indicated that there was no significant association between the TNF -238G/A polymorphism and tuberculosis susceptibility (GA+AA versus GG model: OR=1.005, 95% CI: 0.765-1.319; A versus G model: OR=1.000, 95% CI: 0.769-1.300). In the subgroup analyses by ethnicity, types of TB and human immunodeficiency virus (HIV) status, no significant association were identified. Conclusions The meta-analysis involving 2723 subjects did not detect any association between the TNF -238G/A polymorphism and tuberculosis susceptibility.</p
Analysis of U-Shaped Steel Failure Characteristics in Rock Burst Roadway and Design of Stable Structure and Constant Resistance O-Shed
The U-shaped steel support has good surface protection and is one of the main supporting forms of the roadway under rock bursts. However, in the supporting process of roadways under rock burst, there are poor mechanical properties of lap joints, resulting in a serious decline in the anti-impact performance of U-shaped steel supports. Using a combination of laboratory experiments and theoretical analysis, we study the sliding mechanism of the U-shaped steel bracket’s overlap section bearing and find the key factors affecting the sliding performance of the overlap section. The characteristics of deformation and failure of U-shaped steel supports under impact loads are analyzed by numerical calculations. An improved method for optimizing the sliding performance of the lap section is proposed to provide theoretical support for the design of stable and constant-resistance energy-absorbing O-shed supports. The research results show that the frictional properties between the contact surfaces of the overlapped sections, especially the frictional properties between the contact surfaces of the clamp and the U-shaped steel, determine the sliding characteristics of the U-shaped steel overlapped sections, which are the key factors affecting the bearing capacity of the support. The single-point maximum bearing capacity of the U-shaped steel bracket under the uniformly distributed impact load is basically close to the maximum bearing capacity of the U-shaped steel bracket under the concentrated impact load. When the U-shaped steel bracket is uniformly loaded, its bearing capacity can be increased several times. When a gasket is added between the U-section steel and the clamping bolt in the lap section, the bearing capacity changes smoothly during the sliding process, which greatly improves the friction performance between the contact surfaces, and can greatly improve the overall bearing capacity, energy absorption, and anti-impact performance of the support structure. Based on this, a stable and constant energy-absorption O-type shed structure for the impacted underground roadway in Laohutai Mine was proposed. The field application proved that improving the sliding performance at the joint of the U-shaped steel support can effectively control the deformation of the roadway under the impact load