Effects of air pollution on neonatal prematurity in guangzhou of china: a time-series study

<p>Abstract</p> <p>Background</p> <p>Over the last decade, a few studies have investigated the possible adverse effects of ambient air pollution on preterm birth. However, the correlation between them still remains unclear, due to insufficient evidences.</p> <p>Methods</p> <p>The correlation between air pollution and preterm birth in Guangzhou city was examined by using the Generalized Additive Model (GAM) extended Poisson regression model in which we controlled the confounding factors such as meteorological factors, time trends, weather and day of the week (DOW). We also adjusted the co linearity of air pollutants by using Principal Component Analysis. The meteorological data and air pollution data were obtained from the Meteorological Bureau and the Environmental Monitoring Centre, while the medical records of newborns were collected from the perinatal health database of all obstetric institutions in Guangzhou, China in 2007.</p> <p>Results</p> <p>In 2007, the average daily concentrations of NO₂, PM₁₀and SO₂in Guangzhou, were 61.04, 82.51 and 51.67 μg/m³respectively, where each day an average of 21.47 preterm babies were delivered. Pearson correlation analysis suggested a negative correlation between the concentrations of NO₂, PM₁₀, SO_2,and temperature as well as relative humidity. As for the time-series GAM analysis, the results of single air pollutant model suggested that the cumulative effects of NO₂, PM₁₀and SO₂reached its peak on day 3, day 4 and day 3 respectively. An increase of 100 μg/m³of air pollutants corresponded to relative risks (RRs) of 1.0542 (95%CI: 1.0080 ~1.1003), 1.0688 (95%CI: 1.0074 ~1.1301) and 1.1298 (95%CI: 1.0480 ~1.2116) respectively. After adjusting co linearity by using the Principal Component Analysis, the GAM model of the three air pollutants suggested that an increase of 100 μg/m³of air pollutants corresponded to RRs of 1.0185 (95%CI: 1.0056~1.0313), 1.0215 (95%CI: 1.0066 ~1.0365) and 1.0326 (95%CI: 1.0101 ~1.0552) on day 0; and RRs of the three air pollutants, at their strongest cumulative effects, were 1.0219 (95%CI: 1.0053~1.0386), 1.0274 (95%CI: 1.0066~1.0482) and 1.0388 (95%CI: 1.0096 ~1.0681) respectively.</p> <p>Conclusions</p> <p>This study indicates that the daily concentrations of air pollutants such as NO₂, PM₁₀and SO₂have a positive correlation with the preterm births in Guangzhou, China.</p

Electron cyclotron heating assisted start-up experiments in J-TEXT

Electron cyclotron heating (ECH) breakdown and burn-through assist has been adopted to make the ITER start-up, which uses a low toroidal electric field of about 0.3 V/m, more robust. Related studies have been carried out on many fusion machines such as DIII-D, JT-60U, Tore Supra and FTU. However, the required ECH power to ensure an effective breakdown assist at ITER is not yet clear. Experiment was also performed in J-TEXT to determine the minimum ECH power requirements to assist breakdown and develop a better physics description of the process. The breakdown loop voltage for a successful shot was reduced from 34 to 3.7 V (corresponding to 0.56 V/m) by 300 kW X2-mode ECH power. The critical ECH power to assist the successful formation of a tokamak discharge is about 200kW, and below this value, ionization caused by ECH power is observed, however, the tokamak discharge start-up does not succeed. The effect of different loop voltages and ECH pulse-width on start-up was also studied. As injecting ECH power at a proper time, low ECH power can achieve a similar pre-ionization result as the case with high power. Extremely low breakdown voltage leads to a higher toroidal field later when putting a capacity to continue discharging in J-TEXT. The earlier shutdown of ECH power caused a failed discharge