DoubleHigherNet : coarse-to-fine precise heatmap bottom-up dynamic pose computer intelligent estimation

Accurate keypoint positioning is necessary for bottom-up multi-person pose estimation methods to handle scale variation and crowdedness. In this paper, we present DoubleHigherNet: a novel network learning scale-aware and precise heatmap representation for bottom-up process using double high-resolution feature pyramids and coarse-to-fine training. The two feature pyramids in DoubleHigherNet consists of 1/4 resolution feature and higher-resolution (1/2) maps generated by attention fusion blocks and transposed convolutions. Benefited by the training strategy, muti-resoltion and coarse-fine heatmap aggregation, the proposed approach is able to predict keypoints more accurately so as to perform better on difficult crowded scenes. DoubleHigherNetw32 achieves competitive result on CrowdPose-test, surpassing all the top-down methods and bottom-up SOTA HigherHRNet-w32 (which possesses similar number of params with DoubleHigherNet-w32)

A method for calculating permanent displacement of seismic-induced bedding rock landslide considering the deterioration of the structural plane

The mechanism of seismic-induced bedding rock landslide is distinct from that of slope instability/landslide in normal gravity conditions; their failure modes are mainly characterized by vibration deterioration effect of rock mass structural plane due to a seismic loading, which has a significant effect on the stability of the bedding rock landslide. Several advanced methods have been proposed to assess earthquake-induced bedding rock landslide. However, the quantitative evaluation of the vibration deterioration effect of structural plane, along with its application in the dynamic stability analysis of bedding rock slopes, remains a challenging topic that requires further study. In this study, on the basic of the analysis of the cyclic shear condition and the cyclic shear test of the structural plane, the expressions to calculate the dilatancy angle and basic friction angle of structural plane under cyclic shear loading are studied. A deterioration formula for structural plane shear strength is proposed, which fully considers the deterioration effect during cyclic shear. Furthermore, a new calculating method of the seismic-induced permanent displacement of the bedding rock landslide, which introduces the deterioration effect of the structural plane, is developed. A case study was used to compare the permanent displacement calculated with the proposed method with those obtained using the Newmark and Qi methods, which demonstrates the effectiveness and applicability of the proposed method

Numerical simulation of diagenetic evolution and porosity prediction in eastern area of Wushi Sag

The commercial oil fields discovered in the eastern area of Wushi Sag in recent years are mainly formed in a complex continental sedimentary environment, which was influenced by the tectonic movement, sedimentation and diagenesis.The reservoir in the oilfields of the study is characterized by a strong heterogeneity, complex reservoir seepage mechanism, which affects the development program Therefore, the analysis of the main controlling factors of the reservoir physical properties is extremely necessary, which can help the decision-makers to predict the sweet spot area theoretically and technically.In this paper, the method of numerical simulation of diagenetic evolution was adopted, in which the diagenesis index was obtained by the simulation of vitrinite reflectance, paleotemperature, smectite content in illite/smectite mixed layer, and quartz autogenesis increase based on the diagenetic environment parameter and chemical kinetic model.Moreover, the diagenetic stage and the lateral distribution of porosity were predicted based on the change of the diagenetic index.The results show that the diagenesis stage in the eastern area of Wushi Sag is the middle diagenesis stage A1-A2, and the diagenesis in the central sag is strong and gradually weaken.Combining the understanding of sedimentary and diagenesis, establishing the porosity prediction model and predicting it in horizon, the results indicate that: Following the source of sedimentary, the reservoir physical properties worsen with increasing burial depth, which is consistent with the change trend of diagenesis

Effect of Polyethylene Glycol on Preparation of Magnesium Hydroxide by Electrodeposition

The current research focuses on the mechanism of the surfactant polyethylene glycol (PEG) in the preparation of magnesium hydroxide by electrolysis of a salt lake bischite aqueous solution. The samples were analyzed by a scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared spectrometer (FT-IR) and laser particle size analyzer. The characterization results show that PEG plays an important role in adjusting the growth mode and morphology of Mg(OH)2 crystals. The ether group of the PEG molecular chain and the hydroxyl group of Mg(OH)2 can be combined by a hydrogen bond, which provides a "template" for the growth of Mg(OH)2. At the same time, the difference in growth mode and morphology will also affect the economic performance of electrolytic reactions. When the PEG content reaches 0.4 g/L, the particle size of the product is uniform, which can well reduce the polarization of the electrode plate. The cell potential of electrolytic reaction is small, and the economic benefit is high. When the content of PEG is low, it has a low impact on the product and the economic benefits of electrolytic reaction. When the PEG content is higher than 0.4 g/L, the electrode reaction is hindered, resulting in an increase in cell potential

A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability

Abstract Liver cancer stem cells (LCSCs) are recognized as key contributors to hepatocarcinogenesis, progression, and recurrence. Consequently, eradicating LCSCs has a great chance of increasing long-term survival in patients with liver cancer. Parthenolide (PTL), a natural sesquiterpene lactone product, possesses robust antitumor activity. However, the effects of PTL on LCSCs and underlying mechanisms remain unknown. Here we show that administration of PTL stimulated cell cycle arrest at the G1 phase, induced apoptosis, and decreased the stemness of LCSCs. Further research indicates that PTL caused the production of ROS and the reduction of oxidative phosphorylation (OXPHOS) and mitochondrial membrane potential (MMP) levels of LCSCs. RNA sequencing (RNA-Seq) further shows that PTL decreased SLC25A1 expression at the mRNA level and that inhibition of SLC25A1 synergistically decreased the expression of IDH2 and several pivotal genes involved in mitochondrial respiratory chain complex, resulting in the production of ROS and mitochondrial dysfunction. In addition, the inhibitory effect of PTL on mitochondrial function and self-renewal capacity of LCSCs was abolished by the knockdown of SLC25A1 or treatment with SLC25A1 inhibitor CTPI-2. Importantly, PTL prevented liver cancer growth in vivo without clearly causing toxicity. Our research shows that PTL inhibits the growth and stemness of LCSCs through SLC25A1-mediated mitochondrial function. PTL may be a potential candidate natural agent for liver cancer treatment

Spatial waveguide mode separation for acoustic waves in a meta-slab composed of subunits with graded thicknesses

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Beam splitting of flexural waves with a coding meta-slab

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