X(3915) and X(4350) as new members in P-wave charmonium family

The analysis of the mass spectrum and the calculation of the strong decay of P-wave charmonium states strongly support to explain the newly observed X(3915) and X(4350) as new members in P-wave charmonium family, i.e., $\chi_{c0}^\prime$ for X(3915) and $\chi_{c2}^{\prime\prime}$ for X(4350). Under the P-wave charmonium assignment to X(3915) and X(4350), the $J^{PC}$ quantum numbers of X(3915) and X(4350) must be $0^{++}$ and $2^{++}$ respectively, which provide the important criterion to test P-wave charmonium explanation for X(3915) and X(4350) proposed by this letter. The decay behavior of the remaining two P-wave charmonium states with the second radial excitation is predicted, and experimental search for them is suggested.Comment: 4 pages, 2 figures, 2 tables. More references and discussions added, typos corrected. Accepted for publication in Phys. Rev. Lett

Design and Synthesis of Novel Anticancer Peptide Nanoparticles

Cancer has now become a common disease affecting human health. Existing cancer treatment drugs can no longer meet the growing needs of cancer patients, and the emergence of anticancer drug resistance has exacerbated this phenomenon. By designing and synthesizing new anticancer peptide nanoparticles and studying their anticancer effects, new strategies for cancer treatment may be obtained. Novel anticancer peptides are synthesized by adding basic amino acids and solid-phase synthesis technology, and their structural information is determined by mass spectrometry. Nanoparticles of anticancer peptide were synthesized by nano-self-assembly technology. Two novel anticancer peptides exhibited anticancer activity, one of which was assembled into nanoparticles. The theoretical isoelectric points of the modified SZG3 and SZG5 are all greater than physiological pH, and will be positively charged under physiological conditions. The estimated half-life of SZG3 and SZG5 is significantly extended (30h), which is beneficial to increase the efficacy and reduce toxic and side effects. SZG3 and SZG5 have a good inhibitory effect on tumor cells and have low toxicity to normal cells. Keywords: anticancer peptide, study, design, cancer, nanoparticles&nbsp