Association of polymorphic markers rs243865 and rs3025058 with the development of arterial hypertension

Association of polymorphic markers rs243865 and rs3025058 with the development of arterial hypertension Essential hypertension is a multifactorial polygenic disease with a highest incidence in the world. The purpose of the study was to assess the relationship between gene polymorphisms MMP2-1586S>T (rs243865) and -1612 5A/6A MMP3 (rs3025058) with the development of arterial hypertension in population of the Central Chernozem region of Russi

Analysis of the influence of chronic heart failure type on changes in the microelement composition of myocardial tissue in patients of senile age

Aim: conduct a comparative analysis of the content and distribution of macroelements (Ca2+, K+, Mg2+, and Na+) in myocardial tissue according to autopsy data in elder patients with CHF, depending on the LV E

Pharmacotherapy for the prevention of the progression of chronic heart failure in elderly patients with coronary heart disease

Aim: chronic heart failure (CHF), which occurs as a result of common cardiovascular diseases in the elderly, combined with age-related changes in both structural and functional features of the heart. Myocardial remodeling is an essential substrate that determines the occurrence and progression of CHF in elderly patient

Studying the gut virome in the metagenomic era:challenges and perspectives

The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of humangut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review, we focus on what is known about the role of bacteriophages in human health and the technical challenges involved in studying the gut virome, of which they are a major component. Lastly, we discuss what can be learned from studies of bacteriophages in other ecosystems

The measurement of adhesion forces in the system «cell-cell» by using atomic force microscope

The study shows the need to develop effective measures for the organization of medical and psychological rehabilitation of cardiovascular Rescuer

Analysis of dynamics of antibiotic resistance of pathogens in patients with diabetic foot syndrome undergoing in-patient treatment

In this paper we discuss the approaches to the choice of antibiotic therapy, subject to the sensitivity of these microorganisms to antibiotic therapy in the surgical department of St. Joseph Belgorod Regional Clinical Hospital. The obtained data state that III-IV generation pseudomonas cephalosporins and fluoroquinolones can be used for empirical therap

Experimental approaches to the assessment of potential cardioprotective means with doxorubicin-associated cardiomyopathy

Development of methodological approaches for evaluation of cardioprotective activity of drugs in doxorubicin cardiomyopath

Matrix Models of Resource Selection Strategy in Crisis Management

The article considers the formation of the matrix material sourcing strategies and how to use them to determine more appropriate management decisions in a crisis management

The risks of developing adverse outcomes according to geriatric status in patients with coronary heart disease with plannedaorto-coronary artery bypass grafting

The article assesses the risks of developing adverse outcomes in patients with coronary heart disease who underwent planned aorto-coronary artery bypass grafting according to geriatric status using such scales as the cardiovascular health study frailt