A Novel Narrowband Active Noise Control System with Online Secondary Path Modeling Based on Factor Decomposition and Application in Open Space

Due to the complexity of the coupling between the active noise control (ANC) controller and secondary path estimator, performance analysis of the system becomes particularly difficult. At present, the performance analysis of the system is often based on the fact that the secondary path tends to be stable, and the secondary path fitting error is minimal. However, in the early stage of system operation, or when the secondary path changes suddenly, the secondary path fitting error is significant, which easily causes divergence of the system control. It is still unable to guarantee the step-size bounds of convergence stability. Therefore, factor decomposition was used to analyze the mean weight behavior in this study. This strategy emphasizes the influence of secondary path modeling (SPM) error. The mean square behavior was evaluated using the energy conservation relationship. According to the established theoretical model, the convergence condition of the system was derived and the upper bound of step size suitable for all stages of system operation was obtained. The simulation and experimental results show that the ANC system is quite stable and robust under extreme conditions and has an obvious noise reduction effect in a specific range of open space, which can reach about 20 dB noise reduction

Mathematical Programming Model on Joint and Recovery of Paper Scrap

The joint and recovery of paper scrap was an optimal matching issue. The automatic restoration technology for the broken document was designed according to different cutting ways of the paper shredder. As the fragment data was an one-side print file, a nonlinear programming model with no constraint conditions was established for the straight-cutting broken paper scrap from a given print file of the same page, and the nonlinear programming model with restraint programming model was established for the broken scrap with straight cut and cross cut. For the paper scrap data from a one-page print file in English printed on both sides, the joint was accomplished by the ant colony algorithm

Identification of m6A-associated autophagy genes in non-alcoholic fatty liver

Background Studies had shown that autophagy was closely related to nonalcoholic fat liver disease (NAFLD), while N6-methyladenosine (m6A) was involved in the regulation of autophagy. However, the mechanism of m6A related autophagy in NAFLD was unclear. Methods The NAFLD related datasets were gained via the Gene Expression Omnibus (GEO) database, and we also extracted 232 autophagy-related genes (ARGs) and 37 m6A. First, differentially expressed ARGs (DE-ARGs) and differentially expressed m6A (DE-m6A) were screened out by differential expression analysis. DE-ARGs associated with m6A were sifted out by Pearson correlation analysis, and the m6A-ARGs relationship pairs were acquired. Then, autophagic genes in m6A-ARGs pairs were analyzed for machine learning algorithms to obtain feature genes. Further, we validated the relationship between feature genes and NAFLD through quantitative real-time polymerase chain reaction (qRT-PCR), Western blot (WB). Finally, the immuno-infiltration analysis was implement, and we also constructed the TF-mRNA and drug-gene networks. Results There were 19 DE-ARGs and four DE-m6A between NAFLD and normal samples. The three m6A genes and five AGRs formed the m6A-ARGs relationship pairs. Afterwards, genes obtained from machine learning algorithms were intersected to yield three feature genes (TBK1, RAB1A, and GOPC), which showed significant positive correlation with astrocytes, macrophages, smooth muscle, and showed significant negative correlation with epithelial cells, and endothelial cells. Besides, qRT-PCR and WB indicate that TBK1, RAB1A and GOPC significantly upregulated in NAFLD. Ultimately, we found that the TF-mRNA network included FOXP1-GOPC, ATF1-RAB1A and other relationship pairs, and eight therapeutic agents such as R-406 and adavosertib were predicted based on the TBK1. Conclusion The study investigated the potential molecular mechanisms of m6A related autophagy feature genes (TBK1, RAB1A, and GOPC) in NAFLD through bioinformatic analyses and animal model validation. However, it is critical to note that these findings, although consequential, demonstrate correlations rather than cause-and-effect relationships. As such, more research is required to fully elucidate the underlying mechanisms and validate the clinical relevance of these feature genes

Application of radiomics-based multiomics combinations in the tumor microenvironment and cancer prognosis

Abstract The advent of immunotherapy, a groundbreaking advancement in cancer treatment, has given rise to the prominence of the tumor microenvironment (TME) as a critical area of research. The clinical implications of an improved understanding of the TME are significant and far-reaching. Radiomics has been increasingly utilized in the comprehensive assessment of the TME and cancer prognosis. Similarly, the advancement of pathomics, which is based on pathological images, can offer additional insights into the panoramic view and microscopic information of tumors. The combination of pathomics and radiomics has revolutionized the concept of a “digital biopsy”. As genomics and transcriptomics continue to evolve, integrating radiomics with genomic and transcriptomic datasets can offer further insights into tumor and microenvironment heterogeneity and establish correlations with biological significance. Therefore, the synergistic analysis of digital image features (radiomics, pathomics) and genetic phenotypes (genomics) can comprehensively decode and characterize the heterogeneity of the TME as well as predict cancer prognosis. This review presents a comprehensive summary of the research on important radiomics biomarkers for predicting the TME, emphasizing the interplay between radiomics, genomics, transcriptomics, and pathomics, as well as the application of multiomics in decoding the TME and predicting cancer prognosis. Finally, we discuss the challenges and opportunities in multiomics research. In conclusion, this review highlights the crucial role of radiomics and multiomics associations in the assessment of the TME and cancer prognosis. The combined analysis of radiomics, pathomics, genomics, and transcriptomics is a promising research direction with substantial research significance and value for comprehensive TME evaluation and cancer prognosis assessment

Prediction of Fine Particulate Matter Concentration near the Ground in North China from Multivariable Remote Sensing Data Based on MIV-BP Neural Network

Rapid urbanization and industrialization lead to severe air pollution in China, threatening public health. However, it is challenging to understand the pollutants’ spatial distributions by relying on a network of ground-based monitoring instruments, considering the incomplete dataset. To predict the spatial distribution of fine-mode particulate matter (PM2.5) pollution near the surface, we established models based on the back propagation (BP) neural network for PM2.5 mass concentration in North China using remote sensing products. According to our predictions, PM2.5 mass concentrations are affected by changes in surface reflectance and the dominant particle size for different seasons. The PM2.5 mass concentration predicted by the seasonal model shows a similar spatial pattern (high in the east but low in the west) influenced by the terrain, but shows high value in winter and low in summer. Compared to the ground-based data, our predictions agree with the spatial distribution of PM2.5 mass concentrations, with a mean bias of +17% in the North China Plain in 2017. Furthermore, the correlation coefficients (R) of the four seasons’ instantaneous measurements are always above 0.7, indicating that the seasonal models primarily improve the PM2.5 mass concentration prediction

Precipitable Water Vapor Retrieval Based on DPC Onboard GaoFen-5 (02) Satellite

GaoFen-5 (02) (GF5-02) is a new Chinese operational satellite that was launched on 7 September 2021. The Directional Polarimetric Camera (DPC) is one of the main payloads and is mainly used for the remote sensing monitoring of atmospheric components such as aerosols and water vapor. At present, the DPC is in the stage of on-orbit testing, and no public DPC precipitable water vapor (PWV) data are available. In this study, a PWV retrieval algorithm based on the spectral characteristics of DPC data is developed. The algorithm consists of three parts: (1) the construction of the lookup table, (2) the calculation of water vapor absorption transmittance (WVAT) in the band at 910 nm, and (3) DPC PWV retrieval. The global PWV results derived from DPC data are spatially continuous, which can illustrate the global distribution of water vapor content well. The validation based on the Aerosol Robotic Network (AERONET) PWV data shows that the DPC PWV data have accuracy similar to that of Moderate-resolution Imaging Spectroradiometer (MODIS) PWV data, with coefficient correlation of determination (R2), mean absolute error (MAE), and relative error (RE) of 0.32, 0.30, and 0.93 using the DPC and 0.23, 0.36, and 0.96 using the MODIS, respectively. The results show that our proposed DPC PWV retrieval algorithm is feasible and has high accuracy. By analyzing the errors, we found that the calibration coefficients of the DPC in the 865 nm and 910 nm bands need to be updated

A Comprehensive Analysis of Ultraviolet Remote Sensing for Aerosol Layer Height Retrieval from Multi-Angle Polarization Satellite Measurements

Based on the optimal estimation (OE) theory and information content analysis method, we discuss the ability to include the multi-angle satellite ultraviolet polarization channel to retrieve the aerosol layer height (ALH) for ten typical aerosol types in the China region. We also quantitatively evaluate the effects of polarization measurements and the number of viewing angles on ALH retrieval under different conditions (aerosol model, aerosol optical depth, etc.). By comparing the different degree of freedom for signal (DFS) results of ALH caused by the theoretical retrieval error changes in different microphysical parameters in the aerosol and surface model, we identify the key factors affecting ALH retrieval. The results show that the extended ultraviolet band provides important information for ALH retrieval and is closely related to the scattering and absorption characteristics of aerosol models. The polarization measurements in fine mode reduce the posterior error of ALH retrieval by 6–39%; however, this is relatively small for coarse mode. In particular, when it is applied to the transported dust and background dust aerosol types, the posterior error is only reduced by 1–8% after adding polarization measurements. For these two aerosol types with weak absorption at the ultraviolet band, increasing the number of angles observed in addition to increasing the polarization channel will more effectively improve ALH inversion. Compared with other aerosol and surface model parameters, the retrieval errors for the total volume column, effective variance, real part of the complex refractive index, and surface reflectance are the main factors affecting ALH retrieval. Therefore, reducing the theoretical retrieval error of these parameters will be helpful