36 research outputs found
Structural Optimization Design of Large Wind Turbine Blade considering Aeroelastic Effect
This paper presents a structural optimization design of the realistic large scale wind turbine blade. The mathematical simulations have been compared with experimental data found in the literature. All complicated loads were applied on the blade when it was working, which impacts directly on mixed vibration of the wind rotor, tower, and other components, and this vibration can dramatically affect the service life and performance of wind turbine. The optimized mathematical model of the blade was established in the interaction between aerodynamic and structural conditions. The modal results show that the first six modes are flapwise dominant. Meanwhile, the mechanism relationship was investigated between the blade tip deformation and the load distribution. Finally, resonance cannot occur in the optimized blade, as compared to the natural frequency of the blade. It verified that the optimized model is more appropriate to describe the structure. Additionally, it provided a reference for the structural design of a large wind turbine blade
Comparative Analysis of the Microbial Profiles in Supragingival Plaque Samples Obtained From Twins With Discordant Caries Phenotypes and Their Mothers
Early childhood caries (ECC), the most frequent disease of oral cavity in preschool children, is the consequence of microbial, genetic, biochemical, socioeconomic, physical, environmental and health-influencing behavioral factors. To investigate the role of the oral microbiome and the impact of host and environmental factors in the occurrence and development of ECC, we studied the supragingival plaques of 14 twin pairs and a set of triplets with discordant caries phenotypes and 15 mothers, applying the Human Oral Microbe Identification using Next Generation Sequencing technique (HOMINGS). A total of 2,293,650 reads revealed 11 phyla, 116 genera, and 139 species of micromiome. Comparative analysis between the caries and caries-free group at species level revealed that the relative abundance of Streptococcus mutans, Lactobacillus fermentum, Actinomyces islaelii, Neisseria sica, and Veilonella dispar was much higher in caries group (P < 0.0001). Furthermore, monozygotic twins exhibited a higher degree of similarity than dizygotic twins. Finally, we analyzed the relationship between environmental factors and the oral microbiome, and our results indicat that the frequency of taking sweet food is associated with ECC. We conclude the following. First, the occurrence of Streptococcus mutans, Lactobacillus fermentum, Neisseria sica, and Veilonella dispar is strongly associated with the occurrence of ECC. Second, host genetic factors influence the oral microbiome composition, while environmental and behavioral factors like the frequency of taking sweet foods have an impact on the distribution of caries-related bacteria
Label-Free LSPR-Vertical Microcavity Biosensor for On-Site SARS-CoV-2 Detection
Cost-effective, rapid, and sensitive detection of SARS-CoV-2, in high-throughput, is crucial in controlling the COVID-19 epidemic. In this study, we proposed a vertical microcavity and localized surface plasmon resonance hybrid biosensor for SARS-CoV-2 detection in artificial saliva and assessed its efficacy. The proposed biosensor monitors the valley shifts in the reflectance spectrum, as induced by changes in the refractive index within the proximity of the sensor surface. A low-cost and fast method was developed to form nanoporous gold (NPG) with different surface morphologies on the vertical microcavity wafer, followed by immobilization with the SARS-CoV-2 antibody for capturing the virus. Modeling and simulation were conducted to optimize the microcavity structure and the NPG parameters. Simulation results revealed that NPG-deposited sensors performed better in resonance quality and in sensitivity compared to gold-deposited and pure microcavity sensors. The experiment confirmed the effect of NPG surface morphology on the biosensor sensitivity as demonstrated by simulation. Pre-clinical validation revealed that 40% porosity led to the highest sensitivity for SARS-CoV-2 pseudovirus at 319 copies/mL in artificial saliva. The proposed automatic biosensing system delivered the results of 100 samples within 30 min, demonstrating its potential for on-site coronavirus detection with sufficient sensitivity
Energy Solutions for Wearable Sensors: A Review
Wearable sensors have gained popularity over the years since they offer constant and real-time physiological information about the human body. Wearable sensors have been applied in a variety of ways in clinical settings to monitor health conditions. These technologies require energy sources to carry out their projected functionalities. In this paper, we review the main energy sources used to power wearable sensors. These energy sources include batteries, solar cells, biofuel cells, supercapacitors, thermoelectric generators, piezoelectric and triboelectric generators, and radio frequency (RF) energy harvesters. Additionally, we discuss wireless power transfer and some hybrids of the above technologies. The advantages and drawbacks of each technology are considered along with the system components and attributes that make these devices function effectively. The objective of this review is to inform researchers about the latest developments in this field and present future research opportunities
Optimization Method for Girder of Wind Turbine Blade
This paper presents a recently developed numerical multidisciplinary optimization method for design of wind turbine blade. The objective was the highest possible blade weight under specified atmospheric conditions, determined by the design giving girder layer and location parameter. Wind turbine blade on box-section beams girder is calculated by ply thickness, main girder and trailing edge. In this study, a realistic 30 m blade from a 1.2 MW wind turbine model of blade girder parameters is established. The optimization evolves a structure which transforms along the length of the blade, changing from a design with spar caps at the maximum thickness and a trailing edge mass to a design with spar caps toward the tip. In addition, the cross-section structural properties and the modal characteristics of a 62 m rotor blade were predicted by the developed beam finite element. In summary, these findings indicate that the conventional structural layout of a wind turbine blade is suboptimal under the static load conditions, suggesting an opportunity to reduce blade weight and cost
Multistep Wind Speed Forecasting Based on a Hybrid Model of VMD and Nonlinear Autoregressive Neural Network
Reducing the costs of wind power requires reasonable wind farm operation and maintenance strategies, and then to develop these strategies, the 24-hour ahead forecasting of wind speed is necessary. However, existing prediction work is mostly limited to 5 hours. This work developed a diurnal forecasting methodology for the regional wind farm according to real-life data of the supervisory control and data acquisition (SCADA) system of a wind farm from Jiangxi Province. The methodology used the variational mode decomposition (VMD) to extract wind characteristics, and then, the characteristics were put in the nonlinear autoregressive neural network (Narnet) and long short-term memory network (LSTM) for prediction; the forecast results of VMD-Narnet and VMD-LSTM are compared with the actual wind speed. The comparison results indicate that compared with the LSTM, the Narnet improves the accuracy by 61.90% in 24 hours on wind speed forecasting, and the predicted time horizon was improved by 6.8 hours. This work strongly supports the development of wind farm operation and maintenance strategies and provides a foundation for the reduction of wind power costs
Label-Free LSPR-Vertical Microcavity Biosensor for On-Site SARS-CoV-2 Detection
Cost-effective, rapid, and sensitive detection of SARS-CoV-2, in high-throughput, is crucial in controlling the COVID-19 epidemic. In this study, we proposed a vertical microcavity and localized surface plasmon resonance hybrid biosensor for SARS-CoV-2 detection in artificial saliva and assessed its efficacy. The proposed biosensor monitors the valley shifts in the reflectance spectrum, as induced by changes in the refractive index within the proximity of the sensor surface. A low-cost and fast method was developed to form nanoporous gold (NPG) with different surface morphologies on the vertical microcavity wafer, followed by immobilization with the SARS-CoV-2 antibody for capturing the virus. Modeling and simulation were conducted to optimize the microcavity structure and the NPG parameters. Simulation results revealed that NPG-deposited sensors performed better in resonance quality and in sensitivity compared to gold-deposited and pure microcavity sensors. The experiment confirmed the effect of NPG surface morphology on the biosensor sensitivity as demonstrated by simulation. Pre-clinical validation revealed that 40% porosity led to the highest sensitivity for SARS-CoV-2 pseudovirus at 319 copies/mL in artificial saliva. The proposed automatic biosensing system delivered the results of 100 samples within 30 min, demonstrating its potential for on-site coronavirus detection with sufficient sensitivity
Acid-resistant genes of oral plaque microbiome from the functional metagenomics
Acid resistance is one of key properties assisting the survival of cariogenic bacteria in a dental caries environment, but only a few genes conferring acid resistance have been identified to data. Functional metagenomics provides a systematic method for investigating commensal DNA to identify genes that encode target functions. Here, the host strain Escherichia coli DH10B and a constructed bidirectional transcription vector pSKII+-lacZ contributed to the construction of a metagenomic library, and 46.6 Mb of metagenomic DNA was cloned from carious supragingival plaque of 8children along with screening for lethal functionality. The screen identified 2 positive clones that exhibited a similar aciduric phenotype to that of the positive controls. Bioinformatic analysis revealed that these two genes encoded an ATP/GTP-binding protein and a malate dehydrogenase. Moreover, we also performed functional screening of Streptococcus mutans, since it is one of the predominant cariogenic strains but was not identified in our initial screening. Five positive clones were retrieved. In conclusion, our improved functional metagenomics screening method helped in the identification of important acid resistance genes, thereby providing new insights into the mechanism underlying caries formation as well as in the prevention and treatment of early childhood caries (ECC)
Research on semi-active vibration isolation system based on electromagnetic spring
This paper proposes a semi-active variable stiffness vibration isolation system based on electromagnetic spring for the low-frequency vibration isolation of mass-varying objects. It is achieved by four straight leaf springs in parallel to an electromagnetic spring system composed of a single electromagnet and a permanent magnet. The equivalent magnetic circuit method is used to compute electromagnetic force of the electromagnetic spring system, and mathematical model of the semi-active vibration isolation system is established according to Maxwell's equations. The nonlinear mathematical model is linearized at the equilibrium point by using the Taylor series expansion theorem to establish linear state-space representation of the system, and then using the traditional PID control method, a double closed-loop feedback control system of the inner current loop and outer location loop is designed. By controlling the current in the coil, the equivalent stiffness and electromagnetic force of the system are variable to achieve semi-active control. Furthermore, the control block diagram of the semi-active vibration isolation system is built based on Simulink software, then make a simulation analysis to the vibration isolation performance of the system and compare the effects of vibration isolation with inner current loop control and without inner current loop control, respectively. Finally, the experiments prove the correctness of the theory. It concludes that this semi-active vibration isolation system is a vibration isolation system with broad application prospects, which has fast current response, high vibration isolation efficiency, and an excellent vibration isolation effect for the low-frequency disturbance of mass-varying objects