sj-pdf-2-sci-10.1177_00368504231220765 - Supplemental material for A puzzling case report of well-differentiated neuroendocrine tumor mixed with gastric adenocarcinoma of the fundic gland type associated with autoimmune gastritis

Supplemental material, sj-pdf-2-sci-10.1177_00368504231220765 for A puzzling case report of well-differentiated neuroendocrine tumor mixed with gastric adenocarcinoma of the fundic gland type associated with autoimmune gastritis by Zheng Wang, Weixun Zhou, Jingnan Li, Wenlong Wen, Zhiyong Liang and Zhen Huo in Science Progress</p

sj-pdf-3-sci-10.1177_00368504231220765 - Supplemental material for A puzzling case report of well-differentiated neuroendocrine tumor mixed with gastric adenocarcinoma of the fundic gland type associated with autoimmune gastritis

Supplemental material, sj-pdf-3-sci-10.1177_00368504231220765 for A puzzling case report of well-differentiated neuroendocrine tumor mixed with gastric adenocarcinoma of the fundic gland type associated with autoimmune gastritis by Zheng Wang, Weixun Zhou, Jingnan Li, Wenlong Wen, Zhiyong Liang and Zhen Huo in Science Progress</p

Overall survival of the 23 PMEC patients with follow-up.

<p>(A) OS according to age. (B) OS according to growth pattern. (C) OS according to tumor diameter. (D) OS according to tumor grade. (E) OS according to Ki-67 labeling index. (F) OS according to surgical resection.</p

List of 16 exons of 7 genes in the present study.

<p>List of 16 exons of 7 genes in the present study.</p

FISH analysis.

<p>(A) The MAML2 gene is rearranged in PMEC and shows a disruption of the red and green signals (x1000, oil immersion). (B) The MAML2 gene is not rearranged in MEC-like pulmonary carcinoma and only shows overlapping yellow or green/red fusion signals (x1000, oil immersion). (C) TheALK gene is rearranged in MEC-like pulmonary carcinoma and shows a disruption of the red and green signals (x1000, oil immersion).</p

Immunostains of MEC-like pulmonary carcinoma.

<p>(A) P63 was positive in some cells in the same case in 2A (x150). (B) TTF-1 was positive in some cells in the same case in 2A (x150). (C) p63 was positive in some cells in the same case in 2B (x150). (D) TTF-1 was positive in some cells in the same case in 2B (x150). (E) p63 was positive in some cells in the same case in 2C (x150). (F) TTF-1 was positive in some cells in the same case in 2C (x150). (G) ALK was positive in tumor cells as the same case in 2C (x150). (H) ALK was positive in some tumor cells as the same case in 2D (x150).</p

Pathological features of 26 patients with pulmonary mucoepidermoid carcinoma.

<p>Pathological features of 26 patients with pulmonary mucoepidermoid carcinoma.</p

Microscopic images of MEC-like pulmonary carcinoma.

<p>(A) Case 1 showing solid nests in the left upper corner and mucin-filled cysts and mucous cells on the right side (H&E, x75). (B) Case 2 showing many mucous cells in the solid nests (H&E, x150). (C) Case 3 showing a cribriform-like structure with mucous cells (H&E, x150). (D) Case 4 was a mucoepidermoid carcinoma-like adenosquamous carcinoma (H&E, x150) (the illustration in the lower right corner clearly shows keratinization).</p

Clinicopathological, immunohistochemical, and fluorescence in situ hybridization data of 8 patients with mucoepidermoid carcinoma-like pulmonary carcinoma.

<p>^# Scanty</p><p>Clinicopathological, immunohistochemical, and fluorescence in situ hybridization data of 8 patients with mucoepidermoid carcinoma-like pulmonary carcinoma.</p

List of various antibody markers in the present study.

<p>List of various antibody markers in the present study.</p