New methods to detect early manifestations of adverse side effects of glucocorticosteroids in children

The article focuses on the early manifestations of adverse side effects in children with nephrotic syndrome receiving glucocorticosteroids. The search for criteria of early side effect manifestations is a real challenge nowadays. The authors developed new diagnostic criteria for early detection of pharmacotherapeutical side effects in children with nephrotic syndrom

Characteristics of adverse side effects of corticosteroid therapy in children with nephrotic syndrome and methods of pharmacological correction

The article discusses the issues of the long-term glucocorticosteroid therapy in children with nephrotic syndrome that results in severe adverse side effect

On The 100th Anniversary Of The Founder Of The Odessa Scientific School Of Economic Thought A. K. Pokrytan

The partnership between the Odessa National University of Economics and "D. A. Tsenov” Academy of Economics is an example of a successful model for adding value in the field of scientific research. With its annual scientific conferences, the Odessa National University of Economics has provided dozens of scientists from the Svishtov Academy and other foreign researchers with the opportunity to publish their papers abroad. Prof. Mihail Zveryakov himself is a Doctor Honoris Causa (Zastrahovatel.com, 2010) of D. A. Tsenov Academy and a prominent co-author in collaborative research publications indexed in SCOPUS Q1/WoS (Zahariev, et al., 2020). The paper commemorates and pays due respect to Prof. Anatoly Karpovich Pokrytan - one of the most prominent scientists in the field of economics whose centenary provided his scientific followers with the opportunity to reflect on his scientific legacy. The 100th anniversary of the establishment of the Odessa National Economic University in Ukraine (founded under the name Odessa Institute of National Economy) on 16 May 1921 is another evidence for our Ukrainian partner’s tenacity during the decades of intense socio-economic and ideological changes of the 20th and the 21st century

GENETIC POLYMORPHISM OF MYCOBACTERIUM TUBERCULOSIS IN PATIENTS WITH TUBERCULOSIS AND HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN EASTEN SIBERIA

A total 61 randomly selected strains of M. tuberculosis were genotyped by the 12 loci of MIRU-VNTR. It was shown the predominance of the Beijing genetic group (78,4 %) in population of mycobacterium from the patients with tuberculosis and. human immunodeficiency virus infection in Irkutsk region and. Buryatia. Multidrug resistance was observed in 34,4 % of the studied strains without significant differences among representatives of Beijing and non-Beijing

Preparation Of ZnS Thin Films by the Chemical Bath Deposition Method

The work was financially supported by program 211 of the Government of the Russian Federation (№ 02.A03.21.0006)

Long-term variability of the optical spectra of NGC 4151: I. Light curves and flux correlations

Results of a long-term spectral monitoring of the active galactic nucleus of NGC 4151 are presented (11 years, from 1996 to 2006). High quality spectra (S/N>50 in the continuum near Halpha and Hbeta) were obtained in the spectral range ~4000 to 7500 \AA, with a resolution between 5 and 15 A, using the 6-m and the 1-m SAO's telescopes (Russia), the GHAO's 2.1-m telescope (Cananea, Mexico), and the OAN-SPM's 2.1-m telescope (San-Pedro, Mexico). The observed fluxes of the Halpha, Hbeta, Hgamma and HeII emission lines and of the continuum at the observed wavelength 5117 A, were corrected for the position angle, the seeing and the aperture effects. We found that the continuum and line fluxes varied strongly (up to a factor 6) during the monitoring period. The emission was maximum in 1996-1998, and there were two minima, in 2001 and in 2005. The Halpha, Hgamma and He II fluxes were well correlated with the Hbeta flux. We considered three characteristic periods during which the Hbeta and Halpha profiles were similar: 1996-1999, 2000-2001 and 2002-2006. The line to continuum flux ratios were different; in particular during the first period, the lines were not correlated with the continuum and saturated at high fluxes. In the second and third period, where the continuum flux was small, the Halpha and Hbeta fluxes were well correlated to the continuum flux, meaning that the ionizing continuum was a good extrapolation of the optical continuum. The CCFs are often asymmetrical and the time lags between the lines and the continuum are badly defined indicating the presence of a complex BLR, with dimensions from 1 to 50 light-days.Comment: A&A, accepte

COMPREHENSIVE EPIDEMIOLOGICAL ANALYSIS OF THE TUBERCULOSIS SITUATION AMONG THE DIFFERENT ETHNIC GROUPS OF THE BURYATIA

Comprehensive epidemiological analysis of tuberculosis in the Republic of Buryatia (RB), including among different ethnicgroups (Russian, Buryat, Evenk) presents in the article. Assessment of the epidemiological situationfor 1994-2012 was examined on various parameters (incidence, prevalence and mortality). It was found that the epidemiological situation in RB in the last twenty years were characterized by high incidence of tuberculosis when compared with similar data for Russia as a whole (mean annual incidence 148,1 ± 6,90/0000 и 77.6 ± 2,10/0000 respectively). Among the various ethnic groups living in the RB, the most unfavorable epidemiological indicators identified for the Buryat population. "Safely" group of the population was Evenki. For each of the studied ethnic groups have been identified areas of tuberculosis risk, which had its own characteristics

Возделывание фестулолиума в смеси с люцерной на кормовые цели в лесостепи Западной Сибири

Festulolium is a promising but little-studied fodder crop. The authors found that in the year of laying the herbage of Festulolium in mixtures, the height of plants increased by 6–11% compared with singlespecies sowing. However, the number of shoots per plant decreased from 3 to 2, and the root length decreased by 20%. The survival rate of plants was 84.9–97.4% after winter, depending on the year of sowing. Survival decreased to 46–92% for alfalfa in mixtures, and it was as low as 46–84% when sown with mixture seeds. This was affected by a decrease in reserve nutrients - sugars in the roots of plants. The sugar content decreased by 26%, from 5.14% to 3.77%. No positive effect was observed when sowing with alternating 1–3 rows of festulolium and 1 row of alfalfa. The introduction of nitrogen at a dose of 30 kg a.i. (active ingredient)/ha increased the efficiency of skip-row planting and sowing with a mixture of seeds by 21% due to the positive responsiveness of the components to fertiliser. An increase in the nitrogen dose to 60 kg/ha harmed alfalfa, reducing its share in the herbage to 7% by the third year of use. This decrease was due to the displacement of the more nitrogen-responsive festulolium. The efficiency of crops increases with a reduction in the share of the cereal component and an increase in the percentage of legumes with an alternation of rows of 1:3. The yield was 35.7–42.7 t/ha of green mass, which is higher than that of the single-species sowing of festulolium by 19–53%. The increase is due to an increase in the leaf coverage of alfalfa plants up to 46–49% (against 44% in control) due to the optimisation of layering in the herbage. The introduction of nitrogen at a dose of 30 kg/ha contributes to an increase in yield by 14% (0.43–5.0 t/ ha) due to the increased share of the cereal component in the mixture, an increase in the number of shoots on the plant by 11.1% and their mass by 12.5–17.8%. The introduction of N60 in the joint crops of festulolium and alfalfa is not advisable since it does not give a significant increase in yield and does not pay off the costs incurred.Фестулолиум – перспективная, но малоизученная кормовая культура. Установлено, что в год закладки травостоя у фестулолиума в смесях по сравнению с одновидовым посевом увеличилась на 6–11% высота растений, но уменьшилось с 3 до 2 количество побегов на растении и на 20% длина корня. Выживаемость растений после зимовки в зависимости от года посева составила 84,9–97,4%. У люцерны в смесях выживаемость снизилась до 46–92% и была минимальна при посеве смесью семян – 46–84%. На это повлияло снижение запасных питательных веществ – сахаров в корнях растений, содержание которых уменьшилось на 26% с – 5,14 до 3,77%. При посеве с чередованием 1–3 рядов фестулолиума и 1 ряда люцерны не наблюдалось положительного эффекта. Внесение азота в дозе 30 кг д.в/га повысило эффективность черезрядного посева и посева смесью семян на 21% за счёт положительной отзывчивости компонентов на удобрение. Увеличение дозы азота до 60 кг/га отрицательно подействовало на люцерну, снижая её долю в травостое к третьему году пользования до 7% за счёт вытеснения более отзывчивым на азот фестулолиумом. При уменьшении доли злакового компонента и увеличении доли бобового с чередованием рядов 1 : 3 эффективность посевов возрастает. Урожайность составила 35,7–42,7 т/га зелёной массы, что выше, чем у одновидового посева фестулолиума, на 19–53%. Прибавка обусловлена увеличением облиственности растений люцерны до 46–49% (при 44% в контроле) за счёт оптимизации ярусности в травостое. Внесение азота в дозе 30 кг д.в /га способствует увеличению урожайности на 14% (0,43–5,0 т/ га) за счёт возросшей доли злакового компонента в смеси, увеличения количества побегов на растении на 11,1% и их массы на 12,5–17,8%. Внесение N60 в совместных посевах фестулолиума и люцерны нецелесообразно, поскольку не даёт существенной прибавки урожая и не окупает понесённые затраты