Analysis of Contact Characteristic of Overhead Line and Suspension Clamp

In this paper, a LGJ150/25 type ACSR transmission line and a CGU-3 type suspension clamp are taken as research objects. A contact model of the conductor and the clamp was established by using finite element method. The effects of sag angle of the conductor, holding force and tension force in section are analyzed. The results showed that the contact area in the middle of the clamp is of belt-like type. The extreme values of tress were observed on the edge of the contact area and near the edge of keeper. In clamp section, suspension angle had the greatest influence on contact stress, and then the clamp force. The tension force in section played a most important role in these affecting factors. In the exit section of clamp, the biggest impact factor was tension force in this section, then the suspension angle, the third was clamp force. The results provide theoretical basis on reducing corona loss, optimization the clamp. Doubtlessly, the conclusion has important theoretical significance and application value. DOI: http://dx.doi.org/10.11591/telkomnika.v11i3.222

怪诞化了的抒情诗世界 : 《金瓶梅》的“畸艳”审美特质 = GROTESQUE LYRICAL WORLD: THE QI-YAN AESTHETIC OF THE PLUM IN THE GOLDEN VASE

Ph.DDOCTOR OF PHILOSOPH

A novel stratification framework based on anoikis-related genes for predicting the prognosis in patients with osteosarcoma

BackgroundAnoikis resistance is a prerequisite for the successful development of osteosarcoma (OS) metastases, whether the expression of anoikis-related genes (ARGs) correlates with OS prognosis remains unclear. This study aimed to investigate the feasibility of using ARGs as prognostic tools for the risk stratification of OS.MethodsThe Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases provided transcriptome information relevant to OS. The GeneCards database was used to identify ARGs. Differentially expressed ARGs (DEARGs) were identified by overlapping ARGs with common differentially expressed genes (DEGs) between OS and normal samples from the GSE16088, GSE19276, and GSE99671 datasets. Anoikis-related clusters of patients were obtained by consistent clustering, and gene set variation analysis (GSVA) of the different clusters was completed. Next, a risk model was created using Cox regression analyses. Risk scores and clinical features were assessed for independent prognostic values, and a nomogram model was constructed. Subsequently, a functional enrichment analysis of the high- and low-risk groups was performed. In addition, the immunological characteristics of OS samples were compared between the high- and low-risk groups, and their sensitivity to therapeutic agents was explored.ResultsSeven DEARGs between OS and normal samples were obtained by intersecting 501 ARGs with 68 common DEGs. BNIP3 and CXCL12 were significantly differentially expressed between both clusters (P<0.05) and were identified as prognosis-related genes. The risk model showed that the risk score and tumor metastasis were independent prognostic factors of patients with OS. A nomogram combining risk score and tumor metastasis effectively predicted the prognosis. In addition, patients in the high-risk group had low immune scores and high tumor purity. The levels of immune cell infiltration, expression of human leukocyte antigen (HLA) genes, immune response gene sets, and immune checkpoints were lower in the high-risk group than those in the low-risk group. The low-risk group was sensitive to the immune checkpoint PD-1 inhibitor, and the high-risk group exhibited lower inhibitory concentration values by 50% for 24 drugs, including AG.014699, AMG.706, and AZD6482.ConclusionThe prognostic stratification framework of patients with OS based on ARGs, such as BNIP3 and CXCL12, may lead to more efficient clinical management

Identification, physical mechanisms and impacts of drought–flood abrupt alternation: a review

Climate change has led to an increase in the frequency of extreme events, such as droughts and floods. This study aims to review the literature on the newly proposed phenomenon known as drought-flood abrupt alternation (DFAA). A comprehensive summary is provided to round up the numerous approaches employed to identify DFAA events, as well as its mechanisms and impacts. To provide a reference for responding and managing the emerging intensity and frequency of DFAA events, we conclude the paper by listing the insufficiency of current research and suggesting possible future research directions. As for the impact of DFAA, besides the loss of life and property which can be caused by any natural disaster, a DFAA event severely threatens food security by making a lasting and profound impact on the land productivity through the alteration of the combining conditions of water, soil, and temperature. As for the future research directions, existing indexes developed for DFAA identification should be improved by downscaling the temporal and spatial scale, with interactions of neighboring drought and flood events taken into consideration. What’s more, to better protect human society from the losses caused by DFAA, researches on accurate DFAA prediction are encouraged

Physiological effects of combined NaCl and NaHCO3 stress on the seedlings of two maple species

Salt stress impacts growth and physiological processes in plants, and some plants exposed to salt stress will produce physiological mechanisms to adapt to the new environment. However, the effects of combined NaCl and NaHCO3 stress on the seedlings of Acer species are understudied. In this study, we designed an experiment to measure physiological characteristics by establishing a range of NaCl and NaHCO3 concentrations (0, 25, 50, 75, and 100 mmol L-1) to estimate the compound salt tolerance of Acer ginnala and Acer palmatum. When the concentrations of NaCl and NaHCO3 were 25 mmol L-1, the leaf water content, relative conductivity, malondialdehyde (MDA) content, proline content, soluble sugar content, and chlorophyll did not change (p > 0.05) in two maple seedlings. At concentrations greater than 50 mmol L-1, the relative conductivity and MDA content increased, proline and soluble sugars accumulated, and the potential activity of PS II (Fv/Fo), potential photochemical efficiency of PS II (Fv/Fm), PS II actual photochemical efficiency (Yield), and photosynthetic electron transfer efficiency (ETR) decreased (p < 0.05). The superoxide dismutase (SOD) and catalase (CAT) activities showed the same trend of first increasing and then decreasing (p < 0.05). The peroxidase (POD) activity increased only when concentrations of NaCl and NaHCO3 were 100 mmol L-1, while there was no statistical difference between the other treatments and the control. Therefore, the two maple seedlings adjusted their osmotic balance and alleviated oxidative stress by accumulating proline, soluble sugars and increasing CAT and SOD activities. Further analysis showed that both species are salt tolerant and the salt tolerance of Acer ginnala is better than that of Acer palmatum

Construction of Flexible Piezoceramic Array with Ultrahigh Piezoelectricity via a Hierarchical Design Strategy

The µW-level power density of flexible piezoelectric energy harvesters (FPEHs) restricts their potential in applications related to high-power multifunctional wearable devices. To overcome this challenge, a hierarchical design strategy is proposed by forming porous piezoceramics with an optimum microstructure into an ordered macroscopic array structure to enable the construction of high performance FPEHs. The porous piezoceramic elements allows optimization of the sensing and harvesting Figure of merit, and the array structure causes a high level of effective strain under a mechanical load. The introduction of a network of polymer channels between the piezoceramic array also provides increased device flexibility, thereby allowing the device to attach and conform to the curved contours of the human body. The unique hierarchical piezoceramic array architecture exhibits superior flexibility, a high open circuit voltage (618 V), high short circuit current (188 µA), and ultrahigh power density (19.1 mW cm−2). This energy density value surpasses previously reported high-performance FPEHs. The ultrahigh power flexible harvesting can charge a 0.1 F supercapacitor at 2.5 Hz to power high-power electronic devices. Finally, the FPEH is employed in two novel applications related to fracture healing monitoring and self-powered wireless position tracking in extreme environments.</p

Construction of Flexible Piezoceramic Array with Ultrahigh Piezoelectricity via a Hierarchical Design Strategy

The µW-level power density of flexible piezoelectric energy harvesters (FPEHs) restricts their potential in applications related to high-power multifunctional wearable devices. To overcome this challenge, a hierarchical design strategy is proposed by forming porous piezoceramics with an optimum microstructure into an ordered macroscopic array structure to enable the construction of high performance FPEHs. The porous piezoceramic elements allows optimization of the sensing and harvesting Figure of merit, and the array structure causes a high level of effective strain under a mechanical load. The introduction of a network of polymer channels between the piezoceramic array also provides increased device flexibility, thereby allowing the device to attach and conform to the curved contours of the human body. The unique hierarchical piezoceramic array architecture exhibits superior flexibility, a high open circuit voltage (618 V), high short circuit current (188 µA), and ultrahigh power density (19.1 mW cm−2). This energy density value surpasses previously reported high-performance FPEHs. The ultrahigh power flexible harvesting can charge a 0.1 F supercapacitor at 2.5 Hz to power high-power electronic devices. Finally, the FPEH is employed in two novel applications related to fracture healing monitoring and self-powered wireless position tracking in extreme environments.</p