Toxic Megacolon and Perforated Fungal Diverticulitis due to Mucor indicus Infection in a Patient with Chronic Myelogenous Leukemia

Introduction: Intestinal zygomycosis is a rare infection by the fungi zygomycetes that have little intrinsic pathogenicity in normal hosts and mainly affects immune compromised patients. Mucor indicus is a rare, emerging cause of intestinal zygomycosis with only 8 reported cases in English literature since 1986.Presentation of Case: We reported an unusual case of toxic megacolon, fungal diverticulitis with perforation and liver abscesses caused by Mucor indicus in a patient with chronic myelogenous leukemia (CML), B-lymphoid blast crisis and pancytopenia. The patient was treated with total colectomy and aggressive systemic anti-fungal regimens consisting of amphotericin, caspofungin and posaconazole. However, his fungal abscess in the liver persisted after colectomy, which was confirmed by liver biopsy at four months after total colectomy. His CML and B-lymphoid blast crisis was successfully treated with hyper-CVAD plus dasatinib and had been in complete remission. The patient was alive and continued to have stable fungal infection in the liver based on CT scan at 32 months after total colectomy, for which he has been on posaconazole monotherapy.Conclusions: Mucor indicus may cause a rare invasive zygomycosis that tends to involve gastrointestinal tract and to disseminate to the liver

Numerical simulation for machining S-tube by abrasive flow with various particle volume fractions

Abrasive flow machining has become an economical and efficient ultra-precision process for machining complex-shaped pipe parts, and processing effect is exceedingly subject to particle volume fraction. In this paper, aiming at uncovering the influence of various particle volume fractions on the machining result of abrasive flow finishing, based on fluid mechanics theory, mixed phase model and discrete phase model were conducted, FLUENT software was resorted to simulate the numerical characteristics of the solid-liquid two-phase flow field in the inner channel of S-tube with different-particle-volume-fraction abrasive flows, the mechanism of erosion and wear of particles was uncovered, which provides a theoretical basis for abrasive flow machining S-tube structured components

(2-Acetyl­phenolato)(2,2′-bipyridine)nitratocopper(II)

In the title compound, [Cu(C8H7O2)(NO3)(C10H8N2)], the CuII ion is five-coordinate in a distorted square-pyramidal geometry. The basal positions are occupied by two N atoms from a 2,2′-bipyridine ligand and two O atoms from the 2-acetyl­phenolate anion. The axial position is occupied by one O atom of a nitrate anion. In the bipyridine ligand, the two pyridine rings are slightly twisted by an angle of 3.5 (1)°. The crystal structure is stabilized by C—H⋯O hydrogen bond

Complete two-loop electroweak corrections to e+e−→HZe^+e^-\rightarrow HZ

We compute the complete two-loop electroweak corrections to the Higgsstralung process $e^+e^-\rightarrow HZ$ at the future Higgs factory. The Feynman integrals involved in the computation are decomposed into linear combinations of a minimal set of master integrals taking advantage of the recent developments of integral reduction techniques. The master integrals are then evaluated by differential equations with boundary conditions provided by the auxiliary mass flow method. Our final result for given $\sqrt{s}$ is expressed as a piecewise function defined by several deeply expanded power series, which has high precision and can be further manipulated efficiently. Our calculation presents the first complete two-loop electroweak corrections for processes with four external particles.Comment: 5 pages, 2 figures. arXiv admin note: text overlap with arXiv:2209.1425