Power Generation with Renewable Energy and Advanced Supercritical CO2 Thermodynamic Power Cycles: A Review

Supercritical CO2 (S-CO2) thermodynamic power cycles have been considerably investigated in the applications of fossil fuel and nuclear power generation systems, considering their superior characteristics such as compactness, sustainability, cost-effectiveness, environmentally friendly working fluid, and high thermal efficiency. They can be potentially integrated and applied with various renewable energy systems for low-carbon power generation such that extensive studies in these areas have also been conducted substantially. However, there is a shortage of reviews that specifically concentrate on the integrations of S-CO2 with renewable energy encompassing biomass, solar, geothermal, and waste heat. It is thus necessary to provide an update and overview of the development of S-CO2 renewable energy systems and identify technology and integration opportunities for different types of renewable resources. Correspondingly, this paper not only summarizes the advantages of CO2 working fluid, design layouts of S-CO2 cycles, and classifications of renewable energies to be integrated but also reviews the recent research activities and studies carried out worldwide on advanced S-CO2 power cycles with renewable energy. Moreover, the performance and development of various systems are well grouped and discussed

CFD Modelling of Finned-tube CO2 Gas Cooler for Refrigeration Systems

As a main component in a refrigeration system, finned-tube CO2 gas cooler plays an important role to the system performance and thus needs to be thoroughly investigated. To achieve this, some effective parameters including the CO2 and air fluid velocity fields, temperature profiles and heat transfer characteristics at different operating conditions are predicted and analysed by means of Computational Fluid Dynamics (CFD) modelling and simulation. It is noted that CFD modelling can accurately obtain the local heat transfer coefficients of both air and refrigerant sides, which are difficult to be predicted by conventional empirical correlations. This paper investigates the effect of varied operational parameters on local heat transfer coefficients and temperature profiles of the working fluids in a finned-tube CO2 gas cooler by means of CFD modelling. As one of the simulation results, it is found that the approach temperature decreases with increased air inlet velocity. The model has been compared and validated with experimental measurements and literature correlations. The research methods and outcomes can be used for further investigation and optimization in this area

Noninvasive Two-Dimensional Strain Imaging of Atherosclerosis: A Preliminary Study in Carotid Arteries In Vivo

AbstractAtherosclerosis remains a major cause of mortality all over the world and the sudden rupture of atherosclerotic plaque is the most important assassin. Vascular ultrasound elastography has shown promise in estimating the elastic properties to evaluate the plaque vulnerability. Contrary to intravascular elastography, noninvasive applications use a transcutaneous ultrasound transducer that is inexpensive, re-useable and convenient. To estimate the strain map, we employ a cross-correlation method in complex field to extract both the magnitude and phase messages of the ultrasound RF-echo signal. Two-dimension noninvasive carotid elastography was studied in atherosclerotic rats and New Zealand Rabbits and also in healthy volunteer, and the results indicate huge potential for diagnosis of the vulnerability of atheromatous plaques

Modeling on Stress Evolution of Step Part for Casting-heat Treatment Processes

AbstractHeat treatment usually follows the casting process to improve the physical properties of parts. Under the strong assumption that casting has no effect on the following heat treatment, the modeling of heat treatment process is currently based on ideal material conditions with zero residual stress and uniform properties. In this paper, residual stress generated by casting has been introduced as the initial conditions for a heat treated step part of 4140 steel. The results have been compared with that of no consideration about initial residual stresses of casting

BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway

SummaryObjectiveBone morphogenic protein (BMP)-2 is approved for fracture non-union and spine fusion. We aimed to further dissect its downstream signaling events in chondrocytes with the ultimate goal to develop novel therapeutics that can mimic BMP-2 effect but have less complications.MethodsBMP-2 effect on cyclooxygenase (COX)-2 expression was examined using Real time quantitative PCR (RT-PCR) and Western blot analysis. Genetic approach was used to identify the signaling pathway mediating the BMP-2 effect. Similarly, the pathway transducing the PGE2 effect on ATF4 was investigated. Immunoprecipitation (IP) was performed to assess the complex formation after PGE2 binding.ResultsBMP-2 increased COX-2 expression in primary mouse costosternal chondrocytes (PMCSC). The results from the C9 Tet-off system demonstrated that endogenous BMP-2 also upregulated COX-2 expression. Genetic approaches using PMCSC from ALK2fx/fx, ALK3fx/fx, ALK6−/−, and Smad1fx/fx mice established that BMP-2 regulated COX-2 through activation of ALK3–Smad1 signaling. PGE-2 EIA showed that BMP-2 increased PGE2 production in PMCSC. ATF4 is a transcription factor that regulates bone formation. While PGE2 did not have significant effect on ATF4 expression, it induced ATF4 phosphorylation. In addition to stimulating COX-2 expression, BMP-2 also induced phosphorylation of ATF4. Using COX-2 deficient chondrocytes, we demonstrated that the BMP-2 effect on ATF4 was COX-2-dependent. Tibial fracture samples from COX-2−/− mice showed reduced phospho-ATF4 immunoreactivity compared to wild type (WT) ones. PGE2 mediated ATF4 phosphorylation involved signaling primarily through the EP2 and EP4 receptors and PGE2 induced an EP4-ERK1/2-RSK2 complex formation.ConclusionsBMP-2 regulates COX-2 expression through ALK3–Smad1 signaling, and PGE2 induces ATF4 phosphorylation via EP4-ERK1/2-RSK2 axis

Running coupling: Does the coupling between dark energy and dark matter change sign during the cosmological evolution?

In this paper we put forward a running coupling scenario for describing the interaction between dark energy and dark matter. The dark sector interaction in our scenario is free of the assumption that the interaction term $Q$ is proportional to the Hubble expansion rate and the energy densities of dark sectors. We only use a time-variable coupling $b(a)$ (with $a$ the scale factor of the universe) to characterize the interaction $Q$. We propose a parametrization form for the running coupling $b(a)=b_0a+b_e(1-a)$ in which the early-time coupling is given by a constant $b_e$, while today the coupling is given by another constant, $b_0$. For investigating the feature of the running coupling, we employ three dark energy models, namely, the cosmological constant model ($w=-1$), the constant $w$ model ($w=w_0$), and the time-dependent $w$ model ($w(a)=w_0+w_1(1-a)$). We constrain the models with the current observational data, including the type Ia supernova, the baryon acoustic oscillation, the cosmic microwave background, the Hubble expansion rate, and the X-ray gas mass fraction data. The fitting results indicate that a time-varying vacuum scenario is favored, in which the coupling $b(z)$ crosses the noninteracting line ($b=0$) during the cosmological evolution and the sign changes from negative to positive. The crossing of the noninteracting line happens at around $z=0.2-0.3$, and the crossing behavior is favored at about 1$\sigma$ confidence level. Our work implies that we should pay more attention to the time-varying vacuum model and seriously consider the phenomenological construction of a sign-changeable or oscillatory interaction between dark sectors.Comment: 8 pages, 5 figures; refs added; to appear in EPJ