Characteristics of transient pressure performance of horizontal wells in fractured-vuggy tight fractal reservoirs considering nonlinear seepage

International audienceSince the classical seepage theory has limitations in characterizing the heterogeneity of fractured-vuggy tight reservoirs, well test interpretation results are not consistent with actual production by far. Based on the nonlinear percolation theory, a new nonlinear seepage equation considering the boundary layer and yield stress was derived to describe the seepage characteristics of dense matrix blocks and the stress sensitivity and fractal features of fracture systems were characterized by applying the fractal theory. Thus, the nonlinear model of a horizontal well in a fractured-vuggy tight fractal reservoir was established naturally. Then the finite element method was applied to solve the bottom hole pressure based on the processing of internal boundary conditions. After solving the model, the seepage characteristics of different models were summarized by analyzing the bottom hole pressure dynamic curves and the sensitivity analysis of multiple parameters such the nonlinear parameter and fractal index were conducted. Finally, the practicality of the model was proved through a field application. The results show that the pressure dynamic curves can be divided into nine flow stages and the increase of the nonlinear parameter will cause the intensity of the cross flow from matrix blocks to the fracture system to decrease. The fractal index is irrelevant to the intensity of the cross flow while it decides the upwarping degree of the curve at the middle and late flow stages. On the basis of the results of the field application, it can be concluded that the model fits well with actual production and the application of this model can improve the accuracy of well test interpretation

Historical Trends in Air Temperature, Precipitation, and Runoff of a Plateau Inland River Watershed in North China

Understanding historical trends in temperature, precipitation, and runoff is important but incomplete for developing adaptive measures to climate change to sustain fragile ecosystems in cold and arid regions, including the Balagaer River watershed on the Mongolian Plateau of northeast China. The objective of this study was to detect such trends in this watershed from 1959 to 2017. The detection was accomplished using a Mann-Kendall sudden change approach at annual and seasonal time scales. The results indicated that the abrupt changes in temperature preceded that in either runoff or precipitation; these abrupt changes occurred between 1970 and 2004. Significant (α = 0.05) warming trends were found at the minimum temperatures in spring (0.041 °C a−1), summer (0.037 °C a−1), fall (0.027 °C a−1), and winter (0.031 °C a−1). In contrast, significant decreasing trends were found in the precipitation (−1.27 mm a−1) and runoff (−0.069 mm a−1) in the summer. Marginally increasing trends were found in the precipitation in spring (0.18 mm a−1) and fall (0.032 mm a−1), whereas an insignificant decreasing trend was found in the runoffs in these two seasons. Both precipitation and runoff in the wet season exhibited a significant decreasing trend, whereas in the dry season, they exhibited a marginally increasing trend. Sudden changes in spring runoff and sudden rises in temperature are the main causes of sudden changes in basin rainfall

The workflow to analyze hydraulic fracture effect on hydraulic fractured horizontal well production in composite formation system

Hydraulic fracturing generally leads to highly complex hydraulic networks for tight oil reservoirs. It is significant to understand the hydraulic fracture effect on well performance. As an effective tool, semi-analytical solution for well pressure transient analysis (PTA) and rate transient analysis (RTA) is used in large amount because of higher calculation efficiency than numerical solution. In this paper, the PTA and RTA methods and result of composite formation system (CFS) are shown comprehensively. Firstly, a mathematical model of multistage fractured horizontal well (MsFHW) in CFS was proposed for tight oil reservoir with different regions and formation properties. In the model, two regions with different formation parameters were distinguished. This assumption of two regions, i.e. CFS is a composite tight reservoir formed after hydraulic fracturing. Difference of finite hydraulic fracture conductivity, inclined angle of hydraulic fracture, different shapes of multi-wing fractures in perforating point are considered to make this model powerful to analyze production performance of different MsFHW types. The inner and outer regions were assumed as dual porosity medium but single porosity medium model can also be solved by simplification. Then, the solution of MsFHW performance analysis model is obtained by source function method and the source function superposition principle which are common used in PTA and RTA. PTA for well producing at a constant production rate and RTA for well producing at a constant wellbore pressure were obtained and discussed. Different flow regimes were divided for different fracture geometry situations. The effects of different MsFHW types on PTA and RTA were analyzed. The inflow performance for different hydraulic fractures were presented.Cited as: Yuan, J., Jiang, R., Zhang, W. The workflow to analyze hydraulic fracture effect on hydraulic fractured horizontal well production in composite formation system. Advances in Geo-Energy Research, 2018, 2(3): 319-342, doi: 10.26804/ager.2018.03.0

The workflow to analyze hydraulic fracture effect on hydraulic fractured horizontal well production in composite formation system

Hydraulic fracturing generally leads to highly complex hydraulic networks for tight oil reservoirs. It is significant to understand the hydraulic fracture effect on well performance. As an effective tool, semi-analytical solution for well pressure transient analysis (PTA) and rate transient analysis (RTA) is used in large amount because of higher calculation efficiency than numerical solution. In this paper, the PTA and RTA methods and result of composite formation system (CFS) are shown comprehensively. Firstly, a mathematical model of multistage fractured horizontal well (MsFHW) in CFS was proposed for tight oil reservoir with different regions and formation properties. In the model, two regions with different formation parameters were distinguished. This assumption of two regions, i.e. CFS is a composite tight reservoir formed after hydraulic fracturing. Difference of finite hydraulic fracture conductivity, inclined angle of hydraulic fracture, different shapes of multi-wing fractures in perforating point are considered to make this model powerful to analyze production performance of different MsFHW types. The inner and outer regions were assumed as dual porosity medium but single porosity medium model can also be solved by simplification. Then, the solution of MsFHW performance analysis model is obtained by source function method and the source function superposition principle which are common used in PTA and RTA. PTA for well producing at a constant production rate and RTA for well producing at a constant wellbore pressure were obtained and discussed. Different flow regimes were divided for different fracture geometry situations. The effects of different MsFHW types on PTA and RTA were analyzed. The inflow performance for different hydraulic fractures were presented.Cited as: Yuan, J., Jiang, R., Zhang, W. The workflow to analyze hydraulic fracture effect on hydraulic fractured horizontal well production in composite formation system. Advances in Geo-Energy Research, 2018, 2(3): 319-342, doi: 10.26804/ager.2018.03.0

Reconstructing Graph Diffusion History from a Single Snapshot

Diffusion on graphs is ubiquitous with numerous high-impact applications. In these applications, complete diffusion histories play an essential role in terms of identifying dynamical patterns, reflecting on precaution actions, and forecasting intervention effects. Despite their importance, complete diffusion histories are rarely available and are highly challenging to reconstruct due to ill-posedness, explosive search space, and scarcity of training data. To date, few methods exist for diffusion history reconstruction. They are exclusively based on the maximum likelihood estimation (MLE) formulation and require to know true diffusion parameters. In this paper, we study an even harder problem, namely reconstructing Diffusion history from A single SnapsHot} (DASH), where we seek to reconstruct the history from only the final snapshot without knowing true diffusion parameters. We start with theoretical analyses that reveal a fundamental limitation of the MLE formulation. We prove: (a) estimation error of diffusion parameters is unavoidable due to NP-hardness of diffusion parameter estimation, and (b) the MLE formulation is sensitive to estimation error of diffusion parameters. To overcome the inherent limitation of the MLE formulation, we propose a novel barycenter formulation: finding the barycenter of the posterior distribution of histories, which is provably stable against the estimation error of diffusion parameters. We further develop an effective solver named DIffusion hiTting Times with Optimal proposal (DITTO) by reducing the problem to estimating posterior expected hitting times via the Metropolis--Hastings Markov chain Monte Carlo method (M--H MCMC) and employing an unsupervised graph neural network to learn an optimal proposal to accelerate the convergence of M--H MCMC. We conduct extensive experiments to demonstrate the efficacy of the proposed method.Comment: Full version of the KDD 2023 paper. Our code is available at https://github.com/q-rz/KDD23-DITT

Near-Infrared Photoluminescence and Electrochemiluminescence from an Exceptionally Simple Boron Difluoride Formazanate Dye

Electrochemiluminescence involves the generation of light via electrochemical reactions and has recently shown utility for single-cell imaging. To further develop this novel imaging platform, it is necessary to produce readily available dyes that photoluminesce and electrochemiluminesce in the near-infrared region to limit absorption by biological tissue. To address this need, we prepared a boron difluoride formazanate dye that exhibits near-infrared photoluminescence and electrochemiluminescence in two straightforward synthetic steps. Examination of its solid-state structure suggests that the N-aryl substituents have significant quinoidal character, which narrows the S1-S0 energy gap and leads to near-infrared absorption and photoluminescence. Electrochemical properties were probed using cyclic voltammetry and revealed four electrochemically reversible waves. Electrochemiluminescence properties were examined in the presence of tri-n-propylamine, leading to maximum intensity at 910 nm, at least 85 nm (1132 cm‒1) red-shifted compared to all other organic dyes. This work sets the stage for the development of future generations of dyes for emerging applications, including single-cell imaging, that require near-infrared photoluminescence and electrochemiluminescence

Symbol-level Integrated Sensing and Communication enabled Multiple Base Stations Cooperative Sensing

With the support of integrated sensing and communication (ISAC) technology, mobile communication system will integrate the function of wireless sensing, thereby facilitating new intelligent applications such as smart city and intelligent transportation. Due to the limited sensing accuracy and sensing range of single base station (BS), multi-BS cooperative sensing can be applied to realize high-accurate, long-range and continuous sensing, exploiting the specific advantages of large-scale networked mobile communication system. This paper proposes a cooperative sensing method suitable to mobile communication systems, which applies symbol-level sensing information fusion to estimate the location and velocity of target. With the demodulation symbols obtained from the echo signals of multiple BSs, the phase features contained in the demodulation symbols are used in the fusion procedure, which realizes cooperative sensing with the synchronization level of mobile communication system. Compared with the signal-level fusion in the area of distributed aperture coherence-synthetic radars, the requirement of synchronization is much lower. When signal-to-noise ratio (SNR) is -5 dB, it is evaluated that symbol-level multi-BS cooperative sensing effectively improves the accuracy of distance and velocity estimation of target. Compared with single-BS sensing, the accuracy of distance and velocity estimation is improved by 40% and 72%, respectively. Compared with data-level multi-BS cooperative sensing based on maximum likelihood (ML) estimation, the accuracy of location and velocity estimation is improved by 12% and 63%, respectively. This work may provide a guideline for the design of multi-BS cooperative sensing system to exploit the widely deployed networked mobile communication system.Comment: 15 pages, 17 figures, 2 table

Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation

Development of anticancer drugs is challenging. Indeed, much research effort has been spent in the development of new drugs to improve clinical outcomes with minimal toxicity. We have previously reported that a formulation of lipid gold porphyrin nanoparticles reduced systemic drug toxicity when compared with free gold porphyrin. In this study, we investigated the delivery and treatment efficiency of PEG surface-modified lipid nanoparticles as a carrier platform. We encapsulated antitumor drugs into PEG-modified lipid nanoparticles and these were characterized by size, zeta potential, and encapsulation efficiency. The delivery efficiency into tumor tissue was evaluated using a biodistribution study. To evaluate antitumor efficacy, gold porphyrin or camptothecin (a DNA topoisomerase I inhibitor) were encapsulated and compared using an in vivo neuroblastoma (N2A) model. We showed that drug encapsulation into PEG-modified lipid nanoparticles enhanced the preferential uptake in tumor tissue. Furthermore, higher tumor killing efficiency was observed in response to treatment with PEG-modified lipid nanoparticles encapsulating gold porphyrin or camptothecin when compared with free gold porphyrin or free camptothecin. The in vivo antitumor effect was further confirmed by study of tumor inhibition and positive apoptosis activity. Surface modification of lipophilic nanoparticles with PEG increased the efficiency of drug delivery into tumor tissue and subsequently more effective antitumor activity. This specific design of a chemotherapeutic agent using nanotechnology is important in the development of a safe and effective drug in cancer therapy.published_or_final_versio

Aluminum Complexes of N2O23‒ Formazanate Ligands Supported by Phosphine Oxide Donors

The synthesis and characterization of a new family of phosphine-oxide-supported aluminum formazanate complexes (7a, 7b, 8a, 9a) are reported. X-ray diffraction studies revealed that the aluminum atoms in the complexes adopt an octahedral geometry in the solid state. The equatorial positions are occupied by an N2O23‒ formazanate ligand, and the axial positions are occupied by L-type phosphine oxide donors. UV-vis absorption spectroscopy revealed that the complexes were strongly absorbing (ε ~ 30,000 M‒1 cm‒1) between 500 and 700 nm. The absorption maxima in this region were simulated using time-dependent density-functional theory. With the exception of 3-cyano substituted complex 7b, which showed maximum luminescence intensity in the presence of excess phosphine oxide, the title complexes are non-emissive in solution and the solid state. The electrochemical properties of the complexes were probed using cyclic voltammetry. Each complex underwent sequential one-electron oxidations in potential ranges of ‒0.12 to 0.29 V and 0.62 to 0.97 V, relative to the ferrocene/ferrocenium redox couple. Electrochemical reduction events were observed at potentials between ‒1.34 and ‒1.75 V. When combined with tri-n-propylamine as a coreactant, complex 7b acted as an electrochemiluminescence emitter with a maximum electrochemiluminescence intensity at a wavelength of 735 nm, red-shifted relative to the photoluminescence maximum of the same compound

Benzosiloles with Crystallization-induced Emission Enhancement of Electrochemiluminescence: Synthesis, Electrochemistry, and Crystallography

Crystallization-induced emission enhancement (CIEE) was demonstrated for the first time for electrochemilunimescence (ECL) with two new benzosiloles. Compared with their solution, the films of the two benzosiloles gave CIEE of 24 times and 16 times. The mechanism of the CIEE-ECL was examined by spooling ECL spectroscopy, X-ray crystal structure analysis, photoluminescence, and DFT calculation. This CIEE-ECL system is a complement to the well-established aggregation-induced emission enhancement (AIEE) systems. Unique intermolecular interactions are noted in the crystalline chromophore. The first heterogeneous ECL system is established for organic compounds with highly hydrophobic properties