304 research outputs found

    Study of Evolution Model of China Education and Research Network

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    By searching the hyperlinks with domain name “.edu.cn” which constitutes the China Education and Research Network, we build a complex directed network containing 366,422 web pages containing 540,755 URLs. These URLs constitute a complex directed network through self-organization. By analyzing the topology of China Education and Research Network, we found that it is different from the common Internet in several aspects. Most of the vertices have incoming links, a few vertices have outgoing links, and very few vertices have both incoming and outgoing links. The vertex distribution has a power-law tail. A large proportion of newly added edges always connect with those pages selected from one subnetwork that they belong to, instead of connecting with the pages selected from the whole network. According to these features, we presented the evolution model of this complex directed network. The results indicate that this model reflects some main characteristics of China Education and Research Network

    Development of a New Dual-Cylinder Rotary Compressor for VI System

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    On the vapor compression refrigeration system, Vapor injection (VI, the phase separator type injection or the internal heat exchanger type injection) compression cycle’s superiority over non-injection cycle has been well known. VI system produces the high heating/cooling capacity, and its power consumption is less than the non-injection system. But if a VI compression cycle uses a single rotary compressor, there is the problem that refrigerant injection increases the indicated power by mixture loss. If we use a two-stage rotary compressor, indicated power also increases because of its two times exhaust process. To solve these problems, we developed a new dual-cylinder rotary compressor for VI systems, one of the cylinders is used to compress the gas from the evaporator, and the other is used to compress the gas from the phase separator (flash-tank). Its design method is discussed and its performance under different conditions is analyzed

    Improved Biclique Cryptanalysis of the Lightweight Block Cipher Piccolo

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    Biclique cryptanalysis is a typical attack through finding a biclique which is a type of bipartite diagram to reduce the computational complexity. By investigating the subkey distribution and the encryption structure, we find out a weakness in the key schedule of Piccolo-80. A 6-round biclique is constructed for Piccolo-80 and a 7-round biclique for Piccolo-128. Then a full round biclique cryptanalysis of Piccolo is presented. The results of the attacks are with data complexity of 240 and 224 chosen ciphertexts and with computational complexity of 279.22 and 2127.14, respectively. They are superior to other known results of biclique cryptanalytic on Piccolo

    Atomistic simulations of thermodynamic properties of liquid gallium from first principles

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    In the research of condensed matter, atomistic dynamic simulations play a crucial role, particularly in revealing dynamic processes, phase transitions and thermodynamic statistics macroscopic physical properties in systems such as solids and liquids. For a long time, simulating complex and disordered liquids has been a challenge compared to ordered crystalline structures. The primary reasons for this challenge are the lack of precise force field functions and the neglect of nuclear quantum effects. To overcome these two limits in simulation of liquids, we use a deep potential (DP) with quantum thermal bath (QTB) approach. DP is a machine learning model are sampled from density functional theory and able to do large-scale atomic simulations with its precision. QTB is a method which incorporates nuclear quantum effects by quantum fluctuation dissipation. The application of this first principles approach enable us to successfully describe the phase transition processes in solid and liquid Gallium (Ga) as well as the associated dynamic phenomena. More importantly, we obtain the thermodynamic properties of liquid Ga, such as internal energy, specific heat, enthalpy change, entropy and Gibbs free energy, and these results align remarkably well with experiments. Our research has opened up a new paradigm for the study of dynamics and thermodynamics in liquids, amorphous materials, and other disordered systems, providing valuable insights and references for future investigations.Comment: 7 pages, 11 figures for maintext; 6pages, 8 figures for supplementary material

    Simultaneous measurement of displacement and temperature based on two cascaded balloon-like bent fibre structures

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    A low-cost optical fibre sensor based on two cascaded balloon-like bent fibre (BBF) structures for simultaneous displacement and temperature measurement is reported. The sensor is fabricated by cascading two balloon-like bent single-mode fibres (SMFs) which with different bending radii, generating two separate interference dips within a limited wavelength range. The wavelength of the two interference dips exhibits different responses to external displacement and temperature variations, hence simultaneous measurement of displacement and temperature is realized. Experimental results show that the proposed optical fibre sensor achieves a displacement sensitivity of −318.8 pm/μm and a temperature sensitivity of 47.4 pm/°C. Taking advantage of its low-cost, ease of fabrication, and experimentally determined high sensitivity, the sensor in this investigation can be potentially applied in both displacement and temperature measurement fields

    Knockdown of ATF3 suppresses the progression of ischemic stroke through inhibiting ferroptosis

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    ObjectiveCurrent therapies towards ischemic stroke (IS) are still not satisfied, and alternative strategies targeting ferroptosis may be another choice. The purpose of this study is to screen potential ferroptosis-related genes involving in IS.MethodsA rat model of IS was established via middle cerebral artery occlusion. Differentially expressed genes (DEGs) were screened from the model rats through transcriptional sequencing. Among the isolated DEGs, the expression of several attractive DEGs relating with ischemic injury was confirmed by qRT-PCR. Then, ATF3 relating with both IS and ferroptosis was selected a candidate gene for functional assays. After knockdown of ATF3 in the model rats, the infarction, histopathology, apoptosis, and ferroptosis in brain tissues were evaluated.ResultsIS model was successfully established in rats, exhibiting the emergence of infarction area, histopathological injury, and enhanced cell apoptosis. Total 699 up-regulated DEGs and 461 down-regulated DEGs were screened from the model rats. qRT-PCR verified the up-regulation of Hspa1b, Tfpi2, Ptx3, and Atf3, and the down-regulation of Smyd1 and Tacr2 in the Model group compared with those in the Sham group. It is noteworthy that knockdown of ATF3 decreased the infarction area, relieved histopathological injury, weakened apoptosis, and inhibited ferroptosis in the model rats.ConclusionSeveral candidate genes in relation with IS were revealed. More importantly, knockdown of ATF3 may relieve IS through inhibiting ferroptosis
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