Flaxseed Bioactive Compounds: Chemical Composition, Functional Properties, Food Applications and Health Benefits-Related Gut Microbes

Flaxseed (Linum usitatissimum L.) has gained worldwide recognition as a health food because of its abundance in diverse nutrients and bioactive compounds such as oil, fatty acids, proteins, peptides, fiber, lignans, carbohydrates, mucilage, and micronutrients. These constituents attribute a multitude of beneficial properties to flaxseed that makes its use possible in various applications, such as nutraceuticals, food products, cosmetics, and biomaterials. The importance of these flaxseed components has also increased in modern times because of the newer trend among consumers of greater reliance on a plant-based diet for fulfilling their nutritional requirements, which is perceived to be hypoallergenic, more environmentally friendly, sustainable, and humane. The role of flaxseed substances in the maintenance of a healthy composition of the gut microbiome, prevention, and management of multiple diseases has recently been elucidated in various studies, which have highlighted its importance further as a powerful nutritional remedy. Many articles previously reported the nutritive and health benefits of flaxseed, but no review paper has been published reporting the use of individual flaxseed components in a manner to improve the techno-functional properties of foods. This review summarizes almost all possible applications of flaxseed ingredients in food products from an extensive online literature survey; moreover, it also outlines the way forward to make this utilization even better

SpeechMirror: A Multimodal Visual Analytics System for Personalized Reflection of Online Public Speaking Effectiveness

As communications are increasingly taking place virtually, the ability to present well online is becoming an indispensable skill. Online speakers are facing unique challenges in engaging with remote audiences. However, there has been a lack of evidence-based analytical systems for people to comprehensively evaluate online speeches and further discover possibilities for improvement. This paper introduces SpeechMirror, a visual analytics system facilitating reflection on a speech based on insights from a collection of online speeches. The system estimates the impact of different speech techniques on effectiveness and applies them to a speech to give users awareness of the performance of speech techniques. A similarity recommendation approach based on speech factors or script content supports guided exploration to expand knowledge of presentation evidence and accelerate the discovery of speech delivery possibilities. SpeechMirror provides intuitive visualizations and interactions for users to understand speech factors. Among them, SpeechTwin, a novel multimodal visual summary of speech, supports rapid understanding of critical speech factors and comparison of different speech samples, and SpeechPlayer augments the speech video by integrating visualization of the speaker's body language with interaction, for focused analysis. The system utilizes visualizations suited to the distinct nature of different speech factors for user comprehension. The proposed system and visualization techniques were evaluated with domain experts and amateurs, demonstrating usability for users with low visualization literacy and its efficacy in assisting users to develop insights for potential improvement.Comment: Main paper (11 pages, 6 figures) and Supplemental document (11 pages, 11 figures). Accepted by VIS 202

Diameter effect on the heat transfer of supercritical hydrocarbon fuel in horizontal tubes under turbulent conditions

This document is the Accepted Manuscript version of the following article: Zeyuan Cheng, Zhi Tao, Jianqin Zhu, and Hongwei Wu, ‘Diameter effect on the heat transfer of supercritical hydrocarbon fuel in horizontal tubes under turbulent conditions’, Applied Thermal Engineering, Vol. 134: 39-53, April 2018. Under embargo until 31 January 2019. The final, definitive version is available online at: https://doi.org/10.1016/j.applthermaleng.2018.01.105This article presented a numerical investigation of supercritical heat transfer of the hydrocarbon fuel in a series of horizontal tubes with different diameters. The Reynolds averaging equations of mass, momentum and energy with the LS low-Reynolds number turbulence model have been solved using the pressure-based segregated solver based on the finite volume method. For the purpose of comparison, a four-species surrogate model and a ten-species surrogate model of the aviation kerosene RP-3 (Rocket Propellant 3) were tested against the published experimental data. In the current study, the tube diameter varied from 2 mm to 10 mm and the pressure was 3 MPa with heat flux to mass flux ratios ranging from 0.25 to 0.71 kJ/kg. It was found that the buoyancy has significant effect on the wall temperature non-uniformity in the horizontal tube. With the increase of the diameter, the buoyancy effect enhances and the thermal-induced acceleration effect reduces. The buoyancy effect makes wall temperature at the top and bottom generatrices of the horizontal tube increase and decrease, respectively. Due to the coupled effect of the buoyancy and thermal-induced acceleration caused by the significant change of the properties, as the diameter increases, the heat transfer deteriorates dramatically at the top generatrix but remains almost unchanged at the bottom generatrix at high heat flux to mass flux ratio. Heat transfer enhancement is observed at low heat flux to mass flux ratio when the tube diameter is less than 6 mm. Moreover, the safety analysis has been performed in order to optimally design the supercritical cooling system.Peer reviewe

Propolis polyphenols: A review on the composition and anti-obesity mechanism of different types of propolis polyphenols

Obesity, one of the most common nutritional diseases worldwide, can lead to dyslipidemia, high blood sugar, high blood pressure, and inflammation. Some drugs have been developed to ameliorate obesity. However, these drugs may cause serious side effects. Therefore, there is an urgent need for alternative “natural” remedies including propolis. Studies have found that propolis has excellent anti-obesity activity in in vitro and in vivo models during the past decades, of which polyphenols are the key component in regulating weight loss. This review focused on the different polyphenol compositions of propolis from different regions and plants, the evidence for the anti-obesity effects of different types of propolis and its derivatives, discussed the impact of propolis polyphenols on obesity related signal pathways, and proposed the molecular mechanism of how propolis polyphenols affect these signal pathways. For example, propolis and its derivatives regulate lipid metabolism related proteins, such as PPARα, PPARγ, SREBP-1&2, and HMG CoA etc., destroy the formation of CREB/CRTC2 transcription complex, activate Nrf2 pathway or inhibit protein kinase IKK ε/TBK1, thereby affecting fat production and lipid metabolism; The effects of propolis on adipokines (adiponectin, leptin and inflammatory factors) were discussed. Additionally, the mechanism of polyphenols in propolis promoting the browning of adipose tissues and the relationship between intestinal microorganisms was summarized. These information may be of value to better understand how specific propolis polyphenols interact with specific signaling pathways and help guide the development of new drugs to combat obesity and related metabolic diseases

E-ffective: a visual analytic system for exploring the emotion andeffectiveness of inspirational speeches

What makes speeches effective has long been a subject for debate, and until today there is broad controversy among public speaking experts about what factors make a speech effective as well as the roles of these factors in speeches. Moreover, there is a lack of quantitative analysis methods to help understand effective speaking strategies. In this paper, we propose E-ffective, a visual analytic system allowing speaking experts and novices to analyze both the role of speech factors and their contribution in effective speeches. From interviews with domain experts and investigating existing literature, we identified important factors to consider in inspirational speeches. We obtained the generated factors from multi-modal data that were then related to effectiveness data. Our system supports rapid understanding of critical factors in inspirational speeches, including the influence of emotions by means of novel visualization methods and interaction. Two novel visualizations include E-spiral (that shows the emotional shifts in speeches in a visually compact way) and E-script (that connects speech content with key speech delivery information). In our evaluation we studied the influence of our system on experts' domain knowledge about speech factors. We further studied the usability of the system by speaking novices and experts on assisting analysis of inspirational speech effectiveness

SpeciFingers

The inadequate use of finger properties has limited the input space of touch interaction. By leveraging the category of contacting fingers, finger-specific interaction is able to expand input vocabulary. However, accurate finger identification remains challenging, as it requires either additional sensors or limited sets of identifiable fingers to achieve ideal accuracy in previous works. We introduce SpeciFingers, a novel approach to identify fingers with the capacitive raw data on touchscreens. We apply a neural network of an encoder-decoder architecture, which captures the spatio-temporal features in capacitive image sequences. To assist users in recovering from misidentification, we propose a correction mechanism to replace the existing undo-redo process. Also, we present a design space of finger-specific interaction with example interaction techniques. In particular, we designed and implemented a use case of optimizing the performance in pointing on small targets. We evaluated our identification model and error correction mechanism in our use case

Chlorogenic Acid Decreases Intestinal Permeability and Increases Expression of Intestinal Tight Junction Proteins in Weaned Rats Challenged with LPS

Chlorogenic acid, a natural phenolic acid present in fruits and plants, provides beneficial effects for human health. The objectives of this study were to investigate whether chlorogenic acid (CHA) could improve the intestinal barrier integrity for weaned rats with lipopolysaccharide (LPS) challenge. Thirty-two weaned male Sprague Dawley rats (21 ± 1 d of age; 62.26 ± 2.73 g) were selected and randomly allotted to four treatments, including weaned rat control, LPS-challenged and chlorogenic acid (CHA) supplemented group (orally 20 mg/kg and 50 mg/kg body). Dietary supplementation with CHA decreased (P<0.05) the concentrations of urea and albumin in the serum, compared to the LPS-challenged group. The levels of IFN-γ and TNF-α were lower (P<0.05) in the jejunal and colon of weaned rats receiving CHA supplementation, in comparison with the control group. CHA supplementation increased (P<0.05) villus height and the ratio of villus height to crypt depth in the jejunal and ileal mucosae under condictions of LPS challenge. CHA supplementation decreased (P<0.05) intestinal permeability, which was indicated by the ratio of lactulose to mannitol and serum DAO activity, when compared to weaned rats with LPS challenge. Immunohistochemical analysis of tight junction proteins revealed that ZO-1 and occludin protein abundances in the jejunum and colon were increased (P<0.05) by CHA supplementation. Additionally, results of immunoblot analysis revealed that the amount of occludin in the colon was also increased (P<0.05) in CHA-supplemented rats. In conclusion, CHA decreases intestinal permeability and increases intestinal expression of tight junction proteins in weaned rats challenged with LPS