3,496 research outputs found
Black Hole Shadows: How to Fix the Extended Gravity Theory
The first images of black hole shadows open new possibilities to develop
modern extended gravity theories. We discuss the shadow calculations in
non-rotating case both when and . We demonstrate the application to few different models: Horndesky
theory with Gauss-Bonnet invariant, loop quantum gravity and conformal gravity.
The difference of these theories from shadow models with the theory of general
relativity is shown. In addition we show that when the rotation is taken into
account the requirements to the observational accuracy decrease
Sintering oxide ceramics based on AI[2]O[3] and ZrO[2], activated by MgO, TiO[2] and SiO[2] additives
The positive effect of the addition of MgO and TiO[2] in an amount of no more than 1 wt. % on sintering and physico-mechanical properties of alumina ceramics is established. Addition of 5% of SiO[2] to A1[2]O[3] provides the mechanism of liquid phase sintering of ceramics, which leads to increase in its density and strength up to 480 MPa. In ceramic system A1[2]O[3] - ZrO[2] - Y[2]O[3] highest level of physical and mechanical properties of the composition had a hypereutectic composition 16.6% A1[2]O[3] - 76% Z1O[2] - 7.4% Y[2]O[3]. In this composition two mechanisms of hardening are realized simultaneously, such as transformational hardening by t-m -ZrO[2] transition and dispersion strengthening with high-modulus particles of [alpha]- A1[2]O[3]
Stromal and Tumor Glioma-Derived Cells with Similar Characteristics have Differences in α-Smooth Muscle Actin Expression and Localization
Gliomas are solid brain tumors composed of tumor cells and recruited heterogenic stromal components. The study of the interactions between the perivascular niche and its surrounding cells is of great value in unraveling mechanisms of drug resistance in malignant gliomas. In this study, we isolated the stromal diploid cell population from oligodendroglioma and a mixed population of tumor aneuploid and stromal diploid cells from astrocytoma specimens. The stromal cells expressed neural stem/progenitor and mesenchymal markers showing the same discordant phenotype that is typical for glioma cells. Moreover, some of the stromal cells expressed CD133. For the first time, we demonstrated that this type of stromal cells had the typical myofibroblastic phenotype as the α-SMA+ cells formed α-SMA fibers and exhibited the specific function to deposit extracellular matrix (ECM) proteins at least in vitro. Immunofluorescent analysis showed diffuse or focal α-SMA staining in the cytoplasm of the astrocytoma-derived, A172, T98G, and U251MG glioma cells. We could suggest that α-SMA may be one of the main molecules, bearing protective functions. Possible mechanisms and consequences of α-SMA disruptions in gliomas are discussed
Directions of Convergence of the Requirements of the Main Domestic Standard for the Design of Concrete and Reinforced Concrete Structures SP 63.13330.2012 with the Requirements of the International Standard ISO 19338
Design standards on building structures should contain, first of all, the performance and assessment requirements of structures. At the same time, design standards should provide the possibility for design and construction of concrete and reinforced concrete parts of buildings and structures that meet the requirements of the Technical regulations "On the safety of buildings and structures".
Taking into account the importance of ensuring the reliability and safety of buildings and structures erected with the use of structural concrete, the technical Committee of the international organization for standardization ISO TC 71 "Concrete, reinforced concrete and prestressed concrete", certifies national standards for compliance with the requirements of the international standard ISO 19338 "Performance and Assessment Requirements for Design Standards on Structural Concrete", developed by the same Committee.
The standard describes the issues that should be included in the standards for the design of concrete and reinforced concrete structures (terms and definitions, basic requirements, performance requirements,loads and impacts, design estimates, requirements for manufacturing and construction, as well as quality control). These requirements are common to all standards in the design of concrete and reinforced concrete structures.
In this regard, it is relevant and important to establish the possibility of presenting the National Code of rules SP 63.13330.2012 "SNiP 52.01-2003 Plain and Reinforced Concrete Structures. General Provisions" for certification for compliance with the requirements of ISO 19338. To achieve this goal, the relevant work has been done, based on the results of which were made the proposals for the submission of SP 63.13330.2012 for certification for compliance with ISO 19338:2014. These proposals are set out in the text of the article
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