catena-Poly[[[dichloridozinc(II)]-μ-1,4-bis­(1H-benzimidazol-2-yl-κN 3)butane] 1,4-bis­(1H-benzimidazol-2-yl)butane solvate]

In the crystal structure of the title coordination polymer/co-crystal, {[ZnCl2(C18H18N4)]·C18H18N4}n, the tetrahedrally coordinated ZnII ions are linked by the N-heterocycle into a linear chain. Another N-heterocycle present is not coordinated to the metal atom but inter­acts with the chain through N—H⋯N and N—H⋯Cl hydrogen bonds. The butyl chain of the uncoordinated ligand is disordered over three positions in a 0.511 (4):0.289 (5):0.200 (5) ratio

Advantages of Asynchronous Measurement-Device-Independent Quantum Key Distribution in Intercity Networks

The new variant of measurement-device-independent quantum key distribution (MDI-QKD), called asynchronous MDI-QKD or mode-pairing MDI-QKD, offers similar repeater-like rate-loss scaling but has the advantage of simple technology implementation by exploiting an innovative post-measurement pairing technique. We herein present an evaluation of the practical aspects of decoy-state asynchronous MDI-QKD. To determine its effectiveness, we analyze the optimal method of decoy-state calculation and examine the impact of asymmetrical channels and multi-user networks. Our simulations show that, under realistic conditions, aynchronous MDI-QKD can furnish the highest key rate with MDI security as compared to other QKD protocols over distances ranging from 50 km to 480 km. At fiber distances of 50 km and 100 km, the key rates attain 6.02 Mbps and 2.29 Mbps respectively, which are sufficient to facilitate real-time one-time-pad video encryption. Our findings indicate that experimental implementation of asynchronous MDI-QKD in intercity networks can be both practical and efficient

Experimental quantum secure network with digital signatures and encryption

Cryptography promises four information security objectives, namely, confidentiality, integrity, authenticity, and non-repudiation, to support trillions of transactions annually in the digital economy. Efficient digital signatures, ensuring the integrity, authenticity, and non-repudiation of data with information-theoretical security are highly urgent and intractable open problems in cryptography. Here, we propose a protocol of high-efficiency quantum digital signatures using secret sharing, one-time universal$_2$ hashing, and the one-time pad. We just need to use a 384-bit key to sign documents of up to $2^{64}$ lengths with a security bound of $10^{-19}$. If one-megabit document is signed, the signature efficiency is improved by more than $10^8$ times compared with previous quantum digital signature protocols. Furthermore, we build the first all-in-one quantum secure network integrating information-theoretically secure communication, digital signatures, secret sharing, and conference key agreement and experimentally demonstrate this signature efficiency advantage. Our work completes the cryptography toolbox of the four information security objectives.Comment: 19 pages, 7 figures, 4 tables. Quantum digital signatures and quantum private communication maintain a consistent level of practicalit

Mechanisms underlying Actinobacillus pleuropneumoniae exotoxin ApxI induced expression of IL-1β, IL-8 and TNF-α in porcine alveolar macrophages

Actinobacillus pleuropneumoniae (A. pleuropneumoniae) causes fibrino-hemorrhagic necrotizing pleuropneumonia in pigs. Production of proinflammatory mediators in the lungs is an important feature of A. pleuropneumoniae infection. However, bacterial components other than lipopolysaccharide involved in this process remain unidentified. The goals of this study were to determine the role of A. pleuropneumoniae exotoxin ApxI in cytokine induction and to delineate the underlying mechanisms. Using real-time quantitative PCR analysis, we found native ApxI stimulated porcine alveolar macrophages (PAMs) to transcribe mRNAs of IL-1β, IL-8 and TNF-α in a concentration- and time-dependent manner. Heat-inactivation or pre-incubation of ApxI with a neutralizing antiserum attenuated ApxI bioactivity to induce cytokine gene expression. The secretion of IL-1β, IL-8 and TNF-α protein from PAMs stimulated with ApxI was also confirmed by quantitative ELISA. In delineating the underlying signaling pathways contributing to cytokine expression, we observed mitogen-activated protein kinases (MAPKs) p38 and cJun NH2-terminal kinase (JNK) were activated upon ApxI stimulation. Administration of an inhibitor specific to p38 or JNK resulted in varying degrees of attenuation on ApxI-induced cytokine expression, suggesting the differential regulatory roles of p38 and JNK in IL-1β, IL-8 and TNF-α production. Further, pre-incubation of PAMs with a CD18-blocking antibody prior to ApxI stimulation significantly reduced the activation of p38 and JNK, and subsequent expression of IL-1β, IL-8 or TNF-α gene, indicating a pivotal role of β2 integrins in the ApxI-mediated effect. Collectively, this study demonstrated ApxI induces gene expression of IL-1β, IL-8 and TNF-α in PAMs that involves β2 integrins and downstream MAPKs

Simple security proof of coherent-one-way quantum key distribution

Coherent-one-way quantum key distribution (COW-QKD), which requires a simple experimental setup and has the ability to withstand photon-number-splitting attacks, has been not only experimentally implemented but also commercially applied. However, recent studies have shown that the current COW-QKD system is insecure and can only distribute secret keys safely within 20 km of the optical fiber length. In this study, we propose a practical implementation of COW-QKD by adding a two-pulse vacuum state as a new decoy sequence. This proposal maintains the original experimental setup as well as the simplicity of its implementation. Utilizing detailed observations on the monitoring line to provide an analytical upper bound on the phase error rate, we provide a high-performance COW-QKD asymptotically secure against coherent attacks. This ensures the availability of COW-QKD within 100 km and establishes theoretical foundations for further applications.Comment: 8 pages, 5 figures, 1 tabl

Sub-femtosecond electron bunches in laser wakefield acceleration via injection suppression with a magnetic field

It is shown that electron injection into a laser-driven plasma bubble can be manipulated by applying an external magnetic field in the presence of a plasma density gradient. The down-ramp of the density-tailored plasma locally reduces the plasma wave phase velocity, which triggers injection. The longitudinal magnetic field dynamically induces an expanding hole in the electron density distribution at the rear of the wake bubble, which reduces the peak electron velocity in its vicinity. Electron injection is suppressed when the electron velocity drops below the phase velocity, which depends on the size of the density hole. This enables the start and end of electron injection to be independently controlled, which allows generation of sub-femtosecond electron bunches with peak currents of a few kilo-Ampere, for an applied magnetic field of ∼ 10 Tesla

Beating the fault-tolerance bound and security loopholes for Byzantine agreement with a quantum solution

Byzantine agreement, the underlying core of blockchain, aims to make every node in a decentralized network reach consensus. Classical Byzantine agreements unavoidably face two major problems. One is $1/3$ fault-tolerance bound, which means that the system to tolerate $f$ malicious players requires at least $3f+1$ players. The other is the security loopholes from its classical cryptography methods. Here, we propose a strict quantum Byzantine agreement with unconditional security to break this bound with nearly $1/2$ fault tolerance due to multiparty correlation provided by quantum digital signatures. Our work strictly obeys the original Byzantine conditions and can be extended to any number of players without requirements for multiparticle entanglement. We experimentally demonstrate three-party and five-party quantum consensus for a digital ledger. Our work indicates the quantum advantage in terms of consensus problems and suggests an important avenue for quantum blockchain and quantum consensus networks.Comment: 22 pages, 10 figures. All comments are welcome