Performance and test section flow characteristics of the National Full-Scale Aerodynamics Complex 80- by 120-Foot Wind Tunnel

Results from the performance and test section flow calibration of the 80- by 120-Foot Wind Tunnel are presented. Measurements indicating the 80- by 120-ft test section flow quality were obtained throughout the tunnel operational envelope and for atmospheric wind speeds up to approximately 20 knots. Tunnel performance characteristics and a dynamic pressure system calibration were also documented during the process of mapping the test section flow field. Experimental results indicate that the test section flow quality is relatively insensitive to dynamic pressure and the level of atmospheric winds experienced during the calibration. The dynamic pressure variation in the test section is within +/-75 percent of the average. The axial turbulence intensity is less than 0.5 percent up to the maximum test section speed of 100 knots, and the vertical and lateral flow angle variations are within +/-5 deg and +/-7 deg, respectively. Atmospheric winds were found to affect the pressure distribution in the test section only at high ratios of wind speed to test section speed

Performance and test section flow characteristics of the National Full-Scale Aerodynamics Complex 40- by 80-foot wind tunnel

Results from the performance and test section flow calibration of the 40- by 80-Foot Wind Tunnel are presented. A flow calibration test was conducted in May and June 1987. The goal of the flow calibration test was to determine detailed spatial variations in the 40- by 80-ft test section flow quality throughout the tunnel operational envelope. Data were collected for test section speeds up to 300 knots and for air exchange rates of 0, 5, and 10 percent. The tunnel performance was also calibrated during the detailed mapping of the test section flow field. Experimental results presented indicate that the flow quality in the test section, with the exception of temperature, is relatively insensitive to the level of dynamic pressure and the air exchange rate. The dynamic pressure variation in the test section is within + or - 0.5 deg at all test section velocities. Cross-stream temperature gradients in the test section caused by the air exchange system were documented, and a correction method was established. Streamwise static pressure variation on the centerline is about 1 percent of test section dynamic pressure over 30 ft of the test section length

Aerodynamic surface distension system for high angle of attack forebody vortex control

A deployable system is introduced for assisting flight control under certain flight conditions, such as at high angles of attack, whereby two inflatable membranes are located on the forebody portion of an aircraft on opposite sides thereof. The members form control surfaces for effecting lateral control forces if one is inflated and longitudinal control forces if both are inflated

Capabilities, Performance, and Status of the SOFIA Science Instrument Suite

The Stratospheric Observatory for Infrared Astronomy (SOFIA) is an airborne observatory, carrying a 2.5 m telescope onboard a heavily modified Boeing 747SP aircraft. SOFIA is optimized for operation at infrared wavelengths, much of which is obscured for ground-based observatories by atmospheric water vapor. The SOFIA science instrument complement consists of seven instruments: FORCAST (Faint Object InfraRed CAmera for the SOFIA Telescope), GREAT (German Receiver for Astronomy at Terahertz Frequencies), HIPO (High-speed Imaging Photometer for Occultations), FLITECAM (First Light Infrared Test Experiment CAMera), FIFI-LS (Far-Infrared Field-Imaging Line Spectrometer), EXES (Echelon-Cross-Echelle Spectrograph), and HAWC (High-resolution Airborne Wideband Camera). FORCAST is a 540 m imager with grism spectroscopy, developed at Cornell University. GREAT is a heterodyne spectrometer providing high-resolution spectroscopy in several bands from 60240 m, developed at the Max Planck Institute for Radio Astronomy. HIPO is a 0.31.1 m imager, developed at Lowell Observatory. FLITECAM is a 15 m wide-field imager with grism spectroscopy, developed at UCLA. FIFI-LS is a 42210 m integral field imaging grating spectrometer, developed at the University of Stuttgart. EXES is a 528 m high-resolution spectrograph, developed at UC Davis and NASA ARC. HAWC is a 50240 m imager, developed at the University of Chicago, and undergoing an upgrade at JPL to add polarimetry capability and substantially larger GSFC detectors. We describe the capabilities, performance, and status of each instrument, highlighting science results obtained using FORCAST, GREAT, and HIPO during SOFIA Early Science observations conducted in 2011

The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel

Background: PB1-F2 is a proapoptotic influenza A virus protein of approximately 90 amino acids in length that is located in the nucleus, cytosol and in the mitochondria membrane of infected cells. Previous studies indicated that the molecule destabilizes planar lipid bilayers and has a strong inherent tendency for multimerization. This may be correlate with its capacity to induce mitochondrial membrane depolarization. Methodology/Principal Findings: Here, we investigated whether PB1-F2 is able to form ion channels within planar lipid bilayers and microsomes. For that purpose, a set of biologically active synthetic versions of PB1-F2 (sPB1-F2) derived from the IAV isolates A/Puerto Rico/8/34(H1N1)( IAV(PR8)), from A/Brevig Mission/1/1918( H1N1) (IAV(SF2)) or the H5N1 consensus sequence (IAV(BF2)) were used. Electrical and fluorimetric measurements show that all three peptides generate in planar lipid bilayers or in liposomes, respectively, a barely selective conductance that is associated with stochastic channel type fluctuations between a closed state and at least two defined open states. Unitary channel fluctuations were also generated when a truncated protein comprising only the 37 c-terminal amino acids of sPB1-F2 was reconstituted in bilayers. Experiments were complemented by extensive molecular dynamics simulations of the truncated fragment in a lipid bilayer. The results indicate that the c-terminal region exhibits a slightly bent helical fold, which is stable and remains embedded in the bilayer for over 180 ns. Conclusion/Significance: The data support the idea that PB1-F2 is able to form protein channel pores with no appreciable selectivity in membranes and that the c-terminus is important for this function. This information could be important for drug development