3 research outputs found
Study of Diluted Meldonium Solutions by Surface Enhanced Raman Scattering Spectroscopy
Silvered porous silicon was utilized as an active substrate for a detection of small amounts of meldonium by surface enhanced Raman scattering (SERS) spectroscopy. We were able to detect the meldonium in its water solutions at the concentrations of 102β106 M. Immersion of the silvered porous silicon in the meldonium solutions at the 104M concentration and lower led to the dimers' formation. At the concentrations larger than 103 M, a greater contribution to the enhancement of the Raman intensity was caused by a chemical mechanism while the smaller amounts were detected mostly due to an electromagnetic mechanism
High rate dose brachytherapy - HDR experience for localized and locally advanced prostate cancer in Sverdlovsk Regional Oncology Dispensary
Currently, the rate of morbidity and mortality from prostate cancer has been increasing. HDR brachytherapy (HDR-ΠΠ’) is considered to be one of the modern methods in the treatment of prostate cancer. In Sverdlovsk Regional Oncology Centre (SROC) this method has been being applied since 2009. In our work we analyzed treatment outcomes in 204 patients with localized and locally advanced prostate cancer after HDR as a single method as well as a part of combined and complex treatment. Our results evidenced of HDR brachytherapy as an effective and safe method of treatment, which improves hospitalization.Π Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ Π² Π ΠΎΡΡΠΈΠΈ ΠΎΡΠΌΠ΅ΡΠ°Π΅ΡΡΡ ΡΠΎΡΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΠΈ ΠΈ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ ΠΎΡ ΡΠ°ΠΊΠ° ΠΏΡΠ΅Π΄ΡΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ. ΠΠ΄Π½ΠΈΠΌ ΠΈΠ· ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ Π²Π½ΡΡΡΠΈΡΠΊΠ°Π½Π΅Π²Π°Ρ Π²ΡΡΠΎΠΊΠΎΠ΄ΠΎΠ·Π½Π°Ρ Π±ΡΠ°Ρ
ΠΈΡΠ΅ΡΠ°ΠΏΠΈΡ - HDR (High dose rate). Π Π‘Π²Π΅ΡΠ΄Π»ΠΎΠ²ΡΠΊΠΎΠΌ ΠΎΠ±Π»Π°ΡΡΠ½ΠΎΠΌ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌ Π΄ΠΈΡΠΏΠ°Π½ΡΠ΅ΡΠ΅ (Π‘ΠΠΠ) ΡΡΠΎΡ ΠΌΠ΅ΡΠΎΠ΄ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΡΡΡ Ρ 2009 Π³. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡΡΡ Π°Π½Π°Π»ΠΈΠ· ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ 204 Π±ΠΎΠ»ΡΠ½ΡΡ
Π»ΠΎΠΊΠ°Π»ΡΠ½ΡΠΌ ΠΈ ΠΌΠ΅ΡΡΠ½ΠΎ-ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΡΠΌ ΡΠ°ΠΊΠΎΠΌ ΠΏΡΠΎΡΡΠ°ΡΡ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ HDR ΠΊΠ°ΠΊ Π² ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎΠΌ ΠΏΠ»Π°Π½Π΅, ΡΠ°ΠΊ ΠΈ Π² ΡΠΎΡΡΠ°Π²Π΅ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΈ/ΠΈΠ»ΠΈ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π½Π°ΠΌΠΈ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΡΡ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ Π²ΡΡΠΎΠΊΠΎΠ΄ΠΎΠ·Π½Π°Ρ Π±ΡΠ°Ρ
ΠΈΡΠ΅ΡΠ°ΠΏΠΈΡ - HDR ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌ ΠΈ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΡΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ Π»Π΅ΡΠ΅Π½ΠΈΡ, Π½Π΅ ΡΡΠ΅Π±ΡΡΡΠΈΠΌ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΡΠΎΠΊΠΎΠ² Π³ΠΎΡΠΏΠΈΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
Postoperative early complications and mortality in patients with bladder cancer undergoing radical cystectomy
Radical cystectomy is the standard of care for muscle invasive and re-fractory or recurrent noninvasive bladder cancer. Unfortunately, despite of the recent improvements, radical cystectomy is still associated with high risk of perioper-ative complications and non-negligible risk of mortality. The aim of the present study was evaluation 30-days perioperative complications and mortality rate in our single-center series of radical cystectomy cases based on standardized Clavien-Dindo classification.Π Π°Π΄ΠΈΠΊΠ°Π»ΡΠ½Π°Ρ ΡΠΈΡΡΡΠΊΡΠΎΠΌΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΡΠ°Π½Π΄Π°ΡΡΠΎΠΌ Π»Π΅ΡΠ΅Π½ΠΈΡ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΠΌΠΈ ΠΈ ΡΠ΅ΡΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠΌΠΈ ΠΊ ΠΎΡΠ³Π°Π½ΠΎΡΠΎΡ
ΡΠ°Π½ΡΡΡΠ΅ΠΌΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΠ΅ΡΠΈΠ΄ΠΈΠ²Π½ΡΠΌΠΈ Π½Π΅ ΠΌΡΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΠΌΠΈ ΡΠΎΡΠΌΠ°ΠΌΠΈ ΡΠ°ΠΊΠ° ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ. Π ΡΠΎΠΆΠ°Π»Π΅Π½ΠΈΡ, Π½Π΅ΡΠΌΠΎΡΡΡ Π½Π° ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΠ΅ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ, ΡΠ°Π΄ΠΈΠΊΠ°Π»ΡΠ½Π°Ρ ΡΠΈΡΡΡΠΊΡΠΎΠΌΠΈΡ ΠΏΠΎ-ΠΏΡΠ΅ΠΆΠ½Π΅ΠΌΡ Π°ΡΡΠΎΡΠΈΠΈΡΡΠ΅ΡΡΡ Ρ Π²ΡΡΠΎΠΊΠΈΠΌ ΡΠΈΡΠΊΠΎΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΈ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ. Π¦Π΅Π»ΡΡ Π½Π°ΡΡΠΎΡΡΠ΅Π³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ»Π°ΡΡ ΠΎΡΠ΅Π½ΠΊΠ° 30-ΡΠΈ Π΄Π½Π΅Π²Π½ΡΡ
ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΈ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ Π² Π½Π°ΡΠ΅ΠΉ ΠΎΠ΄Π½ΠΎΡΠ΅Π½ΡΡΠΎΠ²ΠΎΠΉ ΡΠ΅ΡΠΈΠΈ ΡΠ°Π΄ΠΈΠΊΠ°Π»ΡΠ½ΡΡ
ΡΠΈΡΡΡΠΊΡΠΎΠΌΠΈΠΉ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΡΠ°Π½Π΄Π°ΡΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΊΠ»Π°ΡΡΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ ΠΠ»Π°Π²ΡΠ΅Π½-ΠΠΈΠ½Π΄ΠΎ