Impact of Psychological Problems and Marital Adjustment of Iranian Veterans on Their Children's Quality of Life and Happiness

Background: The Iran-Iraq war during the 1980-1988 has left many consequences on veterans and their families that persist long after the war ended. Objectives: The aim of this study was to evaluate the impact of psychological problems and marital adjustment of Iranian veterans on their children's quality of life and happiness 24 years after the war ended. Patients and Methods: The sample was all children of veterans in Isfahan city that registered by Veterans and Martyrs Affair Foundation (VMAF). One hundred sixty-three veterans were selected by systematic randomized sampling and the symptom checklist-90-revised (SCL-90-R) and dyadic adjustment scale (DAS) were administered for them. Their wives filled out the DAS and their children answered to World Health Organization Quality of Life-Brief version (WHOQOL-BREF) and Oxford Happiness Inventory (OHI). The data from questionnaires completed by 149 families were analyzed using the multiple regressions analysis. Results: Global Severity Index (GSI) scores of veterans and veteran's age were inversely correlated with the scores of children's quality of life, while marital adjustment of parents and number of rooms in house were positively correlated. Mother's age was inversely correlated with the scores of children's happiness, while marital adjustment of the parents, the number of rooms in their house and the number of children were positively correlated. Conclusions: In veterans' family, psychological health of the veterans and marital adjustment of the parents have a significant relationship with their children's quality of life and happiness

Effect of Mindfulness-Based Stress Reduction on Pain Severity and Mindful Awareness in Patients With Tension Headache: A Randomized Controlled Clinical Trial

Background: Programs to improve the pain and health status in illnesses with pain such as headache are still in their infancy. Mindfulness-based stress reduction (MBSR) is a new psychotherapy that appears to be effective in treating chronic pain. Objectives: This study evaluated efficacy of MBSR in improving pain severity and mindful awareness in patients with tension headache. Patients and Methods: This study was a randomized controlled clinical trial that was conducted in 2012 in Shahid Beheshti Hospital of Kashan City. Sixty patients who were diagnosed with tension-type headache according to the International Headache Classification Subcommittee were randomly assigned to treatment as usual (TAU) or MBSR groups. The MBSR group received eight weekly treatments. Any session lasted 120 minutes. The sessions were based on MBSR protocol. Diary scale for measuring headache and Mindful Attention Awareness Scale (MAAS) were administered at pretreatment, and posttreatment, and three-month follow-up in both groups. The data was analyzed using repeated measures analysis of variance. Results: The mean of pain severity was 7.36 ± 1.25 before intervention that was significantly reduced to 5.62 ± 1.74 and 6.07 ± 1.08 after the intervention and follow-up (P < 0.001). In addition, the MBSR group showed higher scores in mindful awareness in comparison with the control group at posttest session. The mean of mindful awareness before intervention was 34.9 ± 10.5 and changed to 53.8 ± 15.5 and 40.7 ± 10.9 after the intervention and follow-up sessions (P < 0.001). Conclusions: MBSR could reduce pain and improve mindfulness skills in patients with tension headache. It appears that MBSR is an effective psychotherapy for treatment of patients with tension headache

Effect of Mindfulness-Based Stress Reduction on Anxiety, Depression and Stress in Women With Multiple Sclerosis

Background: Studies suggest that mindfulness-based interventions can improve anxiety, depression and stress in patients with multiple sclerosis (MS). However, no study investigated the effectiveness of this method in patients with a combination of problems such as depression, anxiety and stress simultaneously. However, comorbidities of depression and anxiety in MS are prevalent. Objectives: This study aimed to assess the effects of mindfulness-based stress reduction (MBRS) on anxiety, depression and stress in women with multiple sclerosis. Patients and Methods: This randomized controlled clinical trial was performed in 2013 in Ahvaz MS Society. Forty eight patients were selected by convenient sampling and randomly assigned in experimental and control groups. The patients in the two groups filled out depression, anxiety and stress scale (DASS-21) at initiation of study, 8 weeks later and 1 month after the end of intervention. The experimental group received 8 sessions of MBRS, while the control group treated as usual. Finally, data of 40 patients analyzed using t-test, chi square and repeated measures analysis of variance. Results: In the MBSR group, the mean depression, anxiety and stress were reduced significantly (P < 0.001). The mean depression score was 8.35 ± 1.78 before the intervention and reduced to 4.80 ± 0.83 and 4.45 ± 0.60 after the intervention and follow-up (P < 0.001). Also the mean anxiety score was 8.90 ± 1.97 before the intervention, which was significantly reduced to 4.70 ± 1.38 and 4.55 ± 0.99 after the intervention and follow-up (P < 0.001). The mean stress score was also 8.80 ± 2.35 before treatment and 4.80 ± 1.67 and 4.70 ± 1.34 after the intervention and follow-up (P < 0.001). Conclusions: This study showed that MBSR training can reduce mean depression, anxiety and stress scores in patients with MS. These findings suggest that MBSR is useful for psychological problems such as depression, anxiety and stress in patients with MS

Effects of mindful parenting training on clinical symptoms in children with attention deficit hyperactivity disorder and parenting stress: Randomized controlled trial

Abstract Background: Children with attention deficit hyperactivity disorder (ADHD) are at risk of impairment in multiple domains. This study aimed to investigate the effectiveness of mindful parenting training in reducing clinical symptoms in children with ADHD and parenting stress of their parents. Methods: This randomized clinical trial was conducted on 2 groups (experimental and control) in 3 phases (pretest, posttest, and 8 weeks’ follow-up). Sixty children with ADHD, who had been referred by the child psychiatrist in the Iranian city of Kashan in the second half of the year 2016, were selected along with their mothers. The mothers were assigned to one of the 2 groups via permuted blocked randomization. The mothers completed the parenting stress index–short form (PSI–SF 36) and the Swanson, Nolan, and Pelham Parent and Teacher rating scale (SNAP-IV). All the children in both groups received pharmacotherapy with either risperidone or Ritalin. The intervention group received 8 sessions (1 session each week, each session lasting 90 minutes) of mindful parenting training based on the Kabat-Zinn protocol. The data were analyzed using SPSS, version 20, via the t test, χ2 test, repeated measures analysis of variance, and nonparametric Friedman test. Results: This study showed a reduction in parenting stress, negative parent-child interactions, and children’s problematic characteristics in the mindful parenting training group compared with the control group in the posttest and follow-up. Our results also demonstrated a significant improvement in ADHD symptoms in the experimental group by comparison with the control group in the posttest and follow-up. Conclusion: Mindful parenting training was effective in reducing parenting stress and ADHD symptoms in our intervention group. Keywords ● Mindfulness ● Attention deficit disorder with hyperactivity ● Parenting ● Stress ● Physiologica

Efficacy of Mindfulness-Based Stress Reduction on Mood States of Veterans With Post-Traumatic Stress Disorder

Background: Mood and negative emotional states and their regulation in patients with post-traumatic stress disorder have family, social and employment problems. Practices that could be helpful in this area are highly important. Objectives: The current study aimed to investigate the influence of mindfulness-based stress reduction (MBSR) in improving mood state of combat veterans. Patients and Methods: In this randomized clinical trial study, participants were selected from the patients referring to the counseling center of the veterans. The participants had post-traumatic stress disorder according to diagnostic and statistical manual of mental disorders, fourth edition, text review (DSM-IV-TR). Sixty- two patients were randomly assigned into 2 groups: (31 for MBSR and 31 for the control group). Results: Analysis showed that there were no significant differences between the groups at baseline (P < 0.05). Comparison of the results between the two groups before the two-step test showed that anger and vitality scales between the two groups have no significant differences, but on the other scales (depression, dizziness, fatigue and tension), differences between pre and post-test groups were significant in the two groups. Conclusions: It was concluded that mindfulness-based stress reduction is a useful method to regulate the mood state in veterans with post-traumatic stress disorder (PTSD) who have difficulties in mood and emotions in Kashan

Experimental pathology of Streptococcus sp. in Rainbow Trout, Oncorhynchus mykiss

Experimental pathology of Streptococcus sp. was studied in Rainbow Trout weighing 18-20 grams each using bath (1.5t10 ^(3) 1.5t10 ^ (4), 1.5t10 ^ (5), 1.5t10 ^ (6) 1.5t10 ^ (7).5t10 ^ (8) cell/ml for one hour) and intraperitoneal (1.5t10 ^ (3) 1.5t10 ^ (4) 1.5t10 ^ (5), 1.5t10 ^ (6), 1.5t10 ^ (7) 1.5t10 ^ (8) cell/fish) challenges provided at 18C. Control groups were included by intraperitoneal injection of fish with sterile phosphate buffered saline (0.5 ml/fish) after anesthetizing fish with clove oil (100 mg/l). Six groups consisting of 12 fish each were used. No morbidity or mortality occurred in bath-immersion groups, while mortality occurred in intraperitoneally injected fish 24 hours post-challenge and reached LD _(50) at 1.5tl0 ^ (8) cell/fish 72 hours post-challenge. The affected fish showed anorexia, darkening of body, exophthalmia, and prolapsed anal abdominal distension. In histopathological sections, there were hyperemia and sinusoidal congestion plus necrosis and degeneration of liver hepatocytes. Also, hyperemia in heart tissue, an increase in interstitial tissue plus necrosis of kidney tubular, edema of Bowman capsules together with an increase in melano macrophage centers of kidney tissues were seen. In addition, congestion of spleen ellipsoids and necrosis of spleen cells were observable. Detachment of basal membrane of secondary lamella with infiltration of inflammatory cells, congestion and edema of menangial layers, hemorrhage in orbital adipose tissue and destruction of eye cornea were also observable

Comparing Cognitive Failures and Metacognitive Beliefs in Mild Traumatic Brain Injured Patients and Normal Controls in Kashan

Background: Head trauma is associated with multiple destructive cognitive symptoms and cognitive failure. Cognitive failures include problems with memory, attention and operation. Cognitive failures are considered as a process associated with metacognition. Objectives: This study aimed to compare cognitive failures and metacognitive beliefs in mild Traumatic Brain Injured (TBI) patients and normal controls in Kashan. Patients and Methods: The study was performed on 40 TBI patients referred to the Shahid Beheshti Hospital of Kashan city and 40 normal controls in Kashan. Traumatic brain injured patients and normal controls were selected by convenience sampling. Two groups filled out the demographic sheet, Cognitive Failures Questionnaire (CFQ) and Meta-Cognitions Questionnaire 30 (MCQ-30). The data were analyzed by the SPSS-19 software with multivariate analysis of variance. Results: The results of this study showed that there were no significant differences between TBI and controls in total scores and subscales of CFQ and MCQ (F = 0.801, P = 0.61). Conclusions: Based on these findings, it seems that mild brain injuries don't make significant metacognitive problems and cognitive failures

Synthesis of the erythromycin-conjugated nanodendrimer and its antibacterial activity

Abstract The development and spread of bacterial resistance to antimicrobial drugs necessitates the need to search for novel and effective antimicrobial agents. In the last few decades, innovative nanomaterials are attracting increasing attention and, among them, dendrimers have shown wide application in the various fields. In the current study, the two generations of an anionic linear- spherical nanodendrimer G1 and G2 were synthetized and compound G2 of nanodendrimer conjugated with erythromycin. The structures of the nanodendrimers were characterized by FTIR spectroscopy, zetasizer, and scanning electron microscopy (SEM). The antibacterial activity of the erythromycin-conjugated nanodendrimer and erythromycin alone were evaluated by the microdilution method against Staphylococcus aureus, S. epidermidis, S. saprophyticus, and Pseudomonas aeruginosa. The size of first and second generation of nanodendrimer, and the erythromycin-conjugated nanodendrimer was 75, 95, and 65.6 nm, respectively. The drug loading percentage of the nanodendrimer conjugates was obtained to be in 35.2%. In our study, the erythromycin-conjugated nanodendrimer showed significantly more bacteriostatic and bactericidal activities against all four studied bacteria than erythromycin alone. Our study's results highlight that the erythromycin-conjugated nanodendrimer is a highly effective agent against Gram positive and negative bacteria. The antibacterial properties of erythromycin combined with the targeting potential of the nanodendrimer can lead to sustained intracellular delivery of therapeutic agent Keywords: Nanostructures Erythromycin Dendrimers Antibacterial agents

Personality Types and Emotional Intelligence as Predictors of Academic Achievement in Students at Kashan University of Medical Sciences

Background: Type of personality and emotional intelligence affects a person’s mental function and capabilities, which can influence academic achievement. Objectives: This study was designed to evaluate the relationship between emotional intelligence, type of character and academic achievement. Materials and Methods: This is a cross-sectional study on students of Kashan University of Medical Sciences in 2012. In total 221 students participated in the study. In addition to demographic information, a Five Factor Personality Questionnaire and Emotional Quotient Inventory were used. Participants completed questionnaires in their classrooms. Data were analyzed using SPSS software version 16. Descriptive statistics were calculated and analysis of variance and regression analysis were used. Results: Students in the various disciplines were not statistically different in terms of personality. Students with different grade point averages were significantly different in relation to: problem-solving, happiness, self-actualization, optimism, self-respect, flexibility and total emotional quotient (EQ) scores (P < 0.05). However, no statistically significant differences were observed between personality types in students with different grade point average. All variables (EQ, agreeableness, extroversion, openness, consciousness) except neuroticism were excluded from the regression model. Conclusions: Some components of personality types and emotional intelligence are predictors of academic achievement. Therefore, attention to these issues in students is needed to ensure the best achievement gains