A dual simplex-based method for determination of the right and left returns to scale in DEA

This study reviews the concept of the "right" and the "left" returns to scale (RTS) in data envelopment analysis (DEA), and a dual simplex-based method, for determining these two notions in RTS, is proposed, which has computational advantages as compared to the customary method.DEA Returns to scale Linear programming Dual-simplex algorithm

A Moment-Based Approach For Dvh-Guided Radiotherapy Treatment Plan Optimization

The dose-volume histogram (DVH) is a clinically relevant criterion to evaluate the quality of a treatment plan. It is hence desirable to incorporate DVH constraints into treatment plan optimization for intensity modulated radiation therapy. Yet, the direct inclusion of the DVH constraints into a treatment plan optimization model typically leads to great computational difficulties due to the non-convex nature of these constraints. To overcome this critical limitation, we propose a new convex-moment-based optimization approach. Our main idea is to replace the non-convex DVH constraints by a set of convex moment constraints. In turn, the proposed approach is able to generate a Pareto-optimal plan whose DVHs are close to, or if possible even outperform, the desired DVHs. In particular, our experiment on a prostate cancer patient case demonstrates the effectiveness of this approach by employing two and three moment formulations to approximate the desired DVHs. © 2013 Institute of Physics and Engineering in Medicine