Can conditional transfers eradicate child marriage?

Conditional cash transfers are increasingly being used by policymakers as a strategy to postpone the marriage of adolescent girls in developing countries. While this approach has met with success in the case of education and health programmes, it is unlikely, on its own, to address deeper issues related to child marriage, such as the agency of adolescent girls in their marriage decisions, sexual rights within marriage, and social norms within their own communities. We argue for a multi-dimensional, longer-term and holistic view of impact, that takes into account dimensions such as realized rights, health and access to education rather than cost-benefit based approaches that rely on single-focus indicators

Adsorptive Power Evaluation of the Nano-Crystalline Mo-W Bimetallic Oxides

Novel nanosized molybdenum-tungsten bimetallic oxides were prepared by modified Pechini method based on the low temperature polymerization-complexation steps. The physical properties of the prepared nanoparticles were characterized by: X-ray diffraction (XRD), Fourier transformer inferred spectroscopy (FT-IR), differential thermal analyses (DCS), and high resolution transmission electron microscopy (HRTEM). The influence of metal molar ratios (Mo/W) on the morphology and the crystallization the samples was also investigated. The adsorptive power of prepared samples was evaluated through the removal of dimethyl disulfide sulfur compound (in cyclohexane as fuel). The results indicate that all the prepared Mo-W oxide materials are nanoparticles with diameter ranging between 1 and 70 nm. And the smallest nanosize particles enhanced the adsorptive power of the prepared nanostructured Mo-W bimetallic oxide. Keywords : Mixed Oxide, Synthesis, Characterization, Sulfur Adsorption

A simple Simulation Model for Oxidative Coupling of Methane over La0.6Sr0.4NiO3 Nanocatalyst.

La0.6Sr0.4NiO3 perovskite-type oxides were prepared by reverse microemulsion method aided by ultrasonic homogenizer. The mixed oxide precursors and the corresponding derived fresh catalysts were characterized by thermogravimetry and differential thermal analysis (TG/DTA), X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET) surface area and high resolution transmission electron microscope (HRTEM). XRD results reveal that pure phase of perovskite-type crystalline structure was obtained for all samples and the electronic unbalance caused by the partial substitution for La3+ by Sr2+ is compensated by oxidation of a fraction of Ni3+ to Ni4+ and/or generation of oxygen vacancies in the perovskite lattice. There exist two kinds of oxygen species on the oxides: surface adsorption oxygen and bulk lattice oxygen. The surface oxygen contributed to oxidize methane completely to CO2 and H2O because of its higher reactivity, while the other one prone to oxidative coupling of methane into C2H6 and C2H2 (C2+).  In this study a mathematical model for the oxidative coupling of methane (OCM) over La0.6Sr0.4NiO3 pervoskite is developed. From this simulation it can predict that the activity at temperature ? 925 ºC and methane partial pressure =0.3 and oxygen partial pressure =0.1 will be reach ~10% and selectivity ~50%. Keywords: Oxidative coupling, Methane, Perovskit

Anesthesiology Resident Performance on the US Medical Licensing Examination Predicts Success on the American Board of Anesthesiology BASIC Staged Examination: An Observational Study

BACKGROUND: Correlation has been found between the US Medical Licensing Examination (USMLE) Step 1 examination results and anesthesiology resident success on American Board of Anesthesiology (ABA) examinations. In 2014, the ABA instituted the BASIC examination at the end of the postgraduate year-2 year. We hypothesized a similar predictive value of USMLE scores on BASIC examination success. METHODS: After the Committee for the Protection of Human Subjects at UTHealth Institutional Review Board approved and waived written consent, we retrospectively evaluated USMLE Step examination performance on first-time BASIC examination success in a single academic department from 2014-2018. RESULTS: Over 5 years, 120 residents took the ABA BASIC examination and 108 (90%) passed on the first attempt. Ten of 12 first-time failures were successful on repeat examination but analyzed in the failure group. Complete data was available for 92 residents (76.7%), with absent scores primarily reflecting osteopathic graduates who completed Comprehensive Osteopathic Medical Licensing Examination of the United States level examinations rather than USMLE. In the failure cohort, all 3 USMLE examination step scores were lower ( CONCLUSIONS: In anesthesiology residency training, our preliminary single-center data is the first to suggest that USMLE Step 1 performance could be used as a predictor of success on the recently introduced ABA BASIC Examination. These findings do not support recent action to change USMLE scoring to a pass/fail report

Physiological Changes and Interactions Between Microbiome and the Host During Pregnancy

In recent years, it has become clear that microbiome play a variety of essential roles in human metabolism, immunity, and overall health and that the composition of these microbiome is influenced by our environment, diet, weight, hormones, and other factors. Indeed, numerous physiological and pathological conditions, including obesity and metabolic syndrome, are associated with changes in our microbiome, referred to as dysbiosis. As a result, it is not surprising that such changes occur during pregnancy, which includes substantial weight gain and significant changes in metabolism and immune defenses. The present review relates physiological changes during pregnancy to alterations in the microbial composition at various sites, including the gut, oral cavity, and vagina. Pregnancy has been linked to such microbial changes, and we believe that, in contrast to certain disease states, these microbial changes are vital for a healthy pregnancy, probably through their influence on the mother’s immunological, endocrinological, and metabolic status.This research was funded by Qatar National Research Fund (QNRF), grant number UREP26-104-3-044

Assessment of Allergic Rhinitis among Children after Low-Level Laser Therapy

BACKGROUND: Allergic rhinitis (AR) represents one of the most common global health problems with seriously increasing incidence over the last decades. The goal of the treatment of rhinitis is to prevent or reduce the symptoms caused by the inflammation of affected tissues. Intranasal steroids and oral antihistamines are recommended as first lines of treatment. Acupuncture had reported a significant improvement in daily symptoms and an increase of symptom-free days in many studies enrolling adults’ patients.AIM: This study aimed to evaluate the laser acupuncture effect on the treatment of children AR in comparison to the effect of the medication and to assess the anti-inflammatory effect of laser acupuncture through measurement of serum inflammatory marker (hs-CRP). METHODS: Sixty patients with allergic rhinitis their age group ranged from 4 to 18 years were divided randomly into two groups. Group 1 enrolled 30 patient that received AR in the form of intranasal steroids, antihistaminic, leukotriene antagonists while group2 thirty patients received 12 laser acupuncture sessions (2 sessions a \ week) on specific traditional Chinese acupuncture points.RESULTS: There was a significant improvement in the severity score symptoms in both groups through and by the end of the study. High Significant improvement in the levels of the inflammatory marker in both groups, especially in the group which receive laser acupuncture sessions.CONCLUSION: Laser acupuncture is a reliable, painless and non-invasive successful technique, which may be used as a complementary treatment for pediatric allergic rhinitis

World Stroke Organization Brain & hEart globAl iniTiative Program

Introduction. The World Stroke Organization (WSO) Brain & Heart Task Force developed The Brain & hEart globAl iniTiative (BEAT), a pilot feasibility implementation program aimed at establishing clinical collaborations between cardiologists and stroke physicians who work at large healthcare facilities. Methods. The WSO BEAT pilot project focused on atrial fibrillation (AF) and patent foramen ovale (PFO) detection and management, and post-stroke cardiovascular complications known as the stroke-heart syndrome. The program included 10 sites from 8 countries: Brazil, China, Egypt, Germany, Japan, Mexico, Romania, and the USA. The primary composite feasibility outcome was the achievement of the following 3 implementation metrics (1) developing site-specific clinical pathways for the diagnosis and management of AF, PFO, and the stroke heart syndrome; (2) establishing regular Neurocardiology rounds (e.g., monthly); and (3) incorporating a cardiologist to the stroke team. The secondary objectives were (1) to identify implementation challenges to guide a larger program and (2) to describe qualitative improvements.Results. The WSO BEAT pilot feasibility program achieved the pre-specified primary composite outcome in 9 of 10 (90%) sites. The most common challenges were the limited access to specific medications (e.g., direct oral anticoagulants) and diagnostic (e.g., prolonged cardiac monitoring) or therapeutic (e.g., PFO closure devices) technologies. The most relevant qualitative improvement was the achievement of a more homogeneous diagnostic and therapeutic approach.Discussion/Conclusion. The WSO BEAT pilot program showed that developing Neurocardiology collaborations is feasible. The long-term sustainability of the WSO BEAT program and its impact on quality of stroke care and clinical outcomes needs to be tested in a larger and longer-duration program

The MKK7-MPK6 MAP Kinase Module Is a Regulator of Meristem Quiescence or Active Growth in Arabidopsis

Plant growth flexibly adapts to environmental conditions. Growth initiation itself may be conditional to a suitable environment, while the most common response of plants to adverse conditions is growth inhibition. Most of our understanding about environmental growth inhibition comes from studies on various plant hormones, while less is known about the signaling mechanisms involved. The mitogen-activated protein kinase (MAPK) cascades are central signal transduction pathways in all eukaryotes and their roles in plant stress responses is well-established, while increasing evidence points to their involvement in hormonal and developmental processes. Here we show that the MKK7-MPK6 module is a suppressor of meristem activity using genetic approaches. Shoot apical meristem activation during light-induced de-etiolation is accelerated in mpk6 and mkk7 seedlings, whereas constitutive or induced overexpression of MKK7 results in meristem defects or collapse, both in the shoot and the root apical meristems. These results underscore the role of stress-activated MAPK signaling in regulating growth responses at the whole plant level, which may be an important regulatory mechanism underlying the environmental plasticity of plant development

Drought Severity and Frequency Analysis Aided by Spectral and Meteorological Indices in the Kurdistan Region of Iraq

In the past two decades, severe drought has been a recurrent problem in Iraq due in part to climate change. Additionally, the catastrophic drop in the discharge of the Tigris and Euphrates rivers and their tributaries has aggravated the drought situation in Iraq, which was formerly one of the most water-rich nations in the Middle East. The Kurdistan Region of Iraq (KRI) also has catastrophic drought conditions. This study analyzed a Landsat time-series dataset from 1998 to 2021 to determine the drought severity status in the KRI. The Modified Soil-Adjusted Vegetation Index (MSAVI2) and Normalized Difference Water Index (NDWI) were used as spectral-based drought indices to evaluate the severity of the drought and study the changes in vegetative cover, water bodies, and precipitation. The Standardized Precipitation Index (SPI) and the Spatial Coefficient of Variation (CV) were used as meteorologically based drought indices. According to this study, the study area had precipitation deficits and severe droughts in 2000, 2008, 2012, and 2021. The MSAVI2 results indicated that the vegetative cover decreased by 36.4%, 39.8%, and 46.3% in 2000, 2008, and 2012, respectively. The SPI’s results indicated that the KRI experienced droughts in 1999, 2000, 2008, 2009, 2012, and 2021, while the southeastern part of the KRI was most affected by drought in 2008. In 2012, the KRI’s western and southern parts were also considerably affected by drought. Furthermore, Lake Dukan (LD), which lost 63.9% of its surface area in 1999, experienced the most remarkable shrinkage among water bodies. Analysis of the geographic distribution of the CV of annual precipitation indicated that the northeastern parts, which get much more precipitation, had less spatial rainfall variability and more uniform distribution throughout the year than other areas. Moreover, the southwest parts exhibited a higher fluctuation in annual spatial variation. There was a statistically significant positive correlation between MSAVI2, SPI, NDWI, and agricultural yield-based vegetation cover. The results also revealed that low precipitation rates are always associated with declining crop yields and LD shrinkage. These findings may be concluded to provide policymakers in the KRI with a scientific foundation for agricultural preservation and drought mitigation

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London