598 research outputs found

    The SPAD chlorophyll meter: a potential rapid, nondestructive method of leaf N monitoring in lentil

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    Non-Peer ReviewedThe SPAD Chlorophyll Meter (SPAD) measures the chlorophyll content of leaves, and can be used to estimate the nitrogen status of plants as an alternative to the nitrate tissue test. The leaf nitrogen monitoring in experimental plots consists of sampling, drying, weighing, grinding and finally the N measurement of the leaves. Data obtained in some crops like wheat, maize, barley and peanut from the SPAD chlorophyll meter showed reasonable estimation of leaf nitrogen characters (LNCs): %leaf N, specific leaf weight (SLW) and specific leaf nitrogen (SLN). Leaf color and the resulting SPAD reading however, may vary by cultivar, soil and air temperature; planting date, leaf stage, leaf position, plant disease, nutrient deficiency and plant stress. In this study, we hypothesized that the SPAD reading in lentil leaves could estimate leaf nitrogen content

    Obesity: when is specialist referral needed?

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    Obesity is a chronic progressive condition affecting 27% of the UK adult population. Obesity underlies much of primary care workload: 44% of type 2 diabetes (T2D) cases, 23% of ischaemic heart disease, and 41% of certain cancers are attributable to excess BMI.1 Worryingly, the number of adults with severe obesity, which significantly reduces life expectancy, has doubled to approximately 2.6 million over the past decade. Obesity and related illnesses lead to significant healthcare costs, estimated at £6.1 billion per year in the UK, with additional societal costs of £27 billion from reduced productivity secondary to obesity-related ill-health.

    Defining the relationship between COPD and CVD: what are the implications for clinical practice?

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    Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their presence is associated with increased risk for hospitalization, longer length of stay and all-cause and CVD-related mortality. The economic burden associated with CVD in this population is considerable and the cumulative cost of treating comorbidities may even exceed that of treating COPD itself. Our understanding of the biological mechanisms that link COPD and various forms of CVD has improved significantly over the past decade. But despite broad acceptance of the prognostic significance of CVDs in COPD, there remains widespread under-recognition and undertreatment of comorbid CVD in this population. The reasons for this are unclear; however institutional barriers and a lack of evidence-based guidelines for the management of CVD in people with COPD may be contributory factors. In this review, we summarize current knowledge relating to the prevalence and incidence of CVD in people with COPD and the mechanisms that underlie their coexistence. We discuss the implications for clinical practice and highlight opportunities for improved prevention and treatment of CVD in people with COPD. While we advocate more active assessment for signs of cardiovascular conditions across all age groups and all stages of COPD severity, we suggest targeting those aged under 65 years. Evidence indicates that the increased risks for CVD are particularly pronounced in COPD patients in mid-to-late-middle-age and thus it is in this age group that the benefits of early intervention may prove to be the most effective

    Potential mechanisms underlying the effect of bariatric surgery on eating behaviour

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    PURPOSE OF REVIEW: Reduced energy intake, resulting from favourable changes in eating behaviour, is the predominant driver of weight loss following bariatric surgery. Here we review the most recent studies examining the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy, the two most common bariatric procedures, upon eating behaviour and the suggested underlying biological mechanisms. RECENT FINDINGS: Following RYGB or sleeve gastrectomy, most people report subjective changes in appetite, taste and food preference, with decreased high-fat preference most commonly reported. Objective postsurgery changes in taste and olfactory acuity occur. A new phenomenon, 'meal-size aversion', may contribute to reduced postoperative energy intake. Recent studies provide evidence for peptide YY3-36, glucagon-like peptide-1, ghrelin, neurotensin and oleoylethanolamide as mediators of postoperative eating behaviour changes. Factors modulating these changes include sex, type 2 diabetes status, genetics and bariatric procedure. New studies implicate central dopaminergic and opioid receptor signalling as key neural mediators driving altered eating behaviour. Brain neuroimaging studies show that obesity-associated changes in food-cue responses, brain connectivity and structural abnormalities are normalized following bariatric surgery. SUMMARY: Understanding the biological mechanisms mediating the eating behaviour changes engendered by bariatric surgery may lead to the development of novel therapeutic strategies for people with obesity

    Gastric Fistula in the Chest After Sleeve Gastrectomy: a Systematic Review of Diagnostic and Treatment Options

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    This study aimed to establish the optimal diagnostic and treatment algorithm for the management of gastric fistula in the chest (GFIC) after sleeve gastrectomy (SG) through a systematic review of published cases. A multi-database search was performed, which produced 1182 results, of which 26 studies were included in this systematic review. The initial presentation included subphrenic collections, leaks, or (recurrent) pneumonia with associated symptoms such as persistent cough, fever, and/or dyspnea. Computed tomography (CT) scan in combination with either upper gastrointestinal (UGI) series or an esophagogastroduodenoscopy (EGD) was used to adequately diagnose the fistulas. Initial treatment was either with clips and/or clips and stents that were placed endoscopically. When unsuccessful in the majority of the cases, the surgical treatment consisted of total gastrectomy and Roux-en-Y esophagojejunostomy in a laparoscopic or open fashion

    Existing and new arrangements of pumped-hydro storage plants

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    The energy sector is undergoing substantial transition with the integration of variable renewable energy sources, such as wind and solar energy. These sources come with hourly, daily, seasonal and yearly variations; raising the need for short and long-term energy storage technologies to guarantee the smooth and secure supply of electricity. This paper critically reviews the existing types of pumped-hydro storage plants, highlighting the advantages and disadvantages of each configuration. We propose some innovative arrangements for pumped-hydro storage, which increases the possibility to find suitable locations for building large-scale reservoirs for long-term energy and water storage. Some of the proposed arrangements are compared in a case study for the upper Zambezi water basin, which has considerable water storage limitations due to its flat topography and arid climate. Results demonstrate that the proposed combined short and long-term cycles pumped-storage arrangement could be a viable solution for energy storage and reduce the cost for water storage to near zero
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