3 research outputs found
Supplement study update for Reach Out: a multi-arm randomized trial of behavioral interventions for hypertension initiated in the emergency department: Reach Out Cognition
Abstract
Background
Reach Out is a factorial trial studying multicomponent behavioral interventions to reduce blood pressure in hypertensive emergency department patients. The original study protocol was published in June 2020. Here, we describe the updated protocol, including a supplemental study, Reach Out Cognition. Reach Out Cognition is a remote study that will assess the acceptability, feasibility, and satisfaction of digital, self-administered cognitive assessments and Bluetooth-enabled, self-measured blood pressure monitoring in the Reach Out population. We will also estimate the prevalence of mild cognitive impairment in Reach Out participants.
Methods
Reach Out Cognition includes remote enrollment and follow-up assessments. Reach Out Cognition extends Reach Out data collection past the current 12âmonths to 15 and 18âmonths. Participants will be Reach Out participants who complete their 12-month outcome assessments and opt to continue in the cohort study. Participants will continue to receive the Reach Out intervention, consisting of (1) daily healthy behavior text messaging and (2) weekly self-measured blood pressure monitoring. Blood pressure will be measured using Bluetooth-enabled self-measured blood pressure monitoring devices, and cognition will be measured using digital self-administered cognitive assessments at 12, 15, and 18âmonths.
Discussion
Reach Out Cognition will explore the potential of remote, digital, self-administered assessments of blood pressure and cognition among predominantly working-age Black Americans. Reach Out Cognition will inform future clinical trials and clinical remote monitoring of blood pressure and cognition that may lead to new approaches to treating and reducing hypertension and cognitive disparities.
Trial registration
ClinicalTrials.gov
NCT03422718. The record was first available to the public on January 30, 2018, prior to the enrollment of patients on March 25, 2019.http://deepblue.lib.umich.edu/bitstream/2027.42/173821/1/13063_2021_Article_5806.pd
A Physical Activity and Diet JustâinâTime Adaptive Intervention to Reduce Blood Pressure: The myBPmyLife Study Rationale and Design
Background Smartphone applications and wearable devices are promising mobile health interventions for hypertension selfâmanagement. However, most mobile health interventions fail to use contextual data, potentially diminishing their impact. The myBPmyLife Study is a justâinâtime adaptive intervention designed to promote personalized selfâmanagement for patients with hypertension. Methods and Results The study is a 6âmonth prospective, randomizedâcontrolled, remotely administered trial. Participants were recruited from the University of Michigan Health in Ann Arbor, Michigan or the Hamilton Community Health Network, a federally qualified health center network in Flint, Michigan. Participants were randomized to a mobile application with a justâinâtime adaptive intervention promoting physical activity and lowerâsodium food choices as well as weekly goal setting or usual care. The mobile study application encourages goal attainment through a central visualization displaying participants' progress toward their goals for physical activity and lowerâsodium food choices. Participants in both groups are followed for up for 6âmonths with a primary end point of change in systolic blood pressure. Exploratory analyses will examine the impact of notifications on step count and selfâreported lowerâsodium food choices. The study launched on December 9, 2021, with 484 participants enrolled as of March 31, 2023. Enrollment of participants was completed on July 3, 2023. After 6âmonths of followâup, it is expected that results will be available in the spring of 2024. Conclusions The myBPmyLife study is an innovative mobile health trial designed to evaluate the effects of a justâinâtime adaptive intervention focused on improving physical activity and dietary sodium intake on blood pressure in diverse patients with hypertension. Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT05154929