A Review - Colorectal Cancer, Prevalence, along with Screening, Diagnosis, and Novel Therapies

Colorectal cancer is considering a communal health problem and in the whole world, its number is third in all cancers that were diagnosed. It causes a significant burden in terms of sickness and death with the estimation of seven lakhs annual deaths. In many countries of the world western way of life is rapidly adopted that is a well-debated factor for colorectal cancer and in term of primary preventive measures, it could be besieged. Comparatively slow advancement of this cancer allows severe reduction of occurrence and death rate with the help of secondary prevention. These facts motivate primary care physicians to play a key role in health plans that improve prevention and rapid diagnosis. In ancient years, the targeted therapies with combinational treatment have proven to be very effective for specific colorectal cancer patients. These therapies are epidermal growth factor, receptor inhibitor, and growth factor. As the advancements in clinic and science have visible that give new treatment options for metastatic colorectal cancer, the five-year existence rate is still fourteen percent low. But in other subtypes of colorectal cancer, the results may not be successful and not highly explored. We can reduce side effects and make the treatment effect by using alternative therapies instead of traditional therapies such as anticancer drugs, probiotics, etc. Herein, some major topics related to CRC in recent literature have been reviewed, to acknowledge its malignancy, risk, and defensive factors, along with the screening methodologies. Moreover, we also debate over preventive as well as screening strategies to fight against CRC