The significance of connective tissue dysplasia in the development of cervical incompetence

100 pregnancy women at 16-24 weeks gestations were examined to study significance of connective tissue dysplasia in the development of cervical incompetence. Data of objective examination, anamnesis, physical examination. The role of connective tis-sue dysplasia was firmed by presence its markers, loss of weight, diseases with connective tissue dysplasia.Значение дисплазии соединительной ткани в развитии истмико-цервикальной недостаточности изучено у 100 беременных на сроке 16-24 недель. Исследовали анамнез, данные объективного осмотра и физикального обследования. Значение дисплазии соединительной ткани подтверждено наличием стигм и заболеваний с дисплазией соединительной ткани

A Two-Dimensional Hydrostatically Equilibrium Atmosphere of a Neutron Star with Given Differential Rotation

An analytic solution has been found in the Roche approximation for the axially symmetric structure of a hydrostatically equilibrium atmosphere of a neutron star produced by collapse. A hydrodynamic (quasione-dimensional) model for the collapse of a rotating iron core in a massive star gives rise to a heterogeneous rotating protoneutron star with an extended atmosphere composed of matter from the outer part of the iron core with differential rotation (Imshennik and Nadyozhin, 1992). The equation of state of a completely degenerate iron gas with an arbitrary degree of relativity is taken for the atmospheric matter. We construct a family of toroidal model atmospheres with total masses $M \approx 0.1 \div 0.2 M_{\odot}$ and total angular momenta $J \approx (1 \div 5.5) \cdot 10^{49} erg \cdot s$, which are acceptable for the outer part of the collapsed iron core, in accordance with the hydrodynamic model, as a function of constant parameters $\omega_{0} and r_{0}$ of the specified differential rotation law $\Omega = \omega_{0}\exp{\Big[-\frac{(r\sin{\Theta})^{2}}{r_{0}^{2}}\Big]}$ in spherical coordinates. The assumed rotation law is also qualitatively consistent with the hydrodynamic model for the collapse of an iron core.Comment: 9 pages, 6 figures, 1 tabl

The role of system dysplasia in pregnancy complications and mature

An article presents the review of reasons and clinical of system dysplasia in pregnancy and its complicationsВ статье приводится обзор литературы, посвящённый причинам возникновения, клиническим проявлениям дисплазии соединительной ткани и её влияние на исход беременности и родов

A hydrodynamic model for asymmetric explosions of rapidly rotating collapsing supernovae with a toroidal atmosphere

We numerically solved the two-dimensional axisymmetric hydrodynamic problem of the explosion of a low-mass neutron star in a circular orbit. In the initial conditions, we assumed a nonuniform density distribution in the space surrounding the collapsed iron core in the form of a stationary toroidal atmosphere that was previously predicted analytically and computed numerically. The configuration of the exploded neutron star itself was modeled by a torus with a circular cross section whose central line almost coincided with its circular orbit. Using an equation of state for the stellar matter and the toroidal atmosphere in which the nuclear statistical equilibrium conditions were satisfied, we performed a series of numerical calculations that showed the propagation of a strong divergent shock wave with a total energy of 0.2x10^51 erg at initial explosion energy release of 1.0x10^51 erg. In our calculations, we rigorously took into account the gravitational interaction, including the attraction from a higher-mass (1.9M_solar) neutron star located at the coordinate origin, in accordance with the rotational explosion mechanism for collapsing supernovae.W e compared in detail our results with previous similar results of asymmetric supernova explosion simulations and concluded that we found a lower limit for the total explosion energy.Comment: 13 pages, 5 figures, 2 table

Comparative assessment of the results of open-, laparoscopic-, and laparoscopically assisted radical nephrectomies

Objectives. To compare the results of traditional open-, laparoscopic-, and laparoscopically assisted radical nephrectomies in the treatment of patients with renal cancer. One of the goals was to define the roll of laparoscopic operations and their advantages over open procedures.Subjects and methods. Seventy-four patients with renal cancer age of 36 to 79 years (mean age 58/7 years) were divided into 3 groups: 1) open radical nephrectomy (n = 32); 2) radical nephrectomy via laparoscopic transabdominal access (n = 17); and 3) radical nephrectomy via laparoscopically assisted access (n = 25). All the patient groups were comparable with regard to the T stage and the size of a tumor.Results. In the open nephrectomy group mean duration of surgery was 152 min; mean blood loss — 264 ml; mean hospital stay — 15.8 days; early postoperative complications were not observed. In the laparoscopic transabdominal surgery, these were 117 min, 138 ml, and 7.5, respectively; early postoperative complications were also absent. In laparoscopically assisted transabdominal access, the duration of an operation was 80 to 300 min (at the stage of procedure mastering) and averaged 123.1 min; blood loss was 50 to 700 ml (mean 228.5 ml). There were no intraoperative complications. The average postoperative hospital stay — 9.4 days.Conclusion. The results of open- and laparoscopic-access nephrectomies are comparable in the duration of an operation, the volume of blood loss, and the presence of intraoperative complications. The parameters of the early and late postoperative periods are also identical. Recovery is shorter when endovideo-assisted interventions are applied

The structure of hereditary diseases in children hospitalized in a specialized clinic

Purpose: to analyze the structure of hereditary pathology and the results of genetic studies in children in a specialized clinic.Results.1045 children from 79 regions of the Russian Federation were examined and treated in the pediatric department of congenital and hereditary diseases in 2018. There were 25% of patients from Moscow and Moscow region and 75% from other territories. After examination all patients were divided into 2 large cohorts: patients with hereditary diseases diagnosed by clinical and laboratory data (737 children; 70%) and patients with undifferentiated pathological conditions with unclear genesis at the time of discharge from the hospital (308 children; 30%). In the cohort of hereditary diseases there were the most numerous (about 100 children in each) groups of patients with Ehlers–Danlos syndrome, imperfect osteogenesis and rare heterogeneous genetic syndromes. The groups of rickets- like diseases, chromosomal syndromes and Rett syndrome included 50-70 patients. Other groups were smaller. Half of the hospitalized patients required genetic analysis. The highest percentage of molecular genetically / cytogenetically confirmed diagnoses was found in the groups of chromosomal diseases, rare genetic syndromes of lysosomal and mitochondrial diseases, Rett syndrome, and aminoacidopathy. It is worth mentioning that a primary diagnosis was not established during a genetic study in 57 children (18%) children from the general cohort of patients with hereditary diseases, so the researchers used other methods of analysis or bioinformatic revision of the results.Conclusion: The authors found a large variety of genetic diseases in children requiring examination and treatment in a specialized hospital. 1/5 of the examined children require additional genetic testing or repeated bioinformatic interpretation of the data