Landau Transport equations in slave-boson mean-field theory of t-J model

In this paper we generalize slave-boson mean-field theory for $t-J$ model to the time-dependent regime, and derive transport equations for $t-J$ model, both in the normal and superconducting states. By eliminating the boson and constraint fields exactly in the equations of motion we obtain a set of transport equations for fermions which have the same form as Landau transport equations for normal Fermi liquid and Fermi liquid superconductor, respectively with all Landau parameters explicity given. Our theory can be viewed as a refined version of U(1) Gauge theory where all lattice effects are retained and strong correlation effects are reflected as strong Fermi-liquid interactions in the transport equation. Some experimental consequences are discussed.Comment: 19 page

Proteomic analysis of heat treated bitter gourd (Momordica charantia L. var. Hong Kong Green) using 2D-DIGE

This study aimed to investigate the changes in the proteome of bitter gourd prior to and after subjecting to boiling and microwaving. A comparative analysis of the proteome profiles of raw and thermally treated bitter gourds was performed using 2D-DIGE. The protein content and number of protein spots in raw sample was higher when compared to the cooked samples. Qualitative analysis revealed that 103 (boiled sample) and 110 (microwaved sample) protein spots were up regulated whereas 120 (boiled sample) and 107 (microwaved sample) protein spots were down regulated. Ten protein spots with the highest significant fold change in the cooked samples were involved in carbohydrate/energy metabolisms and stress responses. Small heat shock proteins, superoxide dismutase, quinone oxidoreductase, UDP-glucose pyrophosphorylase and phosphoglycerate kinase play a role in heat-stress-mediated protection of bitter gourd. This study suggests that appropriate heat treatment (cooking methods) can lead to induction of selected proteins in bitter gourd

Customized cooking method improves total antioxidant activity in selected vegetables

The present study compares water-soluble phenolic content (WPC) and antioxidant activities in Chinese long bean (Vigna unguiculata), bitter gourd (Momordica charantia), water convolvulus (Ipomoea aquatica) and broccoli (Brassica olearacea) prior to and after subjecting to boiling, microwaving and pressure cooking. The total antioxidant activity was increased in cooked water convolvulus, broccoli and bitter gourd, estimated based on the ferric reducing antioxidant power, the Trolox equivalent antioxidant capacity and 2,2-diphenyl-1-picryl-hydrazyl radical scavenging activity. Pressure cooking did not cause any significant decline in the antioxidant property. Boiling generally improved the overall antioxidant activity in all the vegetables. Correlation analysis suggests that WPC contributed to significant antioxidant activities in these vegetables. Thus, prudence in selecting an appropriate cooking method for different vegetables may improve or preserve their nutritional value

Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy

Background: Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with diabetic retinopathy (DR). However, the mechanism on how it affects the disease development is still unclear. Aim: This study aims to investigate the relationship between 2245G/A RAGE gene polymorphism and selected pro-inflammatory, oxidative-glycation markers in DR patients. Methods: A total of 371 unrelated type 2 diabetic patients 200 with retinopathy, 171 without retinopathy (DNR) and 235 healthy subjects were recruited. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism method followed by DNA sequencing. The nuclear and cytosolic extracts from peripheral blood mononuclear cells were used for nuclear factor kappa B (NF-kappa B) p65 and superoxide dismutase activity measurement respectively. Plasma was used for glutathione peroxidase activity, advanced oxidation protein product (AOPP), monocyte chemoattractant protein (MCP)-1, pentosidine and soluble RAGE (sRAGE) measurements. Results: DR patients with 2245GA genotype had significantly elevated levels of activated NF-kappa B p65, plasma MCP-1, AOPP and pentosidine but lower level of sRAGE when compared to DR patients with wild-type 2245GG. Conclusion: The RAGE gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and circulating sRAGE in DR patients. Patients with 2245GA RAGE genotype could aggravate DR possibly via NF-kappa B mediated inflammatory pathway. (C) 2013 Elsevier B.V. All rights reserved

Raman characterization of germanium nanocrystals in amorphous silicon oxide films synthesized by rapid thermal annealing

Journal of Applied Physics8631398-1403JAPI

Association analysis of-429T/C and-374T/A polymorphisms of receptor of advanced glycation end products (RAGE) gene in Malaysian with type 2 diabetic retinopathy

Conflicting results have been reported in different populations on the association between two particular RAGE gene polymorphisms (-429T/C and -374T/A) and retinopathy in diabetic patients. Therefore this study was designed to assess the association between both gene polymorphisms with retinopathy in Malaysian diabetic patients. A total of 342 type 2 diabetic patients 171 without retinopathy (DNR) and 171 with retinopathy (DR) and 235 healthy controls were included in this study. Genomic DNA was obtained from blood samples and the screening for the gene polymorphisms was done using polymerase chain reaction-restriction fragment length polymorphism approach. Overall, the genotype distribution for both polymorphisms was not statistically different (p > 0.05) among the control, DNR and DR groups. The -429C minor allele frequency of DR group (12.0%) was not significantly different (p > 0.05) when compared to DNR group (16.1%) and healthy controls (11.3%). The -374A allele frequency also did not differ significantly between the control and DNR (p > 0.05), control and DR (p > 0.05) as well as DNR and DR groups (p > 0.05). This is the first study report on RAGE gene polymorphism in Malaysian DR patients. In conclusion, -429T/C and -374T/A polymorphisms in the promoter region of RAGE gene were not associated with Malaysian type 2 DR patients. (C) 2011 Elsevier Ireland Ltd. All rights reserved

DNA strand breaks and poly (ADP-ribose) polymerase activation induced by crystalline nickel subsulfide in MRC-5 lung fibroblast cells

Human and Experimental Toxicology1511891-897HETO

Investigation of SLC2A1 26177A/G gene polymorphism via high resolution melting curve analysis in Malaysian patients with diabetic retinopathy

Purpose In this study, we aimed to investigate the possible association between SLC2A126177A/Gpolymorphism and diabetic retinopathy (DR) in Malaysianpatients with type 2 diabetes. Methods Genomic DNA was extracted from 211 Malaysian type 2 diabeticpatients (100 without retinopathy DNR, 111 with retinopathy) and 165 healthy controls. A highresolutionmelting assay developed in this study was used to detect SLC2A126177A/Gpolymorphism followed by statistical analysis. Results A statistically significant difference in 26177 G minor allele frequency between healthy controls (19.7 %) and total patient group (26.1 %) (p 0.05). Conclusions This is the first study which shows that SLC2A1 26177G allele is associated with type 2 diabetes in Malaysian population but not with DR

Patients' and healthcare professionals' perspectives towards technology-assisted diabetes self-management education. A qualitative systematic review

10.1371/journal.pone.0237647PLoS ONE158-Auge023764

A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth

10.1186/s13287-020-01899-xStem Cell Research and Therapy11139