Hyperbilirubinemia due to minor blood group (anti-E) incompatibility in a newborn: A case report

In addition to Rh and ABO incompatibilities subgroup incompatibilities may rarely play a role among the causes of hemolytic anemia and indirect hyperbilirubinemia in newborns. The most common minor blood group antigens that cause blood incompatibility between the mother and baby are C, c, E, e, Kell, Duffy, Diego, Kidd and MNSs antigens. In this article, a newborn in whom hyperbilirubinemia due to anti-E minor blood group incompatibility developed and was treated with phototherapy succesfully is presented and minor blood group incompatibilities due to anti-E are reviewed

Human metapneumovirus pneumonia: case report

İlk kez 2001’de tanımlanan human metapnömovirüs (hMPV), 10 yaş altı çocuklarda üst ve alt solunum yolu enfeksiyonlarında izole edilebilen bir virus olsa da ülkemizde bu virusla ilgili olarak yayınlanmış fazla sayıda çalışmaya rastlanmamıştır. Human metapneumovirus tanısında altın standart yöntem RT-PCR yöntemidir. Pnömoni kliniği ve laboratuvar bulguları ile başvuran hastalarda viral/bakteriyel pnömoni ayırıcı tanısında PCR gibi ileri tanı yöntemlerinin hızlı ve etkili bir şekilde kullanılması, hastalara gereksiz antibiyotik tedavisi uygulanmasının önüne geçilmesi ve gerekli durumlarda uygun antiviral tedavinin verilebilmesi açısından önemli katkı sağlayacaktır. Bu makalede solunum sıkıntısı bulguları ve oksijen gereksinimi ile başvuran ve enfeksiyon etkeninin human metapneumovirus olarak tespit edildiği 18 aylık hasta sunulmuş ve 2 yaş altı çocuklarda solunum yolu enfeksiyonlarında klasik solunum yolu viruslarına göre çok daha ender rastlanan ve son yıllarda tanımlanmış bir virus olan human metapnömovirüs ile etken olarak karşılaşılabileceği vurgulanmak istenmiştir

Association between early idiopathic neonatal jaundice and urinary tract infections

Background and purpose: Etiologic role, incidence, demographic, and response-to-treatment characteristics of urinary tract infection (UTI) among neonates, its relationship with significant neonatal hyperbilirubinemia, and abnormalities of the urinary system were studied in a prospective investigation in early (<= 10 days) idiopathic neonatal jaundice in which all other etiologic factors of neonatal hyperbilirubinemia were ruled out. Patients and methods: Urine samples for microscopic and bacteriologic examination were obtained with bladder catheterization from 155 newborns with early neonatal jaundice. Newborns with a negative urine culture and with a positive urine culture were defined as group I and group II, respectively, and the 2 groups were compared with each other. Results: The incidence of UTI in whole of the study group was 16.7%. Serum total and direct bilirubin levels were statistically significantly higher in group II when compared with group I (P = .005 and P = .001, respectively). Decrease in serum total bilirubin level at the 24th hour of phototherapy was statistically significantly higher in group I compared with group II (P =.022). Conclusions: Urinary tract infection should be investigated in the etiologic evaluation of newborns with significant hyperbilirubinemia. The possibility of UTI should be considered in jaundiced newborns who do not respond to phototherapy well or have a prolonged duration of phototherapy treatment