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Π¨ΠΈΡΠΎΠΊΠΎΠ΅ ΠΌΠ½ΠΎΠ³ΠΎΠΎΠ±ΡΠ°Π·ΠΈΠ΅ ΠΊΠ΅ΡΠ°ΡΠΈΠ½ΠΎΠ² ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°
Π review presents systematic data about the diversity of human keratins. The results of numerous studies concerning the structure and functions of keratins, their distribution in various cells and tissues were summarized. The role of these proteins in the development of human hereditary diseases, as well as modern approaches in use keratins in immunohistochemistry and perspectives of their further studies are discussed.ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠΈΡΡΠ΅ΠΌΠ°ΡΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΎ ΡΠ°Π·Π½ΠΎΠΎΠ±ΡΠ°Π·ΠΈΠΈ ΠΊΠ΅ΡΠ°ΡΠΈΠ½ΠΎΠ² ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°. ΠΠ±ΠΎΠ±ΡΠ΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΌΠ½ΠΎΠ³ΠΎΡΠΈΡΠ»Π΅Π½Π½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π² ΠΎΠ±Π»Π°ΡΡΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΡΡΡΡΠΊΡΡΡΡ ΠΈ ΡΡΠ½ΠΊΡΠΈΠΉ ΠΊΠ΅ΡΠ°ΡΠΈΠ½ΠΎΠ², ΠΈΡ
ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΠΊΠ»Π΅ΡΠΊΠ°Ρ
ΠΈ ΡΠΊΠ°Π½ΡΡ
ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ°. ΠΠ±ΡΡΠΆΠ΄Π°ΡΡΡΡ ΡΠΎΠ»Ρ Π΄Π°Π½Π½ΡΡ
Π±Π΅Π»ΠΊΠΎΠ² Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ Π½Π°ΡΠ»Π΅Π΄ΡΡΠ²Π΅Π½Π½ΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠ΅ΡΠ°ΡΠΈΠ½ΠΎΠ² Π² ΠΈΠΌΠΌΡΠ½ΠΎΠ³ΠΈΡΡΠΎΡ
ΠΈΠΌΠΈΠΈ ΠΈ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Ρ ΠΈΡ
Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠΈΡ
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