Some majorization inequalities in multivariate analysis and their applications

Final report has title: Some majorization inequalities in multivariate analysis and their applicationsIssued as Progress reports [nos. 1-2], and Final report, Project no. G-37-63

Inequalities in multivariate analysis and reliability theory

Issued as Progress report, and Final report, Project no. G-37-63

The Submillimeter Array

The Submillimeter Array (SMA), a collaborative project of the Smithsonian Astrophysical Observatory (SAO) and the Academia Sinica Institute of Astronomy and Astrophysics (ASIAA), has begun operation on Mauna Kea in Hawaii. A total of eight 6-m telescopes comprise the array, which will cover the frequency range of 180-900 GHz. All eight telescopes have been deployed and are operational. First scientific results utilizing the three receiver bands at 230, 345, and 690 GHz have been obtained and are presented in the accompanying papers.Comment: 10 pages, 4 figure

On Partitioning A Set of Normal Populations by Their Locations with Respect to a Control Using a Single-stage, a Two-stage and a Sequential Procedure

1 online resource (PDF, 61 pages

Analysis and Design of Roof Turbine Ventilator for Wind Energy Harvest

Harvesting energy using roof turbine ventilator and electroactive material has been investigated to verify its performance. Since electric power gained from a single piece of regular size is usually small, auxiliary device to vibrate multiple pieces of electroactive materials in order to harvest more power is required. In this paper, an attempt of using the developed nozzle wind collector associated with the popular roof turbine ventilator employed with gear mechanism to impact and vibrate a group of electroactive material to generate electricity is proposed. Number of blade and blade angle of the roof turbine ventilator are influential to the effectiveness of wind collection. Also, number of electroactive material employed on the turbine ventilator under the wind speed in environment eventually determines the efficiency of wind harvest. A simple model is derived to estimate the minimum driving force from the wind power that needs to overcome the inertia of the turbine ventilator mechanism and the electromechanical energy conversion of electroactive materials. Wind drag force is calculated by using CFD is assumed to provide such driving force. Various combinations of the blade angle, number of blade and electroactive material actuators are investigated in simulations. Optimum design concerning the environment wind resource and configuration of turbine ventilator is discussed. According to several case studies, a few of design trends is addressed for better efficiency of energy harvest. Since multiple electroactive materials are employed, circuitry design with parallel input sources is implemented to sum up the current and integrate the power

Optimal Allocation of Observations for Partitioning a Set of Normal Populations in Comparison with a Control

1 online resource (PDF, 27 pages

Central Charge Anomalies in 2D Sigma Models with Twisted Mass

We discuss the central charge in supersymmetric ${\cal N}=2$ sigma models in two dimensions. The target space is a symmetric K\"ahler manifold, CP$(N-1)$ is an example. The U(1) isometries allow one to introduce twisted masses in the model. At the classical level the central charge contains Noether charges of the U(1) isometries and a topological charge which is an integral of a total derivative of the Killing potentials. At the quantum level the topological part of the central charge acquires anomalous terms. A bifermion term was found previously, using supersymmetry which relates it to the superconformal anomaly. We present a direct calculation of this term using a number of regularizations. We derive, for the first time, the bosonic part in the central charge anomaly. We construct the supermultiplet of all anomalies and present its superfield description. We also discuss a related issue of BPS solitons in the CP(1) model and present an explicit form for the curve of marginal stability.Comment: 30 pages, 1 figure, references adde

Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer

Background: Granulin-epithelin precursor (GEP), a secretory growth factor, demonstrated overexpression in various human cancers, however, mechanism remain elusive. Primary liver cancer, hepatocellular carcinoma (HCC), ranks the second in cancer-related death globally. GEP controlled growth, invasion, metastasis and chemo-resistance in liver cancer. Noted that GEP gene locates at 17q21 and the region has been frequently reported to be amplified in subset of HCC. The study aims to investigate if copy number gain would associate with GEP overexpression. Methods: Quantitative Microsatellite Analysis (QuMA) was used to quantify the GEP DNA copy number, and fluorescent in situ hybridization (FISH) was performed to consolidate the amplification status. GEP gene copy number, mRNA expression level and clinico-pathological features were analyzed. Results: GEP DNA copy number determined by QuMA corroborated well with the FISH data, and the gene copy number correlated with the expression levels (n = 60, r = 0.331, P = 0.010). Gain of GEP copy number was observed in 20% (12/60) HCC and associated with hepatitis B virus infection status (P = 0.015). In HCC with increased GEP copy number, tight association between GEP DNA and mRNA levels were observed (n = 12, r = 0.664, P = 0.019). Conclusions: Gain of the GEP gene copy number was observed in 20% HCC and the frequency comparable to literatures reported on the chromosome region 17q. Increased gene copy number contributed to GEP overexpression in subset of HCC. © Yung et al; licensee BioMed Central.published_or_final_versio

Optimising antimicrobial prescription in hospitals by introducing an antimicrobial stewardship programme in Hong Kong: Consensus statement

Objective. To discuss the implementation of an 'antimicrobial stewardship programme' as a means to improve the quality of antimicrobial use in a hospital setting in Hong Kong. Participants. Consensus working group on 'antimicrobial stewardship programme', The Scientific Committee on Infection Control, Centre for Health Protection, Department of Health, comprised 11 experts. The remit of the working group was to discuss the rationale and requirement for optimising antimicrobial prescriptions in hospitals by the introduction of an 'antimicrobial stewardship programme'. Evidence. PubMed articles, national and international guidelines, and abstracts of international meetings published between January 2000 and December 2004 on programmes for improving the use of antimicrobials in hospitals. Only English medical literature was reviewed. Consensus process. Data search was performed independently by three members of the working group. They met on three occasions before the meeting to discuss all collected articles. A final draft was circulated to the working group before a meeting on 3 January 2005. Five commonly asked questions about an 'antimicrobial stewardship programme' were selected for discussion by the participants. Published information on the rationale, components, outcome measures, advantages, and disadvantages of the programme was reviewed. Recent unpublished data from local studies of an 'antimicrobial stewardship programme' were also discussed. The timing, potential problems, and practical issues involved in the implementation of an 'antimicrobial stewardship programme' in Hong Kong were then considered. The consensus statement was circulated to and approved by all participants. Conclusion. The continuous indiscriminate and excessive use of antimicrobial agents promotes the emergence of antibiotic-resistant organisms. Antimicrobial resistance substantially raises already-rising health care costs and increases patient morbidity and mortality. Pattern of prescriptions in hospitals can be improved through the implementation of an 'antimicrobial stewardship programme'. A 'universal' and 'continuous' 'antimicrobial stewardship programme' should now be established in Hong Kong hospitals.published_or_final_versio