516 research outputs found

    Effect of dielectric thin films on reflection properties of metal hole arrays

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    This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in APPLIED PHYSICS LETTERS. 96(2):021106 (2010) and may be found at https://doi.org/10.1063/1.3292024 .We study the effect of a dielectric film attached to the surface of a metal hole array (MHA) on the reflection spectrum in the terahertz (THz) region. The frequency of the reflection dip, attributed to the excitation of surface waves in the vicinity of the MHA surface, shifts to lower frequencies with increasing dielectric film thickness. This resonant characteristic of MHAs can be applied to highly sensitive THz sensing for samples attached to the MHA surface. We also investigate the dependence of the reflection spectrum on the MHA's thickness and the side to which the dielectric film is attached.ArticleAPPLIED PHYSICS LETTERS. 96(2):021106 (2010)journal articl

    Autism-related traits are related to effectiveness of immersive visual guidance on spatial cognitive ability: a pilot study

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    A head-mounted display could potentially restrict users’ visual fields and thereby impair their spatial cognitive ability. Spatial cognition can be assisted with immersive visual guidance. However, whether this technique is useful for individuals with autism-spectrum disorder (ASD) remains unclear. Given the recent virtual reality (VR) contents targeting individuals with ASD, the relationship between ASD-related traits and the effectiveness of immersive visual guidance should be clarified. This pilot study evaluated how ASD-related traits (autistic traits and empathizing–systemizing cognitive styles) among typically developing individuals are related to the effectiveness of visual guidance. Participants performed visual search and spatial localization tasks while using immersive visual guidance. In the visual search task, participants searched immersive VR environments for a target object and pushed a button according to the target color as quickly as possible. In the localization task, they viewed immersive visual guidance for a short duration and localized the guided direction via a controller. Results showed that visual search times were hastened with systemizing cognition. However, ASD-related traits were not significantly related to localization accuracy. These findings suggest that immersive visual guidance is generally useful for individuals with higher ASD-related traits

    Microglia-triggered hypoexcitability plasticity of pyramidal neurons in the rat medial prefrontal cortex

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    細菌感染で脳機能が変化する仕組みを解明 --ミクログリアは大脳の神経活動を低下させる--. 京都大学プレスリリース. 2022-02-17.Lipopolysaccharide (LPS), an outer component of Gram-negative bacteria, induces a strong response of innate immunity via microglia, which triggers a modulation of the intrinsic excitability of neurons. However, it is unclear whether the modulation of neurophysiological properties is similar among neurons. Here, we found the hypoexcitability of layer 5 (L5) pyramidal neurons after exposure to LPS in the medial prefrontal cortex (mPFC) of juvenile rats. We recorded the firing frequency of L5 pyramidal neurons long-lastingly under in vitro whole-cell patch-clamp, and we found a reduction of the firing frequency after applying LPS. A decrease in the intrinsic excitability against LPS-exposure was also found in L2/3 pyramidal neurons but not in fast-spiking interneurons. The decrease in the excitability by immune-activation was underlain by increased activity of small-conductance Ca²⁺-activated K⁺ channels (SK channels) in the pyramidal neurons and tumor necrosis factor (TNF)-α released from microglia. We revealed that the reduction of the firing frequency of L5 pyramidal neurons was dependent on intraneuronal Ca²⁺ and PP2B. These results suggest the hypoexcitability of pyramidal neurons caused by the upregulation of SK channels via Ca²⁺-dependent phosphatase during acute inflammation in the mPFC. Such a mechanism is in contrast to that of cerebellar Purkinje cells, in which immune activation induces hyperexcitability via downregulation of SK channels. Further, a decrease in the frequency of spontaneous inhibitory synaptic transmission reflected network hypoactivity. Therefore, our results suggest that the directionality of the intrinsic plasticity by microglia is not consistent, depending on the brain region and the cell type

    Multiphase Gas Nature in the Sub-parsec Region of the Active Galactic Nuclei I: Dynamical Structures of Dusty and Dust-free Outflow

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    We investigated dusty and dust-free gas dynamics for a radiation-driven sub-pc scale outflow in an active galactic nucleus (AGN) associated with a supermassive black hole 107M10^7 M_\odot and bolometric luminosity 104410^{44} erg s1^{-1} based on the two-dimensional radiation-hydrodynamic simulations. A radiation-driven ``lotus-like'' multi-shell outflow is launched from the inner part (r0.04r \lesssim 0.04 pc) of the geometrically thin disk, and it repeatedly and steadily produces shocks as mass accretion continues through the disk to the center. The shape of the dust sublimation radius is not spherical and depends on the angle (θ\theta) from the disk plane, reflecting the non-spherical radiation field and nonuniform dust-free gas. Moreover, we found that the sublimation radius of θ20\theta \sim 20-6060 deg varies on a timescale of several years. The ``inflow-induced outflow" contributes the obscuration of the nucleus in the sub-parsec region. The column density of the dust-free gas is NH1022N_{\rm H} \gtrsim 10^{22} cm2^{-2} for r0.04r \lesssim 0.04 pc. Gases near the disk plane (θ30\theta \lesssim 30 degree) can be the origin of the Compton-thick component, which was suggested by the recent X-ray observations of AGNs. The dusty outflow from the sub-parsec region can be also a source of material for the radiation-driven fountain for a larger scale.Comment: 13 pages, 9 figures, accepted for publication in Ap

    Sequential optimal selection of a single-qubit gate and its relation to barren plateau in parameterized quantum circuits

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    We propose an algorithm for variational quantum algorithms (VQAs) to optimize the structure of parameterized quantum circuits (PQCs) efficiently. The algorithm optimizes the PQC structure on-the-fly in VQA by sequentially replacing a single-qubit gate with the optimal one to minimize the objective function. To directly find the optimal gate, our method uses the factorization of matrices whose elements are evaluated on a set of the slightly-modified circuits. The matrix factorization enables us to not only unify the existing sequential methods for further extension but also provide rigorous proofs of their limitation and potential in comparison with conventional gradient-based optimizers. Firstly, when the circuits are sufficiently deep, the sequential methods encounter a barren plateau that the spectrum of the matrix concentrates on a single value exponentially fast with respect to the number of qubits. Secondly, if the objective functions are local observables, they can avoid barren plateaus as long as the depth of the n-qubit PQCs is O(logn)O(\log{n}). Although the family of these optimizers does not directly employ gradients of the objective function, our results establish their connection with conventional optimizations providing a consistent picture of the barren plateau. We also perform numerical experiments showing the advantages over conventional VQAs and confirm the successful optimization getting over the barren plateau in the ground state problem of the mixed field Ising model up to 12 qubits.Comment: 25 pages, 9 figure
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