A Chandra Observation of M51: Active Nucleus and Nuclear Outflows

We present a Chandra ACIS-S observation of the nuclear region of the nearby spiral galaxy M51 (NGC 5194), which has a low-luminosity Seyfert 2 nucleus. The X-ray image shows the nucleus, southern extranuclear cloud, and northern loop, the morphology of the extended emission being very similar to those seen in radio continuum and optical emission line images. The X-ray spectrum of the nucleus is well represented by a model consisting of soft thermal plasma with kT ~0.5 keV, a very hard continuum, and an Fe Kalpha emission line at 6.45 keV with an equivalent width of >2 keV. The very strong Fe line and the flat continuum indicate that the nucleus is obscured by a column density in excess of 10^24 cm^-2 and the spectrum is dominated by reflected emission from cold matter near the nucleus. The X-ray spectra of the extranuclear clouds are well fitted by a thermal plasma model with kT ~0.5 keV. This spectral shape and morphology strongly suggest that the clouds are shock heated by the bi-polar outflow from the nucleus. The shock velocities of the extranuclear cloud and northern loop inferred from the temperatures of the X-ray gas are 690 km/s and 660 km/s, respectively. By assuming a steady-state situation in which the emission of the extranuclear clouds is powered by the jets, the mechanical energy in the jets is found to be comparable to the bolometric luminosity of the nucleus.Comment: 7 pages, 5 figures, Accepted for publication in the Astrophyscal Jouna

Indigenous utilization of termite mounds and their sustainability in a rice growing village of the central plain of Laos

<p>Abstract</p> <p>Background</p> <p>The objective of this study was to investigate the indigenous utilization of termite mounds and termites in a rain-fed rice growing village in the central plain of Laos, where rice production is low and varies year-to-year, and to assess the possibility of sustainable termite mound utilization in the future. This research was carried out from 2007 to 2009.</p> <p>Methods</p> <p>The termites were collected from their mounds and surrounding areas and identified. Twenty villagers were interviewed on their use of termites and their mounds in the village. Sixty-three mounds were measured to determine their dimensions in early March, early July and middle to late November, 2009.</p> <p>Results</p> <p>Eleven species of Termitidae were recorded during the survey period. It was found that the villagers use termite mounds as fertilizer for growing rice, vegetable beds and charcoal kilns. The villagers collected termites for food and as feed for breeding fish. Over the survey period, 81% of the mounds surveyed increased in volume; however, the volume was estimated to decrease by 0.114 m³mound^-1year^-1on average due to several mounds being completely cut out.</p> <p>Conclusion</p> <p>It was concluded that current mound utilization by villagers is not sustainable. To ensure sustainable termite utilization in the future, studies should be conducted to enhance factors that promote mound restoration by termites. Furthermore, it will be necessary to improve mound conservation methods used by the villagers after changes in the soil mass of mounds in paddy fields and forests has been measured accurately. The socio-economic factors that affect mound utilization should also be studied.</p

Local instability signatures in ALMA observations of dense gas in NGC7469

We present an unprecedented measurement of the disc stability and local instability scales in the luminous infrared Seyfert 1 host, NGC7469, based on ALMA observations of dense gas tracers and with a synthesized beam of 165 x 132 pc. While we confirm that non-circular motions are not significant in redistributing the dense interstellar gas in this galaxy, we find compelling evidence that the dense gas is a suitable tracer for studying the origin of its intensely high-mass star forming ring-like structure. Our derived disc stability parameter accounts for a thick disc structure and its value falls below unity at the radii in which intense star formation is found. Furthermore, we derive the characteristic instability scale and find a striking agreement between our measured scale of ~ 180 pc, and the typical sizes of individual complexes of young and massive star clusters seen in high-resolution images.Comment: Accepted for publication in ApJ Letter

A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis

RNA synthesis inhibitors and protein synthesis inhibitors are useful for investigating whether biological events with unknown mechanisms require transcription or translation; however, the dependence of RNA synthesis has been difficult to verify because many RNA synthesis inhibitors cause adverse events that trigger a p53 response. In this study, we screened a library containing 9600 core compounds and obtained STK160830 that shows anti-apoptotic effects in irradiated wild-type-p53-bearing human T-cell leukemia MOLT-4 cells and murine thymocytes. In many of the p53-impaired cells and p53-knockdown cells tested, STK160830 did not show a remarkable anti-apoptotic effect, suggesting that the anti-apoptotic activity is p53-dependent. In the expression analysis of p53, p53-target gene products, and reference proteins by immunoblotting, STK160830 down-regulated the expression of many of the proteins examined, and the downregulation correlated strongly with its inhibitory effect on cell death. mRNA expression analyses by qPCR and nascent RNA capture kit revealed that STK160830 showed a decreased mRNA expression, which was similar to that induced by the RNA synthesis inhibitor actinomycin D but differed to some extent. Furthermore, unlike other RNA synthesis inhibitors such as actinomycin D, p53 accumulation by STK160830 alone was negligible, and a DNA melting-curve analysis showed very weak DNA-intercalating activity, indicating that STK160830 is a useful inhibitor for RNA synthesis without triggering p53-mediated damage responses

The Usefulness of Readout-Segmented Echo-Planar Imaging (RESOLVE) for Bio-phantom Imaging Using 3-Tesla Clinical MRI

Readout-segmented echo-planar imaging (RESOLVE) is a multi-shot echo-planar imaging (EPI) modality with k-space segmented in the readout direction. We investigated whether RESOLVE decreases the distortion and artifact in the phase direction and increases the signal-to-noise ratio (SNR) in phantoms image taken with 3-tesla (3T) MRI versus conventional EPI. We used a physiological saline phantom and subtraction mapping and observed that RESOLVE’s SNR was higher than EPI’s. Using RESOLVE, the combination of a special-purpose coil and a large-loop coil had a higher SNR compared to using only a head/neck coil. RESOLVE’s image distortioas less than EPI’s. We used a 120 mM polyethylene glycol phantom to examine the phase direction artifact.vThe range where the artifact appeared in the apparent diffusion coefficient (ADC) image was shorter with RESOLVE compared to EPI. We used RESOLVE to take images of a Jurkat cell bio-phantom: the cell-region ADC was 856×10−6mm2/sec and the surrounding physiological saline-region ADC was 2,951×10−6mm2/sec. The combination of RESOLVE and the 3T clinical MRI device reduced image distortion and improved SNR and the identification of accurate ADC values due to the phase direction artifact reduction. This combination is useful for obtaining accurate ADC values of bio-phantoms

AQT-D: Demonstration of the Water Resistojet Propulsion System by the ISS-Deployed CubeSat

AQT-D (AQua Thruster-Demonstrator) is a 3U CubeSat for a demonstration of a water resistojet propulsion system developed by The University of Tokyo. AQT-D installed the 1U propulsion system using water as a propellant, named AQUARIUS-1U (AQUA ResIstojet propUlsion System 1U). We completed the design and assembly of the AQT-D flight model. AQUARIUS-1U was fired on a pendulum-type thrust balance, and its performance was directly characterized in both a stand-alone test and an integrated test using an entire spacecraft system. AQT-D is currently scheduled to be delivered to JAXA in July 2019 and launched to the International Space Station (ISS) in the middle of 2019 by the H-IIB rocket. AQT-D will be deployed from the Japanese Experiment Module (JEM), known as Kibo, and demonstrate water propulsion technology