144 research outputs found
A Black-box Attack on Neural Networks Based on Swarm Evolutionary Algorithm
Neural networks play an increasingly important role in the field of machine
learning and are included in many applications in society. Unfortunately,
neural networks suffer from adversarial samples generated to attack them.
However, most of the generation approaches either assume that the attacker has
full knowledge of the neural network model or are limited by the type of
attacked model. In this paper, we propose a new approach that generates a
black-box attack to neural networks based on the swarm evolutionary algorithm.
Benefiting from the improvements in the technology and theoretical
characteristics of evolutionary algorithms, our approach has the advantages of
effectiveness, black-box attack, generality, and randomness. Our experimental
results show that both the MNIST images and the CIFAR-10 images can be
perturbed to successful generate a black-box attack with 100\% probability on
average. In addition, the proposed attack, which is successful on distilled
neural networks with almost 100\% probability, is resistant to defensive
distillation. The experimental results also indicate that the robustness of the
artificial intelligence algorithm is related to the complexity of the model and
the data set. In addition, we find that the adversarial samples to some extent
reproduce the characteristics of the sample data learned by the neural network
model
Improved High-Probability Regret for Adversarial Bandits with Time-Varying Feedback Graphs
We study high-probability regret bounds for adversarial -armed bandits
with time-varying feedback graphs over rounds. For general strongly
observable graphs, we develop an algorithm that achieves the optimal regret
with high probability, where is the independence number of the
feedback graph at round . Compared to the best existing result [Neu, 2015]
which only considers graphs with self-loops for all nodes, our result not only
holds more generally, but importantly also removes any
dependence that can be prohibitively large for applications such as contextual
bandits. Furthermore, we also develop the first algorithm that achieves the
optimal high-probability regret bound for weakly observable graphs, which even
improves the best expected regret bound of [Alon et al., 2015] by removing the
term with a refined analysis. Our algorithms are based
on the online mirror descent framework, but importantly with an innovative
combination of several techniques. Notably, while earlier works use optimistic
biased loss estimators for achieving high-probability bounds, we find it
important to use a pessimistic one for nodes without self-loop in a strongly
observable graph
Job Satisfaction Among Methadone Maintenance Treatment Clinic Service Providers in Jiangsu, China: A Cross-sectional Survey.
ObjectiveService providers' job satisfaction is critical to the stability of the work force and thereby the effectiveness of methadone maintenance treatment (MMT) programs. This study aimed to explore MMT clinic service providers' job satisfaction and associated factors in Jiangsu, China.MethodsThis secondary study used baseline data of a randomized interventional trial implemented in Jiangsu, China. A survey was conducted among 76 MMT service providers using the computer-assisted self-interview (CASI) method. Job satisfaction responses were assessed via a 30-item scale, with a higher score indicating a higher level of job satisfaction. Perceived institutional support and perceived stigma due to working with drug users were measured using a 9-item scale. Correlation and multiple linear regression analyses were performed to identify factors associated with job satisfaction.ResultsCorrelation analyses found a significant association between job satisfaction and having professional experience in the prevention and control of HIV, other sexually transmitted infections, or other infectious diseases (P = 0.046). Multiple regression analyses revealed that working at MMT clinics affiliated with Center for Disease Control and Prevention sites was associated with a lower level of job satisfaction (P = 0.014), and perception of greater institutional support (P = 0.001) was associated with a higher level of job satisfaction.ConclusionJob satisfaction among MMT clinic service providers was moderate in our study. Our findings suggest that institutional support for providers should be improved, and that acquisition of additional expertise should be encouraged
Preparation and Characterization of Solid Electrolyte Doped With Carbon Nanotubes and its Preliminary Application in NO2 Gas Sensors
In this work, a solid polymer electrolyte (SPE) doped with carbon nanotubes (CNTs) was used as a gas sensing material for a NO2 gas sensor. The electrolytes consisted of the ionic liquids (ILs) and CNTs, which were immobilized in a poly(vinylidene fluoride) (PVDF) matrix. The SPE membranes were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FTIR), and cyclic voltammetry (CV). The experimental results show that the addition of an appropriate amount of CNTs can appropriately improve the electrochemical performance of the SPE membrane. It was shown that NO2 gas sensors with an appropriate amount of CNTs added to their SPEs had a higher gas sensitivity than those with SPE containing no CNTs. When the mass ratio of PVDF, N-methyl-2-pyrrolidone (NMP), IL, and CNT was 1:4:1:0.08, the SPE showed the best gas sensitivity, and its sensitivity is 0.00275 V/ppm
OsbZIP18, a Positive Regulator of Serotonin Biosynthesis, Negatively Controls the UV-B Tolerance in Rice
Serotonin (5-hydroxytryptamine) plays an important role in many developmental processes and biotic/abiotic stress responses in plants. Although serotonin biosynthetic pathways in plants have been uncovered, knowledge of the mechanisms of serotonin accumulation is still limited, and no regulators have been identified to date. Here, we identified the basic leucine zipper transcription factor OsbZIP18 as a positive regulator of serotonin biosynthesis in rice. Overexpression of OsbZIP18 strongly induced the levels of serotonin and its early precursors (tryptophan and tryptamine), resulting in stunted growth and dark-brown phenotypes. A function analysis showed that OsbZIP18 activated serotonin biosynthesis genes (including tryptophan decarboxylase 1 (OsTDC1), tryptophan decarboxylase 3 (OsTDC3), and tryptamine 5-hydroxylase (OsT5H)) by directly binding to the ACE-containing or G-box cis-elements in their promoters. Furthermore, we demonstrated that OsbZIP18 is induced by UV-B stress, and experiments using UV-B radiation showed that transgenic plants overexpressing OsbZIP18 exhibited UV-B stress-sensitive phenotypes. Besides, exogenous serotonin significantly exacerbates UV-B stress of OsbZIP18_OE plants, suggesting that the excessive accumulation of serotonin may be responsible for the sensitivity of OsbZIP18_OE plants to UV-B stress. Overall, we identified a positive regulator of serotonin biosynthesis and demonstrated that UV-B-stress induced serotonin accumulation, partly in an OsbZIP18-dependent manner
Volcanism, redox conditions, and microbialite growth linked with the end-Permian mass extinction: Evidence from the Xiajiacao section (western Hubei Province), South China
© 2017. A new Permian-Triassic boundary microbialite (PTBM) is described from the Xiajiacao section of western Hubei Province, South China. The new microbialite, 3.16. m thick, comprises a thin layer of stromatolite and a thick thrombolite unit. An irregular contact separates the uppermost Permian skeletal packstone from the post-extinction stromatolite, but it is not yet possible to discriminate whether it was formed by submarine solution in the wake of ocean acidification or subaerial exposure due to regional regression, or a combination of both. The stromatolite shows "cabbage-like" morphology, and the thrombolite is characterized by centimetric clotted texture. Abundant columns of the microproblematica structure Gakhumella, coccoid-like spheroids, bacterial clump-like spheroids, and hollow spheroids are recognized in both stromatolites and thrombolites and may have played an important role in accretion of the microbialites. Pyrite framboid analysis indicates that microbialites may have been affected by lower dysoxic to upper dysoxic conditions in the immediate aftermath of the Permian-Triassic extinction. Stratigraphic abundance of both high-temperature grains (β-quartz and glassy balls) peaked ~. 20. cm below the biotic extinction horizon, implying that either intensive volcanic eruption occurred only just prior to biotic extinction, or volcanism was still intensive during biotic extinction, but volcanic grains were not deposited in the Xiajiacao locality, likely due to the shallow, agitated environment caused by the regional regression. Overall, microbial bloom, indicated by the widespread PTBMs, seems to have been little affected by the contemporaneous volcanism.We thank both anonymous reviewers and editor Thomas Algeo for critical
comments and constructive suggestions, which have greatly improved the quality of
the paper. This study is partly supported by the 111 Program of China (B08030), two
NSFC grants (41572091, 41402089), and one research grant from the State Key
Laboratory of Biogeology and Environmental Geology (BGEG), China University of
Geosciences (GBL11206). It is a contribution to the IGCP 630 “Permian–Triassic
climatic and environmental extremes and biotic response”
Genetic- and fiber-diet-mediated changes in virulence factors in pig colon contents and feces and their driving factors
Virulence factors (VFs) are key factors for microorganisms to establish defense mechanisms in the host and enhance their pathogenic potential. However, the spectrum of virulence factors in pig colon and feces, as well as the influence of dietary and genetic factors on them, remains unreported. In this study, we firstly revealed the diversity, abundance and distribution characteristics of VFs in the colonic contents of different breeds of pigs (Taoyuan, Xiangcun and Duroc pig) fed with different fiber levels by using a metagenomic analysis. The analysis resulted in the identification of 1,236 virulence factors, which could be grouped into 16 virulence features. Among these, Taoyuan pigs exhibited significantly higher levels of virulence factors compared to Duroc pigs. The high-fiber diet significantly reduced the abundance of certain virulence factor categories, including iron uptake systems (FbpABC, HitABC) and Ig protease categories in the colon, along with a noteworthy decrease in the relative abundance of plasmid categories in mobile genetic elements (MGEs). Further we examined VFs in feces using absolute quantification. The results showed that high-fiber diets reduce fecal excretion of VFs and that this effect is strongly influenced by MGEs and short-chain fatty acids (SCFAs). In vitro fermentation experiments confirmed that acetic acid (AA) led to a decrease in the relative abundance of VFs (p < 0.1). In conclusion, our findings reveal for the first time how fiber diet and genetic factors affect the distribution of VFs in pig colon contents and feces and their driving factors. This information provides valuable reference data to further improve food safety and animal health
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