Metallic ureteral stents: a cost effective management in malignant ureteric obstruction

Moderated Poster (Free Paper) Session 1 - Uro-Oncology: no. MP.1-2OBJECTIVE: For patients requiring long-term ureteral stenting, conventional polymer stents necessitate multiple exchanges per year, bearing significant financial cost and likely detrimental effect on patients’ health. We report our experience with Resonance (Cook) metallic ureteral stent and present a cost analysis on its usage …postprin

Relationship between volume – adjusted prostate-specific antigen and pathologic Gleason Score

Moderated Poster Session I2: Prostate Cancer: Markers, Prevention and StagingThe abstract can be viewed at: http://www.siucongress.org/2014/abstracts

Prostate volume estimation in prostate cancer: are urologists or radiologists more accurate?

Oral Presentatio

High-risk prostate cancer: what can we expect after prostatectomy?

Abstract and Oral Presentation: Oral (Free Paper) Session II: Uro-oncology: Prostate / Kidney; abstract no.OP.2-

Usefulness of magnetic resonance imaging volume-adjusted serum prostate-specific antigen in predicting pathological outcome of prostate cancer

Poster Presentation10th World Chinese Urological Society (WCUS) Meeting, 16 May 2015 NOMCC: 356-35

NMR-based metabolomic urinalysis: A rapid screening test for urinary tract infection

Background: Urinary tract infection (UTI) is one of the most common bacterial infections in humans; however, there is no accurate and fast quantitative test to detect UTI. Dipstick urinalysis is semi-quantitative with a limited diagnostic accuracy, while urine culture is accurate but takes time. We described a quantitative biochemical method for the diagnosis of bacteriuria using a single marker. Methods: We compared the urine metabolomes from 88 patients with bacterial UTI and 61 controls using 1H NMR spectroscopy followed by principal component analysis (PCA) and orthogonal partial least squares-discriminant analysis (OPLS-DA). The biomarker identified was subsequently validated using independent samples. Results: The urine acetic acid/creatinine (mmol/mmol) level was determined to be the most discriminatory marker for bacterial UTI with an area-under-receiver operating characteristic curve. =. 0.97, sensitivity. =. 91% and specificity. =. 95% at the optimal cutoff 0.03. mmol/mmol. For validation, 60 samples were recruited prospectively. Using the optimal cutoff for acetic acid/creatinine, this method showed sensitivity. =. 96%, specificity. =. 94%, positive predictive value. =. 92%, negative predictive value. =. 97% and an overall accuracy. =. 95%. The diagnostic performance was superior to dipstick urinalysis or microscopy. In addition, we also observed an increase of urinary trimethylamine (TMA) in patients with Escherichia coli-associated UTI. TMA is a mammalian-microbial co-metabolite and the high level of TMA generated is related to the bacterial enzyme, trimethylamine N-oxide (TMAO) reductase which reduces TMAO to TMA. Conclusions: Urine acetic acid is a neglected metabolite that can be used for rapid diagnosis of UTI and TMA can be used for etiologic diagnosis of UTI. With the introduction of NMR-based clinical analyzers to clinical laboratories, NMR-based urinalysis can be translated for clinical use. © 2014 Elsevier B.V

A prospective review of outcomes of metallic ureteric stents

Abstract and Oral Presentation: Oral (Free Paper) Session III: Andrology / Stone & Infection / Stents: abstract no. OP.3-

Retrospective review of 15 years of Fournier’s Gangrene in QMH & KWH

Congress Theme: Surgery for Tomorrow's AsiaAbstract and Poster Presentation: no. P10

The optimal prostate-specific antigen and prostate-specific antigen density cut-off levels for Chinese men to consider transrectal ultrasound-guided prostate biopsy

Poster Presentation10th World Chinese Urological Society (WCUS) Meeting, 16 May 2015 NOMCC : 356-35

Pattern of use of serum prostate-specific antigen (PSA) among different clinical specialties: retrospective study in a tertiary hospital

Abstract and Poster PresentationThis free Journal suppl. entitled: Special Issue: Abstracts of the Hong Kong Urological Association, 22nd Annual Scientific Meeting, 20 November 2016, Hong KongOBJECTIVE: The Urology Clinic at our unit receives many referrals for raised PSA. The study focused on why PSA was checked initially, whether it was clinically indicated or affected patient management. PATIENTS AND METHODS: This was a single center cross-sectional study on all whose PSA were checked from January 2014 to March 2014. Patient demographics, requesting specialty, indications of checking PSA were extracted from clinical records. PSA results and patients’ clinical outcomes were followed up. RESULTS: 2104 PSA requests of whose mean age 69.6 years old were reviewed. Mean PSA was 36.37 ng/mL (median 2.7 ng/mL). 429(20.4%, 2014) had elevated PSA (>4 ng/mL). 386(90%, 429) were subsequently managed at the Urology Clinic. 128 patients (29.8%, 429) underwent trans-rectal ultrasound guided prostate biopsy. 49 patients (38%, 128) were diagnosed with prostate cancer, of which 23 (46.9%, 49) opted for radical treatment – 10(43.5%, 23) underwent radical prostatectomy, 13(56.5%, 23) had radiotherapy. Logistic analysis showed that age and stage of disease were significantly higher in whom underwent radiotherapy. Age was the only statistically significant predictor for prostate cancer (p = 0.001). Others factors, like PSA level, requesting specialty and clinical indications were not predictors for prostate cancer detection. CONCLUSION: Inappropriate PSA testing is widespread at our institute. Patient counselling is important prior to its checking as to understand the implications of raised PSA levels.link_to_OA_fulltex