マスク用エアフィルタの高性能化と評価技術に関する研究

13301甲第4326号博士（工学）金沢大学博士論文本文Ful

マスク用エアフィルタの高性能化と評価技術に関する研究

13301甲第4326号博士（工学）金沢大学博士論文要旨Abstrac

Filtration properties of nanofiber/microfiber mixed filter and prediction of its performance

There is an increasing demand of air filters with a high collection performance, i.e., high collection efficiency and low pressure drop, for the application to indoor air cleaning. Air filters consisting of nanofibers have attracted great interests since they may have a low pressure drop because of slip flow effect and high collection efficiency due to interception. Although various nanofiber filters are available on the market, their collection performance is not as high as expected by the conventional filtration theory because non-uniform packing of fibers plays a significant role. In the present work, the collection performance of nanofiber (780 nm) and microfiber (11.2 µm) mixed filters with various mixing fractions was studied in order to maximize the quality factor of filter, qF, as a function of mixing fraction of nanofibers. The collection performance of mixed fiber filters was predicted by using theoretical equations reported by Bao et al. (1998) for bimodal distribution of fibers. As a result, it was found that the mixed fiber filters had a uniform fiber packing compared to laminated filters and that the collection efficiency was well predicted by introducing the inhomogeneity factor calculated for the filter consisting of two distinct fiber sizes. Furthermore, we found that the mixed fiber filter with the nanofiber mixing fraction of 5% in mass had the highest quality factor. © Taiwan Association for Aerosol Research

ホウシャセン チリョウ ガ コウカテキ デ アッタ チョクチョウナイ ブンピツ サイボウ ガン ノ 1 レイ

A 54-year-old woman was seen at the hospital because of anal bleeding. Colonoscopy examination showed a type 2 tumor in the lower rectum and the histological diagnosis from the biopsy specimen was undifferenciated adenocarcinoma. Abdomino-perineal amputation of the rectum were performed. The resected specimen was positive for synaptophysin stain immunohistochemically and we diagnosed it as an endocrine cell carcinoma. We underwent adjuvant chemotherapy by bolus CPT-11, and the post operative course was uneventful. Intra-pelvic recurrence was observed 15 months after operation, and further 4 months later, metastasis developed around the pancreas. And we noticed the tumor in supraclavicular region 21 months after operation. The tumor was sensitive to chemotherapy, but continued to progress. So we underwent radiotherapy for each lesion. The lesion treated with radiotherapy were controlled until she died of cancer, 31 months after the operation. As a result of autopsy, an exellent effect of radiotherapy was confirmed

ショクドウガン ジュツゴ ソウキ ニ キカン イカンロウ オ ガッペイ シタ 1レイ

The patient was a４５-year-old man. He had suffered from nephrotic syndrome at time of his twenties and had steroid salvage treatment. But he retired the treatment by himself. Esophageal tumor was suspected at the screening, and he was referred to our hospital. Preoperative diagnosis was the adenocarcinoma of the esophagogastric junction（cT２N０M０ stage Ⅱ）． Thoracoscopy assisted subtotal esophagectomy in prone position with D２dissection was performed. Gastric role was prepared in laparoscopic approach, and pulled up to the neck via posterior mediastinal route. Although early postoperative course was uneventful and esophageal fluoroscopy on the７th day showed no leakage, sudden dyspnea appeared on the８th day. CT examination and Bronchoscopy showed tracheoesophageal fistula. Unfortunately, the fistula didn’t get well, and we considered that it was difficult to close the fistula by only conservative treatment. Esophageal covered stent was inserted on the５６th day. After that, he could start ingestion intake and was discharged from hospital on the８５th day. Now, he is being followed up in our hospital

チュウスイ ゲンパツ フクゴウガタ セン シンケイ ナイブンピツ ガン ノ イチチケンレイ

A５２-year-old man visited our hospital because of epigastralgia. The colonoscopic examination revealed an about ４cm-protruded lesion like SMT on the appendix and findings of the biopsy specimen were compatible with the disgnosis of signet ring cell carcinoma. The primary lesion was unknown by upper gastrointestinal endoscopy, CT and PET, and the tumor markers were normal revel. At laparotomy, severe peritoneal metastasis was revealed in the abdominal cavity, especially appendix. Severe stenosis of ileocecum was found, so we conducted ileocecal resection. The histopathological diagnosis was primary signet ring cell caicinoma of appendix, SE, N２, M０, P３, pStage Ⅳ. Postoperatively mFOLFOX was started, but allergic reaction was seen after１cycle. We started Panitumumab/CPT-１１and the patient attended our emergency department with shivering chill and fever on treatment day１０. The next day he became shock state and CT revealed free air. Operation might not save his life and we started supportive care. He died on the day. The cause of his death was peritonitis by cancer perforation