19 research outputs found

    A Multidomain Survivable Virtual Network Mapping Algorithm

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    Although the existing networks are more often deployed in the multidomain environment, most of existing researches focus on single-domain networks and there are no appropriate solutions for the multidomain virtual network mapping problem. In fact, most studies assume that the underlying network can operate without any interruption. However, physical networks cannot ensure the normal provision of network services for external reasons and traditional single-domain networks have difficulties to meet user needs, especially for the high security requirements of the network transmission. In order to solve the above problems, this paper proposes a survivable virtual network mapping algorithm (IntD-GRC-SVNE) that implements multidomain mapping in network virtualization. IntD-GRC-SVNE maps the virtual communication networks onto different domain networks and provides backup resources for virtual links which improve the survivability of the special networks. Simulation results show that IntD-GRC-SVNE can not only improve the survivability of multidomain communications network but also render the network load more balanced and greatly improve the network acceptance rate due to employment of GRC (global resource capacity)

    Novel Magnetic-to-Thermal Conversion and Thermal Energy Management Composite Phase Change Material

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    Superparamagnetic materials have elicited increasing interest due to their high-efficiency magnetothermal conversion. However, it is difficult to effectively manage the magnetothermal energy due to the continuous magnetothermal effect at present. In this study, we designed and synthesized a novel Fe3O4/PEG/SiO2 composite phase change material (PCM) that can simultaneously realize magnetic-to-thermal conversion and thermal energy management because of outstanding thermal energy storage ability of PCM. The composite was fabricated by in situ doping of superparamagnetic Fe3O4 nanoclusters through a simple sol–gel method. The synthesized Fe3O4/PEG/SiO2 PCM exhibited good thermal stability, high phase change enthalpy, and excellent shape-stabilized property. This study provides an additional promising route for application of the magnetothermal effect

    Collection and annotation of Malay conversational speech corpus

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    We report the development of a Malay conversational speech corpus as part of our research in spontaneous conversational speech LVCSR. This corpus development effort is the collaboration between NTU and USM. The goal is to collect, transcribe, and annotate 50 hours of conversational Malay speech. The conversation is recorded from both close-talk and telephone channels, and both speakers' utterances are kept in separate tracks. Besides the word transcription, we also annotate linguistics phenomena such as fillers and disfluencies. To date, 20 hours have been recorded, transcribed and analyzed. The details of our analysis will be presented in this report

    Strategic application of CuAAC click chemistry in the modification of natural products for anticancer activity

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    Natural products play a key role in the history of human drug discovery, and especially for the anticancer agents. Copper(I)-catalyzed alkyne-azide [3+2] cycloaddition (CuAAC) reaction is perhaps the most powerful method for the efficient modification of complex natural products, enabling the direct incorporation of various functional groups accompanied by the formation of the multifunctional 1,2,3-triazole motif, which could not only serve as an basic and hydrophilic connecting group but also as a bioisosteres of 5- or 6-membered heterocycles or an amide group, thus facilitating the improvement of anticancer activities and/or drug-like properties. This contribution extensively summarizes the state-of-the-art application of 1,2,3-triazole in the modification of natural products for anticancer activity. The aim is to gain a deep understanding of the fruitful achievements as well as limitations of CuAAC click chemistry in natural product modification for anticancer activity, and provide perspectives and directions regarding future studies in natural product medicinal chemistry
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