5,877 research outputs found
Size effect of Ruderman-Kittel-Kasuya-Yosida interaction mediated by electrons in nanoribbons
We calculated the Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction between
the magnetic impurities mediated by electrons in nanoribbons. It was shown that
the RKKY interaction is strongly dependent on the width of the nanoribbon and
the transverse positions of the impurities. The transverse confinement of
electrons is responsible for the above size effect of the RKKY interaction. It
provides a potential way to control the RKKY interaction by changing
nanostructure geometry
A novel culture system for modulating single cell geometry in 3D
Dedifferentiation of chondrocytes during in vitro expansion remains an unsolved challenge for repairing serious articular cartilage defects. In this study, a novel culture system was developed to modulate single cell geometry in 3D and investigate its effects on the chondrocyte phenotype. The approach uses 2D micropatterns followed by in situ hydrogel formation to constrain single cell shape and spreading. This enables independent control of cell geometry and extracellular matrix. Using collagen I matrix, we demonstrated the formation of a biomimetic collagenous “basket” enveloping individual chondrocytes cells. By quantitatively monitoring the production by single cells of chondrogenic matrix (e.g. collagen II and aggrecan) during 21-day cultures, we found that if the cell’s volume decreases, then so does its cell resistance to dedifferentiation (even if the cells remain spherical). Conversely, if the volume of spherical cells remains constant (after an initial decrease), then not only do the cells retain their differentiated status, but previously de-differentiated redifferentiate and regain a chondrocyte phenotype. The approach described here can be readily applied to pluripotent cells, offering a versatile platform in the search for niches toward either self-renewal or targeted differentiation
The current research status of normal tension glaucoma
Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlying NTG in both animal models and human patients. We also proposed that the neurovascular unit is a therapeutic target for NTG management.published_or_final_versio
Boundary points, minimal integrals and concavity property III---linearity on Riemann surfaces
In this article, we consider a modified version of minimal integrals on
sublevel sets of plurisubharmonic functions related to modules at boundary
points, and obtain a concavity property of the modified version. As an
application, we give a characterization for the concavity degenerating to
linearity on open Riemann surfaces.Comment: 48 pages, all comments are welcome. arXiv admin note: substantial
text overlap with arXiv:2203.0772
Concavity property of minimal integrals with Lebesgue measurable gain II
In this article, we present a concavity property of the minimal
integrals related to multiplier ideal sheaves with Lebesgue measurable gain on
weakly pseudoconvex K\"ahler manifolds. As applications, we give a necessary
condition for the concavity degenerating to linearity, and a characterization
for the holding of the equality in optimal jets extension problem on open
Riemann surfaces.Comment: 48 pages, comments are welcomed. arXiv admin note: substantial text
overlap with arXiv:2209.0363
Optimal extension for holomorphic vector bundles with singular hermitian metrics
In the present paper, we study the properties of singular Nakano positivity
of singular hermitian metrics on holomorphic vector bundles, and establish an
optimal extension theorem for holomorphic vector bundles with singular
hermitian metrics on weakly pseudoconvex K\"{a}hler manifolds. As applications,
we give a necessary condition for the holding of the equality in optimal
extension theorem, and present singular hermitian holomorphic vector bundle
versions of some extension theorems with optimal estimate.Comment: 76pages, comments are welcomed. Some typos are correcte
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