64,915 research outputs found

    A Data Exchange Standard for Optical (Visible/IR) Interferometry

    Full text link
    This paper describes the OI Exchange Format, a standard for exchanging calibrated data from optical (visible/infrared) stellar interferometers. The standard is based on the Flexible Image Transport System (FITS), and supports storage of the optical interferometric observables including squared visibility and closure phase -- data products not included in radio interferometry standards such as UV-FITS. The format has already gained the support of most currently-operating optical interferometer projects, including COAST, NPOI, IOTA, CHARA, VLTI, PTI, and the Keck Interferometer, and is endorsed by the IAU Working Group on Optical Interferometry. Software is available for reading, writing and merging OI Exchange Format files.Comment: 26 pages, 1 figur

    It's all in the name, or is it? The impact of labelling on health state values

    Get PDF
    Many descriptions of health used in vignettes and condition-specific measures refer to the medical condition. This paper assesses the impact of referring to the medical condition in the descriptions of health states valued by members of the general population. A sample of 241 members of the UK general population each valued 8 health states using time trade-off. All respondents valued essentially the same health states, but for each respondent the descriptions featured either an irritable bowel syndrome label, a cancer label or no label. Regression techniques were used to estimate the impact of each label and experience of the condition on health state values. We find that the inclusion of a cancer label in health state descriptions affects health state values and that the impact is dependent upon the severity of the state. A condition label can affect health state values, but this is dependent upon the specific condition and severity. It is recommended to avoid condition labels in health state descriptions (where possible) to ensure that values are not affected by prior knowledge or preconception of the condition that may distort the health state being valued

    Making Rasch decisions: The use of Rasch analysis in the construction of preference based health related quality of life instruments

    Get PDF
    Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation. Methods: The overactive bladder questionnaire is used to illustrate a four step process for deriving a reduced health state classification from an existing nonpreference based health related quality of life instrument. Step I excludes items that do not meet the initial validation process and step II uses criteria based on Rasch analysis and psychometric testing to select the final items for the health state classification. In step III, item levels are examined and Rasch analysis is used to explore the possibility of reducing the number of item levels. Step IV repeats steps I to III on alternative data sets in order to validate the selection of items for the health state classification. Conclusions: The techniques described enable the construction of a health state classification amenable for valuation exercises that will allow the derivation of preference weights. Thus, the health related quality of life of patients with conditions, like overactive bladder, can be valued and quality adjustment weights such as quality adjusted life years derived

    The use of Rasch analysis as a tool in the construction of a preference based measure: the case of AQLQ

    Get PDF
    The majority of quality of life instruments are not preference-based measures and so cannot be used within cost utility analysis. The Asthma Quality of Life Questionnaire (AQLQ) is one such instrument. The aim of this study was to develop a health state classification that is amenable to valuation from the AQLQ. Rasch models were applied to samples of responders to the AQLQ with the aim of i) selecting a number of items for a preference based utility measure (AQL-5D), ii) reducing the number of levels for each item to a more manageable number of levels for establishing AQL-5D. Selection of items for the evaluation survey was supported with conventional psychometric criteria for item selection (feasibility, internal consistency, floor and ceiling effects, responsiveness and regression against overall health). The role of Rasch analysis in reducing the number of item levels to a preconceived target number of levels proved unsuccessful. However, Rasch analysis proved to be a useful tool in assisting in the initial process of selecting items from an existing HRQL instrument in the construction of AQL-5D. The method is recommended for use alongside conventional psychometric testing to aid in the development of preference-based measures

    Making Rasch decisions: The use of Rasch analysis in the construction of preference based health related quality of life instruments

    Get PDF
    Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation. Methods: The overactive bladder questionnaire is used to illustrate a four step process for deriving a reduced health state classification from an existing nonpreference based health related quality of life instrument. Step I excludes items that do not meet the initial validation process and step II uses criteria based on Rasch analysis and psychometric testing to select the final items for the health state classification. In step III, item levels are examined and Rasch analysis is used to explore the possibility of reducing the number of item levels. Step IV repeats steps I to III on alternative data sets in order to validate the selection of items for the health state classification. Conclusions: The techniques described enable the construction of a health state classification amenable for valuation exercises that will allow the derivation of preference weights. Thus, the health related quality of life of patients with conditions, like overactive bladder, can be valued and quality adjustment weights such as quality adjusted life years derived

    It's all in the name, or is it? The impact of labelling on health state values

    Get PDF
    Many descriptions of health used in vignettes and condition-specific measures refer to the medical condition. This paper assesses the impact of referring to the medical condition in the descriptions of health states valued by members of the general population. A sample of 241 members of the UK general population each valued 8 health states using time trade-off. All respondents valued essentially the same health states, but for each respondent the descriptions featured either an irritable bowel syndrome label, a cancer label or no label. Regression techniques were used to estimate the impact of each label and experience of the condition on health state values. We find that the inclusion of a cancer label in health state descriptions affects health state values and that the impact is dependent upon the severity of the state. A condition label can affect health state values, but this is dependent upon the specific condition and severity. It is recommended to avoid condition labels in health state descriptions (where possible) to ensure that values are not affected by prior knowledge or preconception of the condition that may distort the health state being valued

    The optical variability of the narrow line Seyfert 1 galaxy IRAS 13224-3809

    Get PDF
    We report on a short optical monitoring programme of the narrow-line Seyfert 1 Galaxy IRAS 13224-3809. Previous X-ray observations of this object have shown persistent giant variability. The degree of variability at other wavelengths may then be used to constrain the conditions and emission processes within the nucleus. Optical variability is expected if the electron population responsible for the soft X-ray emission is changing rapidly and Compton-upscattering infrared photons in the nucleus, or if the mechanism responsible for X-ray emission causes all the emission processes to vary together. We find that there is no significant optical variability with a firm upper limit of 2 per cent and conclude that the primary soft X-ray emission region produces little of the observed optical emission. The X-ray and optical emission regions must be physically distinct and any reprocessing of X-rays into the optical waveband occurs some distance from the nucleus. The lack of optical variability indicates that the energy density of infrared radiation in the nucleus is at most equal to that of the ultraviolet radiation since little is upscattered into the optical waveband. The extremely large X-ray variability of IRAS 13224-3809 may be explained by relativistic boosting of more modest variations. Although such boosting enhances X-ray variability over optical variability, this only partially explains the lack of optical variability.Comment: 5 pages with 8 postscript figures. Accepted for publication in MNRA
    corecore