6,606 research outputs found

    U.S v. City of Indianapolis

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    U_S__v__City_of_Indianapolis_ABBYY.pdf: 45 downloads, before Oct. 1, 2020

    AN ECONOMIC EVALUATION OF THE COLORADO RIVER BASIN SALINITY CONTROL PROGRAM

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    Dissolved salts (salinity) adversely affect numerous urban and agricultural users of Colorado River water in California and Arizona. Congress in 1974 authorized a major salinity control program. Studies of general economic benefits from salinity abatement and the cost per unit of salinity reduction expected from specific proposed projects have been developed by the responsible federal agencies, but no project-by-project evaluation has been published. We find a conceptual basis for a substantial downward revision of prospective economic benefits of salinity abatement. Revised benefits are compared with estimated costs, and only for five of the nineteen projects do economic benefits appear to exceed costs.Resource /Energy Economics and Policy,

    The Effects of Private Self-Consciousness and Perspective Taking on Satisfaction in Close Relationships.

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    131 heterosexual student couples, aged 17–32 yrs, 30 of whom were married or engaged answered questions concerning themselves and their relationships. It was predicted that individual differences in private self-consciousness would be positively related to relationship satisfaction because of the greater self-disclosure resulting from that heightened self-attention. It was further predicted that individual differences in perspective taking would foster relationship satisfaction, independent of any influence of self-disclosure. Both expectations were confirmed. Scores on the private self-consciousness scale were predictive of reported self-disclosure, and self-disclosure was predictive of satisfaction in the relationship. Once the influence of self-disclosure was removed, no effect of self-consciousness on satisfaction remained. In contrast, after disclosure was controlled, perspective-taking scores were significantly related to satisfaction and were in fact unrelated to disclosure at all. Findings indicate that 2 personality characteristics having to do with habitual attention to behavioral tendencies, emotions, and motivations significantly enhance the quality of close heterosexual relationships in different ways

    Sensing via Intestinal Sweet Taste Pathways

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    The detection of nutrients in the gastrointestinal (GI) tract is of fundamental significance to the control of motility, glycemia and energy intake, and yet we barely know the most fundamental aspects of this process. This is in stark contrast to the mechanisms underlying the detection of lingual taste, which have been increasingly well characterized in recent years, and which provide an excellent starting point for characterizing nutrient detection in the intestine. This review focuses on the form and function of sweet taste transduction mechanisms identified in the intestinal tract; it does not focus on sensors for fatty acids or proteins. It examines the intestinal cell types equipped with sweet taste transduction molecules in animals and humans, their location, and potential signals that transduce the presence of nutrients to neural pathways involved in reflex control of GI motility

    Habitat Relationships of Landbirds in the Northern Region, USDA Forest Service

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    A series of first-generation habitat-relationships models for 83 bird species were detected in a 3-year study on point counts conducted in association with the USDA Forest Service\u27s Northern Region Landbird Monitoring Program. The models depict probabilities of detection for each of the bird species on 100-m-radius, 10-minute point counts conducted across a series of major vegetation cover types. Based on these models, some bird species appear to be restricted in their habitat distribution to: (1) postfire, standing-dead forests, (2) relatively uncut, older forests, (3) harvested forest types, (4) marshes, (5) riparian environments, and (6) grasslands and sagebrush. Such restricted distributions highlight the need to provide adequate amounts of these cover types to maintain viable species populations. Many bird species were relatively abundant in harvested forests, suggesting a need for nesting success studies because timber harvesting creates unnatural cover types that may elicit settling responses by species that are programmed to respond to similar naturally occurring cover types. Thus, these unnatural cover types could be acting as ecological traps, where species are being attracted to sites where suitability is relatively poor. These preliminary results demonstrate the utility of a landbird monitoring program, and suggest that agencies such as the Forest Service should consider broadening the indicator species concept to monitor groups of species (such as landbirds and butterflies) that can be easily sampled with a single field method. The list of species covered by this program is indeed large enough and ecologically broad enough to help managers predict and monitor the effects of management activities on almost all the major vegetation types in the region. The detail and region-specific nature of this information can be matched by no other database in existence on landbirds, and the information should prove useful to land managers in planning areas that might consist of alternative cover types

    Body Protection Systems for Use in Humanitarian Demining: Applying Hard Science and End-User Feedback to Improve Personal Protection for Deminers

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    Somewhere between the tightening budgets of program managers, myriad of demining activities, and fatigue among donors, lies a life-threatening issue which receives limited attention within the hierarchy of themes defining humanitarian demining. According to a large cross-section of deminers around the world, personal protection for deminers is considered a poor second cousin to such themes as mine awareness and victim assistance. They say the issue of improving personal protection needs to be pushed higher up the demining agenda

    Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine

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    Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background: Huntingtin-associated Protein 1 (HAP1) is expressed in neurons and endocrine cells, and is critical for postnatal survival in mice. HAP1 shares a conserved “HAP1_N” domain with TRAfficking Kinesin proteins TRAK1 and TRAK2 (vertebrate), Milton (Drosophila) and T27A3.1 (C. elegans). HAP1, TRAK1 and TRAK2 have a degree of common function, particularly regarding intracellular receptor trafficking. However, TRAK1, TRAK2 and Milton (which have a “Milt/TRAK” domain that is absent in human and rodent HAP1) differ in function to HAP1 in that they are mitochondrial transport proteins, while HAP1 has emerging roles in starvation response. We have investigated HAP1 function by examining its evolution, and upstream gene promoter sequences. We performed phylogenetic analyses of the HAP1_N domain family of proteins, incorporating HAP1 orthologues (identified by genomic synteny) from 5 vertebrate classes, and also searched the Dictyostelium proteome for a common ancestor. Computational analyses of mammalian HAP1 gene promoters were performed to identify phylogenetically conserved regulatory motifs. Results: We found that as recently as marsupials, HAP1 contained a Milt/TRAK domain and was more similar to TRAK1 and TRAK2 than to eutherian HAP1. The Milt/TRAK domain likely arose post multicellularity, as it was absent in the Dictyostelium proteome. It was lost from HAP1 in the eutherian lineage, and also from T27A3.1 in C. elegans. The HAP1 promoter from human, mouse, rat, rabbit, horse, dog, Tasmanian devil and opossum contained common sites for transcription factors involved in cell cycle, growth, differentiation, and stress response. A conserved arrangement of regulatory elements was identified, including sites for caudal-related homeobox transcription factors (CDX1 and CDX2), and myc-associated factor X (MAX) in the region of the TATA box. CDX1 and CDX2 are intestine-enriched factors, prompting investigation of HAP1 protein expression in the human duodenum. HAP1 was localized to singly dispersed mucosal cells, including a subset of serotonin-positive enterochromaffin cells. Conclusion: We have identified eutherian HAP1 as an evolutionarily recent adaptation of a vertebrate TRAK protein-like ancestor, and found conserved CDX1/CDX2 and MAX transcription factor binding sites near the TATA box in mammalian HAP1 gene promoters. We also demonstrated that HAP1 is expressed in endocrine cells of the human gut
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