(Dimethyl­formamide-κO)[2-meth­oxy-6-(2-pyridylmethyl­imino­meth­yl)phenolato-κ3 N,N′,O 1](thio­cyanato-κN)copper(II)

In the title compound, [Cu(C14H13N2O2)(NCS)(C3H7NO)], the Cu2+ ion is coordinated by an N,N′,O-tridentate 2-meth­oxy-6-(2-pyridylmethyl­imino­meth­yl)phenolate ligand, an N-bonded thio­cyanate ion and an O-bonded dimethyl­formamide (DMF) mol­ecule, resulting in a distorted CuN3O2 square-based pyramidal geometry for the metal ion, with the DMF O atom in the apical site. The dihedral angle between the aromatic rings in the ligand is 8.70 (16)°. The S atom is disordered over two positions in a 0.901 (6):0.099 (6) ratio. In the crystal, mol­ecules inter­act by way of π–π stacking inter­actions [centroid–centroid separation = 3.720 (2) Å]

2-Hydr­oxy-N′-(2-hydr­oxy-4-methoxy­benzyl­idene)-3-methyl­benzohydrazide monohydrate

In the title compound, C16H16N2O4·H2O, the dihedral angle between the two benzene rings is 12.4 (2)° and the mol­ecule adopts an E configuration with respect to the C=N bond. There are intra­molecular O—H⋯N and O—H⋯O hydrogen bonds in the hydrazone mol­ecule, which both generate S(6) rings. In the crystal structure, mol­ecules are linked by N—H⋯O and O—H⋯O hydrogen bonds, forming layers parallel to the ab plane. The crystal studied was a non-merohedral twin with a domain ratio of 0.887 (3):0.113 (3)

2,2-Dimethyl-5-[(pyridin-2-yl­amino)­methyl­idene]-1,3-dioxane-4,6-dione

In the title compound, C12H12N2O4, the dihedral angle between the pyridine and enamine planes is 3.5 (3)°, while the angle between the dioxanedione (seven atoms) and enamine planes is 4.6 (3)°. The dioxane ring approximates an envelope conformation

Mechanisms of Competitive Adsorption Organic Pollutants on Hexylene-Bridged Polysilsesquioxane

Hexylene-bridged periodic mesoporous polysilsesquioxanes (HBPMS) are a promising new class of adsorbent for the removal of organic contaminants from aqueous solutions. These hybrid organic-inorganic materials have a larger BET surface area of 897 m2·g−1 accessible through a cubic, isotropic network of 3.82-nm diameter pores. The hexylene bridging group provides enhanced adsorption of organic molecules while the bridged polysilsesquioxane structure permits sufficient silanols that are hydrophilic to be retained. In this study, adsorption of phenanthrene (PHEN), 2,4-Dichlorophenol (DCP), and nitrobenzene (NBZ) with HBPMS materials was studied to ascertain the relative contributions to adsorption performance from (1) direct competition for sites and (2) pore blockage. A conceptual model was proposed to further explain the phenomena. This study suggests a promising application of cubic mesoporous BPS in wastewater treatment

Pair Production of Charged Higgs Bosons from Bottom-Quark Fusion

For very large values of $\tan\beta$, charged Higgs boson pair production at the Large Hadron Collider (LHC) from the scattering of two bottom quarks can proceed dominantly. We investigated the cross sections of charged Higgs boson pair production via the subprocess $b\bar{b} \to H^+H^-$ at the LHC including the next-to-leading order (NLO) QCD corrections in the minimal supersymmetric standard model (MSSM). We find that the NLO QCD corrections can significantly reduce the dependence of the cross sections on the renormalization and factorization scales.Comment: small changes are mad

Integrated analysis of long non-coding RNAs and mRNAs associated with glaucoma in vitro

IntroductionIn recent years, the biological functions and important roles of long non-coding RNAs (lncRNAs) have been widely reported in many diseases. Although glaucoma is the leading cause of blindness worldwide, the specific mechanisms of lncRNAs in the pathogenesis and progression of glaucoma remain unclear. Our research aims to elucidate the differentially expressed lncRNAs and mRNAs in glaucoma and to provide a basis for further exploration of the specific mechanism of action of lncRNAs in the progression of glaucoma.MethodsWe performed RNA sequencing on samples from a pressurized model of R28 cells and performed bioinformatics analyses on the sequencing results. The expression consistency of lncRNAs in clinical samples from patients with glaucoma or cataracts was detected using real-time quantitative polymerase chain reaction (RT-qPCR).ResultsRNA sequencing results showed that lncRNAs in cluster 5 were upregulated with increasing stress after typing all significantly altered lncRNAs using k-means in a cellular stress model. KEGG analysis indicated that they were associated with neurodegenerative diseases. Differentially expressed lncRNAs were verified by RT-qPCR, and the lncRNA expression levels of AC120246.2 and XLOC_006247 were significantly higher in the aqueous humor (AH) of patients with glaucoma than in those with cataracts. For LOC102551819, there was almost no expression in the AH and trabecular meshwork in patients with glaucoma but high expression was observed in the iris. ConclusionOur research proposes potential diagnostic or intervention targets for clinical applications as well as a theoretical basis for more in-depth research on the function of lncRNAs in glaucoma