152 research outputs found

    An Analysis of Factors Influencing Consumers\u27 Continued Purchase Intention Based on Online Shopping Pre-sale Mode

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    Online shopping pre-sale has great commercial value, and the key is to realize its commercial value,which is shown by the continuous purchase made by consumers. However, in China, there is a lack of relevant research on the factors affecting consumers\u27 continued purchase intention. Based on the expectation confirmation theory, this paper constructs a model to explore the influential factors of the consumer\u27s continued purchase intention. This study employed the Structural Equation Model (SEM) to perform empirical analysis. The results showed that the main influential factors of consumer’s continued purchase intention include perceived usefulness, perceived ease of use, expectation confirmation, and satisfaction. Among which, satisfaction had relatively high influence while perceived usefulness had a relatively low influence. Perceived usefulness and perceived ease of use had an indirect effect on the continued purchase intention through satisfaction

    Research on the Influence of Pinduoduo Group-Buying Mode on Consumers\u27 Impulse Buying

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    Social commerce, with its unique social attributes, has promoted the group-buying mode to become an important marketing tool. Based on the stimulus-organism-response (S-O-R) paradigm, this study constructs a research model of the impact of the social e-commerce platform Pinduoduo group-buying mode on impulse buying, and uses structural equation model (SEM) for empirical analysis. The research results show that under the group-buying mode: perceived price fairness and reciprocity have significant positive influence on satisfaction; source credibility and similarity have positive effects on trust. Trust is positively correlated with satisfaction. Trust significantly affects impulsive buying impulse, but satisfaction has no significant impact on impulsive buying impulse

    Optimization of a Decellularization/Recellularization Strategy for Transplantable Bioengineered Liver

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    The liver is a complex organ that requires constant perfusion for the delivery of nutrients and oxygen and the removal of waste in order to survive. Efforts to recreate or mimic the liver microstructure via a ground-up approach are essential for liver tissue engineering. A decellularization/recellularization strategy is one of the approaches aiming at the possibility of producing a fully functional organ with in vitro-developed construction for clinical applications to replace failed livers, such as end-stage liver disease (ESLD). However, the complexity of the liver microarchitecture along with the limited suitable hepatic component, such as the optimization of the extracellular matrix (ECM) of the biomaterials, the selection of the seed cells, and development of the liver-specific three-dimensional (3D) niche settings, pose numerous challenges. In this chapter, we have provided a comprehensive outlook on how the physiological, pathological, and spatiotemporal aspects of these drawbacks can be turned into the current challenges in the field, and put forward a few techniques with the potential to address these challenges, mainly focusing on a decellularization-based liver regeneration strategy. We hypothesize the primary concepts necessary for constructing tissue-engineered liver organs based on either an intact (from a naĂŻve liver) or a partial (from a pretreated liver) structure via simulating the natural development and regenerative processes

    CPIN:Comprehensive present-interest network for CTR prediction

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    Personalized recommendation is a popular research direction in both industry and academia. Some research on recommender systems utilizes the users’ interaction history on items to represent the users’ interests, which has achieved remarkable success. Users’ interests in the real world are dynamically changing and have a strong correlation with the interaction sequence. However, sometimes users’ interests are less relevant to the order of the current interaction sequence, but are more relevant to certain items in the user interaction history. In this paper, a novel deep neural network model is proposed to deal with this situation. The developed model consists of two parts: the present interest relevant to the order of the interaction sequence and the comprehensive interest relevant to some items in the interaction sequence. An ancillary multi-layer perceptron (MLP) is constructed to improve the training of our model. Experiments on public and industrial datasets are conducted. The experimental results show that our proposed model outperforms the state-of-the-art models which demonstrates the effectiveness of the ancillary MLP

    Dynamics of Fecal Coliform Bacteria along Canada's Coast

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    The vast coastline provides Canada with a flourishing seafood industry including bivalve shellfish production. To sustain a healthy bivalve molluscan shellfish production, the Canadian Shellfish Sanitation Program was established to monitor the health of shellfish harvesting habitats, and fecal coliform bacteria data have been collected at nearly 15,000 marine sample sites across six coastal provinces in Canada since 1979. We applied Functional Principal Component Analysis and subsequent correlation analyses to find annual variation patterns of bacteria levels at sites in each province. The overall magnitude and the seasonality of fecal contamination were modelled by functional principal component one and two, respectively. The amplitude was related to human and warm-blooded animal activities; the seasonality was strongly correlated with river discharge driven by precipitation and snow melt in British Columbia, but such correlation in provinces along the Atlantic coast could not be properly evaluated due to lack of data during winter.Comment: 30 pages, 7 figures, 0 tabl

    An analytical approach to evaluate point cloud registration error utilizing targets

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    Point cloud registration is essential for processing terrestrial laser scanning (TLS) point cloud datasets. The registration precision directly influences and determines the practical usefulness of TLS surveys. However, in terms of target based registration, analytical point cloud registration error models employed by scanner manufactures are only suitable to evaluate target registration error, rather than point cloud registration error. This paper proposes an new analytical approach called the registration error (RE) model to directly evaluate point cloud registration error. We verify the proposed model by comparing RE and root mean square error (RMSE) for all points in three point clouds that are approximately equivalent

    Renal cell carcinoma of different pathological types in bilateral native kidneys of a kidney transplant recipient: A case report and literature review

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    Patients after kidney transplantation have a much higher risk of developing malignant tumors than the general population. And the native kidney is an organ relatively susceptible to malignant tumors after renal transplantation. However, the simultaneous development of bilateral renal tumors is very rare; especially the bilateral native kidneys harbor different pathological types of renal cell carcinoma (RCC). We report a case of a patient who developed malignant tumors in both native kidneys nearly 19 years after renal transplantation. This patient underwent bilateral laparoscopic radical nephrectomy, and postoperative pathological examination showed clear cell RCC on the left native kidney and papillary RCC on the right one. And the early detection and surgical treatment resulted in a good prognosis. The literature related to the diagnosis and treatment of bilateral RCC after renal transplantation is also reviewed

    Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences

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    Bacterial phosphorothioate (PT) DNA modifications are incorporated by Dnd proteins A-E and often function with DndF-H as a restriction-modification (R-M) system, as in Escherichia coli B7A. However, bacteria such as Vibrio cyclitrophicus FF75 lack dndF-H, which points to other PT functions. Here we report two novel, orthogonal technologies to map PTs across the genomes of B7A and FF75 with >90% agreement: single molecule, real-time sequencing and deep sequencing of iodine-induced cleavage at PT (ICDS). In B7A, we detect PT on both strands of G[subscript ps]AAC/G[subscript ps]TTC motifs, but with only 12% of 40,701 possible sites modified. In contrast, PT in FF75 occurs as a single-strand modification at C[subscript ps]CA, again with only 14% of 160,541 sites modified. Single-molecule analysis indicates that modification could be partial at any particular genomic site even with active restriction by DndF-H, with direct interaction of modification proteins with GAAC/GTTC sites demonstrated with oligonucleotides. These results point to highly unusual target selection by PT-modification proteins and rule out known R-M mechanisms.National Natural Science Foundation (China)Ministry of Science and Technology of the People's Republic of China (973 and 863 Programs)Shanghai Municipal Council of Science and Technology. Shanghai Pujiang ProgramNational Science Foundation (U.S.) (CHE-1019990)National Institute of Environmental Health Sciences (ES002109)Singapore. National Research Foundation (Singapore-MIT Alliance for Research and Technology

    Evaluating the impact of decentralising tuberculosis microscopy services to rural township hospitals in gansu province, china

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    <p>Abstract</p> <p>Background</p> <p>In 2004, the Ministry of Health issued the policy of decentralising microscopy services (MCs) to one third of all township hospitals in China. The study was conducted in Gansu Province, a poor western one in China. Ganzhou was one county in Gansu Province. Ganzhou County was identified as a unique case of further decentralisation of tuberculosis (TB) treatment services in township hospitals. The study evaluated the impact of the MC policy on providers and patients in Gansu Province. The second objective was to assess the unique case of Ganzhou County compared with other counties in the province.</p> <p>Methods</p> <p>Both quantitative and qualitative methods were used. All 523 MCs in the province completed an institutional survey regarding their performance. Four counties were selected for in-depth investigation, where 169 TB suspects were randomly selected from the MC and county TB dispensary registers for questionnaire surveys. Informant interviews were conducted with 38 health staff at the township and county levels in the four counties.</p> <p>Results</p> <p>Gansu established MCs in 39% of its township hospitals. From January 2006 to June 2007, 8% of MCs identified more than 10 TB sputum smear positive patients while 54% did not find any. MCs identified 1546 TB sputum smear positive patients, accounting for 9% of the total in the province. The throughputs of MCs in Ganzhou County were eight times of those in other counties. Interviews identified several barriers to implement the MC policy, such as inadequate health financing, low laboratory capacity, lack of human resources, poor treatment and management capacities, and lack of supervisions from county TB dispensaries.</p> <p>Conclusion</p> <p>Microscopy centre throughputs were generally low in Gansu Province, and the contribution of MCs to TB case detection was insignificant taking account the number of MCs established. As a unique case of full decentralisation of TB service, Ganzhou County presented better results. However, standards and quality of TB care needed to be improved. The MC policy needs to be reviewed in light of evidence from this study.</p
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