JRAD データベースを用いたStanford A型急性大動脈解離の解析

京都大学新制・論文博士博士(医学)乙第13494号論医博第2259号新制||医||1060(附属図書館)(主査)教授 石見 拓, 教授 大鶴 繁, 教授 近藤 尚己学位規則第4条第2項該当Doctor of Medical ScienceKyoto UniversityDFA

The Direct/Indirect Association of ADHD/ODD Symptoms with Self-esteem, Self-perception, and Depression in Early Adolescents

The present study aimed to reveal the influences of attention-deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) symptoms on self-esteem and self-perception during early adolescence and to clarify the spillover effect of self-esteem on depressive symptoms. ADHD symptoms in 564 early adolescents were evaluated via teacher-rating scales. Self-esteem and depressive symptoms were assessed via self-reported scales. We analyzed the relationships among these symptoms using structural equation modeling. Severe inattentive symptoms decreased self-esteem and hyperactive–impulsive symptoms affected self-perception for non-academic domains. Although these ADHD symptoms did not directly affect depressive symptoms, low self-esteem led to severe depression. ODD symptoms had a direct impact on depression without the mediating effects of self-esteem. These results indicated that inattentive symptoms had a negative impact on self-esteem and an indirect negative effect on depressive symptoms in adolescents, even if ADHD symptoms were subthreshold. Severe ODD symptoms can be directly associated with depressive symptoms during early adolescence

“Principles” is the beginning of “philosophy” : A viewpoint from Descartes and toward the future of “physical education philosophy”

　This article attempts to clarify the conceptual difference between“ principles” and“philosophy” from the viewpoint of Descartes and history of the discipline of the“Principles of Physical Education.” The conclusion of this paper will lead us to reconsider the mission of the discipline of “Physical Education Philosophy,” according to its fundamental academic character.　In the field of“ Principles of Physical Education” in Japan, research has continued since the beginning of the twentieth century from the viewpoint of the philosophical method, whereas, in other countries, “Principles of Physical Education” consistently offers some practical knowledge, which is not necessarily philosophical. For a long time, most Japanese researchers have thought of the concepts of “principles” and “philosophy” as the same. However, using Descartes’ Principles of Philosophy, this paper will show that the concepts of “principles” and “philosophy” are totally different. It will become necessary to articulate a clear difference between these things, and to offer some basic academic character to the discipline of “Physical Education Philosophy,” which changed its name from “Principles of Physical Education” in 2005.　According to Descartes, principles are what we would see as the beginning point of philosophy. Philosophy has its root in principles and principles is a part of philosophy, but not the same as philosophy. Philosophy, for Descartes, also has utility for our everyday affairs. He argued that wisdom should be produced from philosophy as practical knowledge. He also presented examples of this in his own writings, such as Dioptric, Meteorology, and Geometry. If we follow Descartes’ view, the discipline of “Physical Education Philosophy” should change its academic character, because so far it has retained the academic character of the previous“Principles of Education.” Researchers of “Physical Education Philosophy” should produce their own output, not only offering some fundamental knowledge for those who engage in physical education and sport, but also offering wisdom as a practical knowledge to practitioners in order to direct their basic thinking.　This will lead to a more enlightened discussion. Spiritual Exercises, proposed by Pierre Hadot, presents a type of essence of wisdom as practical knowledge, which will lead us to reconsider the nature of wisdom in the context of physical education and sport

Chiral Soliton Lattice Formation in Monoaxial Helimagnet Yb(Ni1−x_{1-x}Cux_x)3_3Al9_9

Helical magnetic structures and its responses to external magnetic fields in Yb(Ni$_x$Cu$_{1-x}$)$_3$Al$_9$, with a chiral crystal structure of the space group $R32$, have been investigated by resonant X-ray diffraction. It is shown that the crystal chirality is reflected to the helicity of the magnetic structure by a one to one relationship, indicating that there exists an antisymmetric exchange interaction mediated via the conduction electrons. When a magnetic field is applied perpendicular to the helical axis ($c$ axis), the second harmonic peak of $(0, 0, 2q)$ develops with increasing the field. The third harmonic peak of $(0, 0, 3q)$ has also been observed for the $x$=0.06 sample. This result provides a strong evidence for the formation of a chiral magnetic soliton lattice state, a periodic array of the chiral twist of spins, which has been suggested by the characteristic magnetization curve. The helical ordering of magnetic octupole moments, accompanying with the magnetic dipole order, has also been detected.Comment: 13 pages, 18 figures, accepted for publication in J. Phys. Soc. Jp

Anaplastic Transformation of Follicular Thyroid Carcinoma in Pulmonary Metastasis With Gradually Progressive Intra-tumoral Cavitation: A Case Report

Anaplastic transformation of differentiated thyroid cancer is rare but clinically important because of the dismal prognosis after anaplastic transformation. Therefore, cases and findings of anaplastic transformation must be accumulated, which could ultimately lead to an earlier diagnosis and an improved prognosis. Here, we present a case of anaplastic transformation of follicular thyroid carcinoma (FTC) in a pulmonary metastatic lesion associated with gradually progressive tumor cavitation. The patient with FTC was diagnosed with multiple lung metastases three years after surgery for the primary tumor and metastatic neck lymph nodes. Annual treatment with radioactive iodine resulted in disease stability for 10 years. However, one lung metastasis in the left lower lobe gradually enlarged and was associated with intra-tumoral cavitation. The growing lung nodule was resected and pathologically diagnosed as an anaplastic transformation of FTC. Fourteen months after diagnosis, the patient died of pneumothorax caused by pleural dissemination despite multiple treatment interventions. This case highlights pulmonary metastasis with progressive cavitary lesions as a potential early sign of the anaplastic transformation of differentiated thyroid cancer

中国海南省農村部コミュニティにおける経済発展とC反応性タンパク質濃度に関する研究

学位の種別: 課程博士審査委員会委員 : (主査)東京大学教授 水口 雅, 東京大学教授 神馬 征峰, 東京大学教授 矢冨 裕, 東京大学准教授 近藤 尚己, 東京大学准教授 西浦 博University of Tokyo(東京大学