High-precision epsilon expansions of single-mass-scale four-loop vacuum bubbles

In this article we present a high-precision evaluation of the expansions in \e=(4-d)/2 of (up to) four-loop scalar vacuum master integrals, using the method of difference equations developed by S. Laporta. We cover the complete set of `QED-type' master integrals, i.e. those with a single mass scale only (i.e. $m_i\in\{0,m\}$) and an even number of massive lines at each vertex. Furthermore, we collect all that is known analytically about four-loop `QED-type' masters, as well as about {\em all} single-mass-scale vacuum integrals at one-, two- and three-loop order.Comment: 25 pages, uses axodraw.st

Hamiltonian Cosmological Perturbation Theory

The Hamiltonian approach to cosmological perturbations in general relativity in finite space-time is developed, where a cosmological scale factor is identified with spatial averaging the metric determinant logarithm. This identification preserves the number of variables and leads to a cosmological perturbation theory with the scalar potential perturbations in contrast to the kinetic perturbations in the Lifshitz version which are responsible for the ``primordial power spectrum'' of CMB in the inflationary model. The Hamiltonian approach enables to explain this ``spectrum'' in terms of scale-invariant variables and to consider other topical problem of modern cosmology in the context of quantum cosmological creation of both universes and particles from the stable Bogoliubov vacuum.Comment: 10 pages, text was changed according to the version accepted for publication in Physics Letters

Reduction and evaluation of two-loop graphs with arbitrary masses

We describe a general analytic-numerical reduction scheme for evaluating any 2-loop diagrams with general kinematics and general renormalizable interactions, whereby ten special functions form a complete set after tensor reduction. We discuss the symmetrical analytic structure of these special functions in their integral representation, which allows for optimized numerical integration. The process Z -> bb is used for illustration, for which we evaluate all the 3-point, non-factorizable g^2*alpha_s mixed electroweak-QCD graphs, which depend on the top quark mass. The isolation of infrared singularities is detailed, and numerical results are given for all two-loop three-point graphs involved in this process

Observers in an accelerated universe

If the current acceleration of our Universe is due to a cosmological constant, then a Coleman-De Luccia bubble will nucleate in our Universe. In this work, we consider that our observations could be likely in this framework, consisting in two infinite spaces, if a foliation by constant mean curvature hypersurfaces is taken to count the events in the spacetime. Thus, we obtain and study a particular foliation, which covers the existence of most observers in our part of spacetime.Comment: revised version, accepted in EPJ

Stabilization of internal spaces in multidimensional cosmology

Effective 4-dimensional theories are investigated which were obtained under dimensional reduction of multidimensional cosmological models with a minimal coupled scalar field as matter source. Conditions for the internal space stabilization are considered and the possibility for inflation in the external space is discussed. The electroweak as well as the Planck fundamental scale approaches are investigated and compared with each other. It is shown that there exists a rescaling for the effective cosmological constant as well as for gravitational exciton masses in the different approaches.Comment: 12 pages, LaTeX2e, to appear in Phys.Rev.D, note adde

Variations on the Seventh Route to Relativity

As motivated in the full abstract, this paper further investigates Barbour, Foster and O Murchadha (BFO)'s 3-space formulation of GR. This is based on best-matched lapse-eliminated actions and gives rise to several theories including GR and a conformal gravity theory. We study the simplicity postulates assumed in BFO's work and how to weaken them, so as to permit the inclusion of the full set of matter fields known to occur in nature. We study the configuration spaces of gravity-matter systems upon which BFO's formulation leans. In further developments the lapse-eliminated actions used by BFO become impractical and require generalization. We circumvent many of these problems by the equivalent use of lapse-uneliminated actions, which furthermore permit us to interpret BFO's formulation within Kuchar's generally covariant hypersurface framework. This viewpoint provides alternative reasons to BFO's as to why the inclusion of bosonic fields in the 3-space approach gives rise to minimally-coupled scalar fields, electromagnetism and Yang--Mills theory. This viewpoint also permits us to quickly exhibit further GR-matter theories admitted by the 3-space formulation. In particular, we show that the spin-1/2 fermions of the theories of Dirac, Maxwell--Dirac and Yang--Mills--Dirac, all coupled to GR, are admitted by the generalized 3-space formulation we present. Thus all the known fundamental matter fields can be accommodated. This corresponds to being able to pick actions for all these theories which have less kinematics than suggested by the generally covariant hypersurface framework. For all these theories, Wheeler's thin sandwich conjecture may be posed, rendering them timeless in Barbour's sense.Comment: Revtex version; Journal-ref adde

The Deformable Universe

The concept of smooth deformations of a Riemannian manifolds, recently evidenced by the solution of the Poincar\'e conjecture, is applied to Einstein's gravitational theory and in particular to the standard FLRW cosmology. We present a brief review of the deformation of Riemannian geometry, showing how such deformations can be derived from the Einstein-Hilbert dynamical principle. We show that such deformations of space-times of general relativity produce observable effects that can be measured by four-dimensional observers. In the case of the FLRW cosmology, one such observable effect is shown to be consistent with the accelerated expansion of the universe.Comment: 20 pages, LaTeX, 3 figure

Gravitational excitons from extra dimensions

Inhomogeneous multidimensional cosmological models with a higher dimensional space-time manifold are investigated under dimensional reduction. In the Einstein conformal frame, small excitations of the scale factors of the internal spaces near minima of an effective potential have a form of massive scalar fields in the external space-time. Parameters of models which ensure minima of the effective potentials are obtained for particular cases and masses of gravitational excitons are estimated.Comment: Revised version --- 12 references added, Introduction enlarged, 20 pages, LaTeX, to appear in Phys.Rev.D56 (15.11.97

The Hamiltonian formulation of General Relativity: myths and reality

A conventional wisdom often perpetuated in the literature states that: (i) a 3+1 decomposition of space-time into space and time is synonymous with the canonical treatment and this decomposition is essential for any Hamiltonian formulation of General Relativity (GR); (ii) the canonical treatment unavoidably breaks the symmetry between space and time in GR and the resulting algebra of constraints is not the algebra of four-dimensional diffeomorphism; (iii) according to some authors this algebra allows one to derive only spatial diffeomorphism or, according to others, a specific field-dependent and non-covariant four-dimensional diffeomorphism; (iv) the analyses of Dirac [Proc. Roy. Soc. A 246 (1958) 333] and of ADM [Arnowitt, Deser and Misner, in "Gravitation: An Introduction to Current Research" (1962) 227] of the canonical structure of GR are equivalent. We provide some general reasons why these statements should be questioned. Points (i-iii) have been shown to be incorrect in [Kiriushcheva et al., Phys. Lett. A 372 (2008) 5101] and now we thoroughly re-examine all steps of the Dirac Hamiltonian formulation of GR. We show that points (i-iii) above cannot be attributed to the Dirac Hamiltonian formulation of GR. We also demonstrate that ADM and Dirac formulations are related by a transformation of phase-space variables from the metric $g_{\mu\nu}$ to lapse and shift functions and the three-metric $g_{km}$, which is not canonical. This proves that point (iv) is incorrect. Points (i-iii) are mere consequences of using a non-canonical change of variables and are not an intrinsic property of either the Hamilton-Dirac approach to constrained systems or Einstein's theory itself.Comment: References are added and updated, Introduction is extended, Subsection 3.5 is added, 83 pages; corresponds to the published versio

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART

The precise role of CD4 T cell turnover in maintaining HIV persistence during antiretroviral therapy (ART) has not yet been well characterized. In resting CD4 T cell subpopulations from 24 HIV-infected ART-suppressed and 6 HIV-uninfected individuals, we directly measured cellular turnover by heavy water labeling, HIV reservoir size by integrated HIV-DNA (intDNA) and cell-associated HIV-RNA (caRNA), and HIV reservoir clonality by proviral integration site sequencing. Compared to HIV-negatives, ART-suppressed individuals had similar fractional replacement rates in all subpopulations, but lower absolute proliferation rates of all subpopulations other than effector memory (TEM) cells, and lower plasma IL-7 levels (p = 0.0004). Median CD4 T cell half-lives decreased with cell differentiation from naïve to TEM cells (3 years to 3 months, p<0.001). TEM had the fastest replacement rates, were most highly enriched for intDNA and caRNA, and contained the most clonal proviral expansion. Clonal proviruses detected in less mature subpopulations were more expanded in TEM, suggesting that they were maintained through cell differentiation. Earlier ART initiation was associated with lower levels of intDNA, caRNA and fractional replacement rates. In conclusion, circulating integrated HIV proviruses appear to be maintained both by slow turnover of immature CD4 subpopulations, and by clonal expansion as well as cell differentiation into effector cells with faster replacement rates